Ltbp1 (NM_206958) Mouse Untagged Clone
CAT#: MC224375
Ltbp1 (untagged) - Mouse latent transforming growth factor beta binding protein 1 (Ltbp1), transcript variant 2, (10ug)
CNY 17,860.00
Product images
![](https://cdn.origene.com/img/defaults-img.jpg)
Specifications
Product Data | |
Type | Mouse Untagged Clone |
Tag | Tag Free |
Synonyms | 9430031G15Rik; 9830146M04; b2b1000Clo; Ltbp-1; Ltbp1L; TGF-beta1-BP-1; Tgfb |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>MC224375 representing NM_206958
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGATACTAAGCTGATGTGTTTGTTGTTCTTTCTCTGTCTGCCTCTACTCCTAGTGAGTAACCACACTG GTCGCATCAAGGTGGTCTTTACTCCGAGCATCTGTAAAGTGACCTGCACCAAGGGCAACTGTCAGAACAG CTGCCAGAAGGGGAATACCACCACTCTCATTAGTGAGAACGGCCATGCAGCCGACACCCTGACAGCCACG AACTTCCGAGTGGTTATTTGCCATCTTCCGTGTATGAATGGTGGCCAGTGCAGTTCAAGGGACAAATGTC AGTGCCCTCCAAATTTCACAGGAAAGCTTTGCCAGATCCCTGTCCTTGGTGCCAGTATGCCCAAACTCTA CCAGCACGCCCAGCAGCAGGGCAAGGCATTGGGGAGTCACGTCATCCATTCCACACATACCTTGCCTCTA ACCATGACTAGCCAGCAAGGGGTCAAAGTGAAATTCCCCCCCAACATAGTCAATATCCATGTGAAACATC CTCCCGAGGCTTCTGTCCAGATACACCAGGTTTCCAGGATTGACAGCCCAGGAGGCCAGAAGGTGAAGGA AGCCCAACCAGGCCAGTCCCAAGTCTCTTACCAAGGACTTCCGGTCCAGAAGACCCAGACAGTCCATTCT ACGTACTCCCACCAGCAGCTTATTCCCCATGTGTATCCCGTGGCTGCTAAGACACAACTTGGCCGATGCT TCCAGGAAACCATTGGATCACAGTGTGGCAAAGCGCTCCCTGGCCTTTCCAAGCAAGAGGACTGCTGTGG GACAGTGGGGACGTCCTGGGGCTTTAACAAATGCCAGAAGTGCCCCAAGAAACAATCCTATCATGGATAT ACTCAAATGATGGAATGCCTACAAGGATATAAACGGGTTAACAACACCTTTTGTCAAGATATTAATGAAT GTCAGCTACAAGGTGTATGCCCTAATGGTGAGTGTTTGAATACCATGGGCAGCTACAGATGCTCCTGCAA AATGGGATTCGGGCCTGACCCTACCTTTTCAAGTTGTGTTCCGGATCCCCCTGTGATCTCAGAAGAGAAA GGGCCCTGTTACCGCCTTGTCAGTCCTGGAAGGCATTGTATGCACCCTCTCTCTGTTCATCTCACCAAGC AGATCTGCTGTTGTAGTGTGGGCAAGGCCTGGGGCCCACATTGTGAGAAATGTCCCCTCCCAGGCACAGC TGCTTTTAAGGAAATCTGTCCTGGTGGAATGGGTTATACGGTTTCTGGCGTTCATAGACGCAGGCCAATC CATCAGCATATAGGTAAAGAAGCTGTATATGTCAAGCCAAAGAACACTCAACCTGTTGCTAAAAGTACTC ATCCTCCACCTCTCCCAGCCAAGGAAGAGCCTGTGGAGGCCCTGACCTCCTCGTGGGAACACGGGCCGAG AGGGGCGGAGCCCGAAGTGGTAACAGCACCTCCTGAGAAGGAAATACCTTCACTGGATCAAGAGAAAACC AGACTTGAACCTGGGCAACCCCAGCTCTCCCCAGGGGTTTCAACTATTCATCTGCACCCACAGTTTCCAG TAGTGGTTGAAAAGACATCCCCTCCTGTGCCTGTGGAAGTAGCTCCTGAAGCTTCCACATCCAGTGCCAG CCAAGTGATTGCTCCTACGCAAGTAACAGAAATCAACGAATGTACTGTGAACCCGGACATTTGCGGAGCA GGACACTGCATCAACCTGCCGGTGCGGTATACCTGCATATGCTACGAGGGCTACAAGTTCAGTGAACAGC TGAGGAAATGTGTCGACATTGATGAATGTGCTCAGGTCCGGCACCTCTGCTCCCAGGGTCGCTGTGAGAA CACAGAGGGAAGTTTCCTGTGTGTCTGCCCGGCAGGGTTTATGGCCAGTGAGGAGGGTACTAACTGTATA GATGTGGATGAGTGCCTGAGGCCTGATATGTGTAGGGATGGCCGCTGCATCAACACCGCTGGGGCCTTCC GGTGCGAGTACTGTGACAGTGGGTACCGGATGTCACGGAGAGGCTACTGTGAGGATATTGATGAGTGTCT GAAGCCAAGCACTTGTCCCGAGGAACAGTGTGTGAACACCCCGGGCTCTTACCAGTGTGTGCCCTGCACA GAGGGGTTCCGCGGCTGGAATGGACAATGCCTTGATGTGGACGAGTGCCTGCAGCCAAAGGTCTGTACGA ATGGTTCCTGCACCAACCTGGAAGGGTCCTACATGTGTTCCTGCCACAGGGGCTACAGCCCCACACCAGA CCATAGACACTGTCAAGATATTGATGAATGCCAACAAGGGAATCTCTGCATGAATGGGCAGTGCAGAAAT ACCGATGGCTCCTTCCGGTGTACCTGTGGACAGGGCTATCAGCTGTCAGCAGCTAAAGACCAATGTGAAG ATATTGATGAATGCGAGCACCATCACCTCTGCTCTCACGGGCAGTGCAGGAACACAGAGGGCTCCTTCCA GTGTGTGTGCAACCAGGGTTACAGAGCATCTGTACTTGGAGACCACTGTGAGGATATCAATGAATGCTTG GAGGACAGCAGTGTCTGCCAGGGAGGTGACTGCATCAATACTGCGGGGTCCTATGATTGCACATGCCCGG ATGGATTCCAGCTGAACGACAATAAGGGCTGTCAAGACATTAATGAATGTGCACAGCCAGGACTCTGTGG ATCTCATGGGGAGTGTCTAAACACACAAGGCTCCTTCCACTGTGTCTGTGAACAGGGGTTCTCCATCTCT GCCGATGGCCGTACATGCGAAGATATTGATGAGTGTGTTAACAACACTGTGTGTGACAGTCACGGCTTCT GTGACAACACAGCCGGCTCTTTCCGCTGCCTCTGTTATCAGGGCTTTCAAGCCCCACAGGATGGGCAAGG GTGTGTGGATGTGAACGAGTGTGAACTGCTCAGTGGTGTATGTGGGGAAGCCTTCTGTGAAAACGTGGAA GGATCCTTCCTGTGTGTGTGTGCCGATGAGAACCAGGAGTACAGCCCCATGACTGGGCAGTGTCGCTCTC GGGTCACGGAAGATTCAGGTGTGGATCGTCAGCCTAGAGAAGAGAAGAAGGAGTGCTATTATAACCTCAA TGATGCTAGTCTCTGTGATAATGTCCTGGCCCCCAACGTCACCAAACAAGAGTGCTGCTGTACGTCAGGT GCCGGCTGGGGAGACAACTGTGAGATCTTCCCTTGCCCCGTCCAGGGAACTGCTGAGTTCACGGAAATGT GCCCTAGAGGGAAAGGTTTGGTCCCGGCTGGAGAATCCTCTTACGACACTGGTGGCGAGAACTACAAAGA TGCTGATGAATGCTTGCTGTTTGGAGAGGAAATCTGTAAAAATGGTTACTGTTTGAACACTCAACCTGGG TATGAATGCTACTGTAAGCAAGGGACATACTATGATCCTGTCAAATTACAGTGCTTTGATATGGATGAAT GCCAAGACCCTAACAGTTGCATTGACGGCCAGTGTGTGAACACAGAGGGCTCCTACAACTGCTTTTGCAC CCACCCAATGGTCCTGGATGCCTCTGAGAAGAGATGTGTGCAACCAACTGAATCAAATGAACAAATAGAA GAGACCGATGTCTATCAAGATCTGTGCTGGGAGCATCTGAGTGAGGAGTACGTGTGTAGCCGTCCTCTCG TAGGCAAGCAGACGACGTACACAGAATGCTGCTGTTTGTACGGGGAGGCTTGGGGCATGCAGTGTGCTCT GTGCCCCATGAAGGACTCAGATGACTATGCCCAGCTGTGCAATATCCCTGTGACTGGGCGTCGGCGGCCA TATGGACGGGATGCATTGGTGGACTTCAGTGAACAGTATGGCCCAGAAACAGACCCTTACTTCATCCAGG ATCGCTTTCTAAATAGCTTTGAGGAGCTACAGGCTGAGGAGTGTGGCATCCTCAATGGTTGTGAAAACGG CCGCTGTGTGAGAGTCCAGGAAGGATACACTTGCGATTGCTTTGATGGATATCACCTGGATATGGCCAAG ATGACCTGTGTCGATGTAAATGAATGCAGCGAGCTGAATAATCGGATGTCTCTCTGCAAGAACGCCAAGT GCATTAACACAGAAGGCTCCTACAAATGCTTGTGTCTGCCAGGCTACATACCATCCGACAAGCCCAACTA CTGTACACCCCTGAACAGCGCTTTGAATTTAGACAAAGAAAGTGACCTGGAGTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
Restriction Sites | SgfI-MluI |
ACCN | NM_206958 |
Insert Size | 4185 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_206958.2, NP_996841.1 |
RefSeq Size | 6771 bp |
RefSeq ORF | 4185 bp |
Locus ID | 268977 |
UniProt ID | Q8CG19 |
Gene Summary | Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space. Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta. Outcompeted by LRRC32/GARP for binding to LAP regulatory chain of TGF-beta.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region, and has an alternate 5' coding segment, compared to variant 1. The encoded isoform (LTBP-1S) has a shorter and distinct N-terminus when compared to isoform LTBP-1L. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MG211964 | Ltbp1 (tGFP-tagged) - Mouse latent transforming growth factor beta binding protein 1 (Ltbp1), transcript variant 2 |
CNY 13,490.00 |
|
MR211964 | Ltbp1 (Myc-DDK-tagged) - Mouse latent transforming growth factor beta binding protein 1 (Ltbp1), transcript variant 2 |
CNY 9,536.00 |
|
MR211964L3 | Lenti ORF clone of Ltbp1 (Myc-DDK-tagged) - Mouse latent transforming growth factor beta binding protein 1 (Ltbp1), transcript variant 2 |
CNY 14,160.00 |
|
MR211964L4 | Lenti ORF clone of Ltbp1 (mGFP-tagged) - Mouse latent transforming growth factor beta binding protein 1 (Ltbp1), transcript variant 2 |
CNY 14,160.00 |