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Tnik (NM_001163009) Mouse Untagged Clone
CAT＃: MC224348
Tnik (untagged) - Mouse TRAF2 and NCK interacting kinase (Tnik), transcript variant 4, (10ug)
CNY 17,480.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 1500031A17Rik; 4831440I19Rik; AI451411; C530008O15Rik; C630040K21Rik |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC224348 representing NM_001163009
Red=Cloning site Blue=ORF TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCGAGCGACTCCCCAGCTCGCAGCCTGGATGAAATCGATCTCTCCGCCCTGAGGGACCCTGCAGGGA TCTTTGAGTTGGTGGAACTTGTCGGAAATGGCACGTATGGTCAAGTTTATAAGGGTCGTCATGTCAAAAC GGGCCAGCTTGCTGCCATTAAGGTTATGGATGTCACAGGGGATGAAGAGGAAGAAATCAAACAAGAAATT AACATGTTGAAGAAATATTCTCATCACAGGAACATTGCTACATACTACGGTGCTTTTATCAAAAAGAACC CTCCTGGCATGGATGACCAACTCTGGTTGGTTATGGAGTTCTGTGGTGCTGGCTCTGTCACTGACCTGAT CAAGAACACGAAAGGCAACACATTGAAAGAGGAGTGGATTGCATACATCTGCAGGGAGATCTTACGGGGC CTGAGTCACCTGCACCAGCACAAAGTGATTCATCGAGATATCAAAGGGCAGAACGTCTTGTTGACTGAAA ATGCAGAGGTTAAGCTAGTGGATTTTGGAGTGAGTGCCCAGCTTGACCGAACTGTGGGCAGGAGGAACAC GTTCATCGGGACTCCCTACTGGATGGCACCAGAAGTCATTGCCTGTGATGAGAACCCGGATGCCACATAT GATTTCAAGAGTGACTTGTGGTCTTTGGGAATCACCGCCATTGAGATGGCAGAAGGTGCCCCCCCCCTCT GTGACATGCATCCCATGAGAGCCCTCTTCCTCATCCCACGGAACCCTGCACCTCGGCTCAAGTCTAAGAA GTGGTCAAAAAAATTCCAGTCATTTATCGAGAGCTGCTTGGTAAAGAATCACAGCCAGCGGCCAGCCACG GAGCAGTTGATGAAGCACCCATTCATACGAGACCAACCTAATGAGAGGCAGGTCCGCATCCAGCTGAAGG ACCACATTGATCGAACAAAGAAGAAGCGAGGAGAAAAAGATGAGACTGAGTATGAATACAGCGGAAGTGA GGAAGAAGAGGAAGAGAATGACTCTGGGGAACCCAGCTCCATTCTGAACCTACCAGGGGAGTCAACACTG CGAAGGGACTTCCTGAGACTGCAGCTGGCCAACAAGGAGCGCTCAGAGGCCCTGCGGCGCCAACAGCTGG AGCAGCAGCAGCGGGAGAATGAAGAACACAAGCGGCAGCTACTGGCTGAGCGCCAGAAGCGCATCGAAGA GCAGAAGGAGCAAAGGCGGAGGCTGGAGGAGCAACAAAGGCGAGAAAAAGAGCTTCGGAAACAGCAGGAG CGGGAACAGCGCCGGCACTACGAAGAACAGATGCGTCGGGAGGAGGAGAGGAGGCGTGCCGAACATGAGC AGGAATACATCAGGCGGCAGCTAGAAGAAGAGCAAAGGCAGTTAGAGATCTTACAGCAGCAGCTACTGCA TGAGCAAGCTCTACTTCTGGAATATAAGCGCAAACAATTGGAAGAACAGAGACAAGCAGAAAGACTGCAG AGGCAGCTAAAGCAAGAGCGGGACTATCTGGTTTCCCTCCAGCATCAGCGGCAGGAGCAGAGGCCCCTGG AGAAGAAGCCACTGTACCATTACAAGGAGGGCATGAGTCCTAGTGAGAAGCCGGCCTGGGCCAAGGAGGT AGAAGAACGCTCAAGACTCAACCGACAGAGTTCACCTGCCATGCCTCACAAGGTTGCCAACAGGATCTCG GACCCCAACCTGCCCCCAAGATCAGAGTCCTTCAGCATTAGTGGGGTTCAGCCTGCAAGGACACCCCCAA TGCTCAGACCTGTTGACCCCCAGATCCCGCAGCTGGTAGCTGTCAAATCCCAGGGACCTGCCTTGACGGC CTCCCAGTCAGTACATGAGCAACCCACAAAGGGCCTGTCTGGGTTCCAGGAGGCTCTGAATGTGACCTCT CACCGGGTCGAGATGCCACGCCAGAACTCGGATCCCACCTCAGAAAACCCTCCTCTCCCCACGAGAATTG AGAAGTTTGACAGAAGCTCTTGGTTACGACAGGAAGAAGACATTCCACCAAAGGTGCCTCAAAGAACAAC TTCTATATCCCCAGCACTAGCCAGAAAGAATTCCCCTGGCAATGGCAGTGCTCTGGGCCCCAGACTTGGA TCTCAGCCCATCAGAGCAAGCAACCCTGATCTGCGCAGGACAGAGCCAGTCCTGGAGAGTTCCCTGCAGC GGACAAGCAGTGGCAGTTCCTCCAGCTCCAGCACTCCCAGCTCCCAGCCCAGCTCCCAAGGAGGCTCTCA ACCTGGCTCCCAAGCAGGATCTAGTGAGCGGTCCAGAGTGCGGGCCAACAGTAAGTCCGAAGGATCACCC GTGCTCCCCCATGAGCCTTCCAAGGTGAAACCAGAAGAATCCAGAGACATCACACGGCCCAGTCGGCCAG CTGATCTGACGGCATTAGCCAAAGAATTACGAGAACTCCGCATTGAAGAAACAAACCGCCCCCTGAAGAA AGTGACTGATTACTCTTCCTCCAGCGAGGAGTCGGAGAGCAGTGAGGAAGAAGAGGAAGATGGAGAGAGT GAGACACATGACGGGACGGTGGCTGTCAGTGACATACCCAGACTAATACCCACCGGAGCTCCAGGGAACA ATGAGCAGTACAACATGGGGATGGTCGGGACACATGGGCTGGAAACTTCGCATGCGGACACCTTTGGCGG CAGCATTTCAAGAGAAGGAACCTTGATGATCAGAGAGACGGCTGAAGAGAAGAAGCGATCTGGCCACAGT GACAGTAATGGATTCGCCGGTCACATCAATCTCCCAGACCTTGTACAGCAGAGCCATTCGCCAGCTGGAA CTCCCACTGAGGGGCTGGGCCGCGTCTCCACTCATTCCCAGGAGATGGACTCTGGGGCTGAATATGGTAT AGGGAGCAGCACCAAAGCCTCTTTCACCCCCTTCGTGGACCCTCGAGTGTACCAGACATCGCCCACTGAT GAAGATGAAGAGGATGATGAGTCTTCAGCTGCTGCCCTGTTTACTAGCGAACTTCTTAGGCAAGAACAGG CCAAACTCAATGAAGCGAGGAAGATTTCAGTGGTAAATGTGAACCCAACAAACATTCGCCCTCATAGTGA CACACCGGAAATCAGAAAATACAAGAAACGCTTCAATTCAGAAATACTTTGTGCAGCTCTATGGGGTGTG AACCTTCTGGTGGGGACTGAAAATGGCCTGATGCTTTTGGACAGAAGTGGCCAAGGCAAAGTCTACAACC TAATCAACCGGAGGCGGTTTCAGCAGATGGATGTGCTAGAAGGACTAAATGTTCTTGTCACGATATCAGG AAAGAAGAACAAGCTCCGTGTGTACTATCTCTCATGGTTAAGAAACAGAATCCTGCACAATGACCCAGAA GTGGAAAAGAAGCAGGGCTGGATCACTGTCGGTGACTTGGAAGGCTGCATCCATTACAAAGTCGTTAAAT ATGAAAGAATCAAGTTCCTGGTGATTGCCTTAAAGAATGCAGTAGAGATATATGCGTGGGCCCCTAAACC TTACCATAAGTTCATGGCATTTAAGTCTTTTGCAGATCTTCAGCATAAGCCTCTGCTCGTTGACCTCACA GTAGAAGAAGGTCAAAGGTTAAAGGTCATATTTGGCTCACACACTGGTTTCCATGTAATTGATGTTGATT CTGGAAACTCCTACGATATCTATATACCATCCCATATTCAGGGCAATATCACTCCTCATGCTATCGTCAT CTTGCCTAAAACAGATGGAATGGAGATGCTTGTCTGCTATGAGGATGAAGGGGTGTACGTGAACACCTAC GGCCGGATCACTAAGGATGTGGTGCTCCAATGGGGAGAAATGCCCACATCTGTGGCCTACATTCATTCCA ATCAGATAATGGGCTGGGGCGAGAAAGCTATTGAGATCCGGTCAGTGGAAACAGGACATTTGGATGGAGT GTTTATGCATAAACGAGCTCAAAGGTTAAAGTTTCTATGTGAAAGAAATGATAAGGTAAATCCGTTTCAA CTTTGCTTTAGTGTTTGCATTTTAAGAGACCACCAGGTACCTGTGAAACCTTCATTTTCCTTTATACTGA CTCAAGTCACATCTGTGTTCAATGATCAATGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001163009 |
| Insert Size | 4092 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001163009.1, NP_001156481.1 |
| RefSeq Size | 4625 bp |
| RefSeq ORF | 4092 bp |
| Locus ID | 665113 |
| Gene Summary | Serine/threonine kinase that acts as an essential activator of the Wnt signaling pathway. Recruited to promoters of Wnt target genes and required to activate their expression. May act by phosphorylating TCF4/TCF7L2. Appears to act upstream of the JUN N-terminal pathway. May play a role in the response to environmental stress. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it may play a role in cytoskeletal rearrangements and regulate cell spreading (By similarity).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (4) lacks an internal, in-frame coding exon, and differs at the 3' end compared to variant 1, resulting in a longer isoform (4) with a distinct C-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG222147 | Tnik (tGFP-tagged) - Mouse TRAF2 and NCK interacting kinase (Tnik) transcript variant 4, (10ug) |
CNY 11,880.00 |
|
| MR222147 | Tnik (Myc-DDK-tagged) - Mouse TRAF2 and NCK interacting kinase (Tnik), transcript variant 4 |
CNY 9,336.00 |
|
| MR222147L3 | Lenti ORF clone of Tnik (Myc-DDK-tagged) - Mouse TRAF2 and NCK interacting kinase (Tnik), transcript variant 4 |
CNY 12,730.00 |
|
| MR222147L4 | Lenti ORF clone of Tnik (mGFP-tagged) - Mouse TRAF2 and NCK interacting kinase (Tnik), transcript variant 4 |
CNY 12,730.00 |
