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Tnik (NM_001163008) Mouse Untagged Clone
CAT＃: MC224255
Tnik (untagged) - Mouse TRAF2 and NCK interacting kinase (Tnik), transcript variant 3, (10ug)
CNY 17,010.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 1500031A17Rik; 4831440I19Rik; AI451411; C530008O15Rik; C630040K21Rik |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC224255 representing NM_001163008
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCGAGCGACTCCCCAGCTCGCAGCCTGGATGAAATCGATCTCTCCGCCCTGAGGGACCCTGCAGGGA TCTTTGAGTTGGTGGAACTTGTCGGAAATGGCACGTATGGTCAAGTTTATAAGGGTCGTCATGTCAAAAC GGGCCAGCTTGCTGCCATTAAGGTTATGGATGTCACAGGGGATGAAGAGGAAGAAATCAAACAAGAAATT AACATGTTGAAGAAATATTCTCATCACAGGAACATTGCTACATACTACGGTGCTTTTATCAAAAAGAACC CTCCTGGCATGGATGACCAACTCTGGTTGGTTATGGAGTTCTGTGGTGCTGGCTCTGTCACTGACCTGAT CAAGAACACGAAAGGCAACACATTGAAAGAGGAGTGGATTGCATACATCTGCAGGGAGATCTTACGGGGC CTGAGTCACCTGCACCAGCACAAAGTGATTCATCGAGATATCAAAGGGCAGAACGTCTTGTTGACTGAAA ATGCAGAGGTTAAGCTAGTGGATTTTGGAGTGAGTGCCCAGCTTGACCGAACTGTGGGCAGGAGGAACAC GTTCATCGGGACTCCCTACTGGATGGCACCAGAAGTCATTGCCTGTGATGAGAACCCGGATGCCACATAT GATTTCAAGAGTGACTTGTGGTCTTTGGGAATCACCGCCATTGAGATGGCAGAAGGTGCCCCCCCCCTCT GTGACATGCATCCCATGAGAGCCCTCTTCCTCATCCCACGGAACCCTGCACCTCGGCTCAAGTCTAAGAA GTGGTCAAAAAAATTCCAGTCATTTATCGAGAGCTGCTTGGTAAAGAATCACAGCCAGCGGCCAGCCACG GAGCAGTTGATGAAGCACCCATTCATACGAGACCAACCTAATGAGAGGCAGGTCCGCATCCAGCTGAAGG ACCACATTGATCGAACAAAGAAGAAGCGAGGAGAAAAAGATGAGACTGAGTATGAATACAGCGGAAGTGA GGAAGAAGAGGAAGAGAATGACTCTGGGGAACCCAGCTCCATTCTGAACCTACCAGGGGAGTCAACACTG CGAAGGGACTTCCTGAGACTGCAGCTGGCCAACAAGGAGCGCTCAGAGGCCCTGCGGCGCCAACAGCTGG AGCAGCAGCAGCGGGAGAATGAAGAACACAAGCGGCAGCTACTGGCTGAGCGCCAGAAGCGCATCGAAGA GCAGAAGGAGCAAAGGCGGAGGCTGGAGGAGCAACAAAGGCGAGAAAAAGAGCTTCGGAAACAGCAGGAG CGGGAACAGCGCCGGCACTACGAAGAACAGATGCGTCGGGAGGAGGAGAGGAGGCGTGCCGAACATGAGC AGGAATATAAGCGCAAACAATTGGAAGAACAGAGACAAGCAGAAAGACTGCAGAGGCAGCTAAAGCAAGA GCGGGACTATCTGGTTTCCCTCCAGCATCAGCGGCAGGAGCAGAGGCCCCTGGAGAAGAAGCCACTGTAC CATTACAAGGAGGGCATGAGTCCTAGTGAGAAGCCGGCCTGGGCCAAGGAGGTAGAAGAACGCTCAAGAC TCAACCGACAGAGTTCACCTGCCATGCCTCACAAGGTTGCCAACAGGATCTCGGACCCCAACCTGCCCCC AAGATCAGAGTCCTTCAGCATTAGTGGGGTTCAGCCTGCAAGGACACCCCCAATGCTCAGACCTGTTGAC CCCCAGATCCCGCAGCTGGTAGCTGTCAAATCCCAGGGACCTGCCTTGACGGCCTCCCAGTCAGTACATG AGCAACCCACAAAGGGCCTGTCTGGGTTCCAGGAGGCTCTGAATGTGACCTCTCACCGGGTCGAGATGCC ACGCCAGAACTCGGATCCCACCTCAGAAAACCCTCCTCTCCCCACGAGAATTGAGAAGTTTGACAGAAGC TCTTGGTTACGACAGGAAGAAGACATTCCACCAAAGGTGCCTCAAAGAACAACTTCTATATCCCCAGCAC TAGCCAGAAAGAATTCCCCTGGCAATGGCAGTGCTCTGGGCCCCAGACTTGGATCTCAGCCCATCAGAGC AAGCAACCCTGATCTGCGCAGGACAGAGCCAGTCCTGGAGAGTTCCCTGCAGCGGACAAGCAGTGGCAGT TCCTCCAGCTCCAGCACTCCCAGCTCCCAGCCCAGCTCCCAAGGAGGCTCTCAACCTGGCTCCCAAGCAG GATCTAGTGAGCGGTCCAGAGTGCGGGCCAACAGTAAGTCCGAAGGATCACCCGTGCTCCCCCATGAGCC TTCCAAGGTGAAACCAGAAGAATCCAGAGACATCACACGGCCCAGTCGGCCAGCTGATCTGACGGCATTA GCCAAAGAATTACGAGAACTCCGCATTGAAGAAACAAACCGCCCCCTGAAGAAAGTGACTGATTACTCTT CCTCCAGCGAGGAGTCGGAGAGCAGTGAGGAAGAAGAGGAAGATGGAGAGAGTGAGACACATGACGGGAC GGTGGCTGTCAGTGACATACCCAGACTAATACCCACCGGAGCTCCAGGGAACAATGAGCAGTACAACATG GGGATGGTCGGGACACATGGGCTGGAAACTTCGCATGCGGACACCTTTGGCGGCAGCATTTCAAGAGAAG GAACCTTGATGATCAGAGAGACGGCTGAAGAGAAGAAGCGATCTGGCCACAGTGACAGTAATGGATTCGC CGGTCACATCAATCTCCCAGACCTTGTACAGCAGAGCCATTCGCCAGCTGGAACTCCCACTGAGGGGCTG GGCCGCGTCTCCACTCATTCCCAGGAGATGGACTCTGGGGCTGAATATGGTATAGGGAGCAGCACCAAAG CCTCTTTCACCCCCTTCGTGGACCCTCGAGTGTACCAGACATCGCCCACTGATGAAGATGAAGAGGATGA TGAGTCTTCAGCTGCTGCCCTGTTTACTAGCGAACTTCTTAGGCAAGAACAGGCCAAACTCAATGAAGCG AGGAAGATTTCAGTGGTAAATGTGAACCCAACAAACATTCGCCCTCATAGTGACACACCGGAAATCAGAA AATACAAGAAACGCTTCAATTCAGAAATACTTTGTGCAGCTCTATGGGGTGTGAACCTTCTGGTGGGGAC TGAAAATGGCCTGATGCTTTTGGACAGAAGTGGCCAAGGCAAAGTCTACAACCTAATCAACCGGAGGCGG TTTCAGCAGATGGATGTGCTAGAAGGACTAAATGTTCTTGTCACGATATCAGGAAAGAAGAACAAGCTCC GTGTGTACTATCTCTCATGGTTAAGAAACAGAATCCTGCACAATGACCCAGAAGTGGAAAAGAAGCAGGG CTGGATCACTGTCGGTGACTTGGAAGGCTGCATCCATTACAAAGTCGTTAAATATGAAAGAATCAAGTTC CTGGTGATTGCCTTAAAGAATGCAGTAGAGATATATGCGTGGGCCCCTAAACCTTACCATAAGTTCATGG CATTTAAGTCTTTTGCAGATCTTCAGCATAAGCCTCTGCTCGTTGACCTCACAGTAGAAGAAGGTCAAAG GTTAAAGGTCATATTTGGCTCACACACTGGTTTCCATGTAATTGATGTTGATTCTGGAAACTCCTACGAT ATCTATATACCATCCCATATTCAGGGCAATATCACTCCTCATGCTATCGTCATCTTGCCTAAAACAGATG GAATGGAGATGCTTGTCTGCTATGAGGATGAAGGGGTGTACGTGAACACCTACGGCCGGATCACTAAGGA TGTGGTGCTCCAATGGGGAGAAATGCCCACATCTGTGGCCTACATTCATTCCAATCAGATAATGGGCTGG GGCGAGAAAGCTATTGAGATCCGGTCAGTGGAAACAGGACATTTGGATGGAGTGTTTATGCATAAACGAG CTCAAAGGTTAAAGTTTCTATGTGAAAGAAATGATAAGGTATTTTTTGCATCCGTGCGATCTGGAGGAAG TAGCCAAGTGTTTTTCATGACCCTCAACAGAAATTCCATGATGAACTGGTAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001163008 |
| Insert Size | 3972 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001163008.1, NP_001156480.1 |
| RefSeq Size | 7035 bp |
| RefSeq ORF | 3972 bp |
| Locus ID | 665113 |
| UniProt ID | P83510 |
| Gene Summary | Serine/threonine kinase that acts as an essential activator of the Wnt signaling pathway. Recruited to promoters of Wnt target genes and required to activate their expression. May act by phosphorylating TCF4/TCF7L2. Appears to act upstream of the JUN N-terminal pathway. May play a role in the response to environmental stress. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it may play a role in cytoskeletal rearrangements and regulate cell spreading (By similarity).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (3) lacks two internal, in-frame coding exons compared to variant 1, resulting in a shorter isoform (3) missing two protein segments compared to isoform 1. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG221909 | Tnik (tGFP-tagged) - Mouse TRAF2 and NCK interacting kinase (Tnik) transcript variant 3, (10ug) |
CNY 14,540.00 |
|
| MR221909 | Tnik (Myc-DDK-tagged) - Mouse TRAF2 and NCK interacting kinase (Tnik), transcript variant 3 |
CNY 13,210.00 |
|
| MR221909L3 | Lenti ORF clone of Tnik (Myc-DDK-tagged) - Mouse TRAF2 and NCK interacting kinase (Tnik), transcript variant 3 |
CNY 15,110.00 |
|
| MR221909L4 | Lenti ORF clone of Tnik (mGFP-tagged) - Mouse TRAF2 and NCK interacting kinase (Tnik), transcript variant 3 |
CNY 15,110.00 |
