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Abcc4 (NM_001163676) Mouse Untagged Clone
CAT＃: MC224076
Abcc4 (untagged) - Mouse ATP-binding cassette, sub-family C (CFTR/MRP), member 4 (Abcc4), transcript variant 3, (10ug)
CNY 16,060.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | ABCC4-N1; D630049P08Rik; MOATB; MRP4 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC224076 representing NM_001163676
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCTGCCGGTGCACACCGAGGTGAAACCCAACCCGCTGCAGGACGCCAACCTCTGCTCGCGCGTGTTCT TCTGGTGGCTCAACCCGCTGTTTAAAACTGGTCATAAGCGGAGACTGGAAGAAGATGACATGTTCTCAGT GCTTCCAGAAGATCGCTCAAAGCACCTCGGAGAGGAGCTTCAACGGTACTGGGATAAAGAACTTCTGCGA GCCAAGAAGGACTCGAGGAAGCCCTCCTTAACAAAGGCAATCATAAAGTGTTACTGGAAGTCTTACCTGA TTTTGGGAATTTTTACGTTAATTGAGGCACTCCGGTTAAGTAACTCGGCCATGGGGAAGACAACCACAGG CCAGATAGTTAACCTGCTGTCCAACGACGTGAACAAATTCGACCAAGTGACAATCTTCTTGCACTTTCTG TGGGCAGGGCCGCTGCAGGCCATCGCGGTAACCGTCCTCCTCTGGGTGGAGATAGGAATCTCCTGCCTGG CGGGCTTGGCCGTTCTGGTTATTCTTCTGCCTCTGCAAAGCTGCATCGGGAAGCTGTTCTCGTCACTGCG GAGTAAAACTGCGGCTTTCACGGATGCCAGGATCCGGACCATGAATGAAGTCATAACAGGCATGAGGATA ATAAAGATGTATGCGTGGGAGAAATCGTTTGCTGACCTCATTGCCAATCTGAGAAAGAAGGAGATTTCCA AGATTCTGGGCAGCTCCTACCTCAGAGGGATGAACATGGCGTCGTTTTTCATCGCAAACAAAGTCATCCT GTTCGTGACCTTCACTAGCTACGTGCTGCTTGGCAATGAGATTACAGCTAGCCACGTGTTTGTGGCCATG ACTCTGTACGGTGCCGTTCGGTTGACAGTCACCCTCTTCTTCCCGTCAGCCATTGAGAGAGGGTCAGAGG CCATCGTCAGCATTCGGAGGATCAAGAACTTTCTGTTACTCGATGAACTACCACAGCGCAAAGCCCATGT ACCATCTGATGGCAAAGCCATTGTCCACGTGCAAGATTTCACCGCTTTCTGGGACAAGGCACTAGACAGT CCAACCCTGCAAGGTCTTTCCTTTATTGCCAGGCCTGGTGAGTTGTTAGCCGTGGTTGGCCCAGTTGGAG CAGGCAAGTCGTCGCTGTTGAGCGCAGTGCTGGGTGAGCTGCCTCCTGCCAGCGGGCTGGTCAGCGTGCA CGGGAGGATCGCCTACGTTTCTCAGCAGCCCTGGGTGTTCTCGGGCACCGTGAGGAGCAATATTTTATTT GGGAAGAAATATGAGAAGGAGCGATATGAGAAAGTGATCAAGGCCTGTGCTCTGAAGAAGGACCTGCAGC TTCTGGAGGACGGGGATCTGACGGTTATAGGAGACCGGGGAGCCACGCTGAGTGGAGGCCAGAAAGCTCG GGTGAACCTGGCACGGGCCGTCTACCAGGACGCCGACATCTACCTCCTTGATGATCCGCTCAGCGCTGTC GATGCAGAAGTGGGCAAGCACCTGTTCCAACTGTGTATCTGTCAGGCGTTGCACGAGAAGATCACCATTT TAGTGACTCACCAGTTACAGTACCTCAAAGCTGCAAGCCACATCCTCATACTCAAAGATGGTGAGATGGT GCAGAAGGGGACTTACACGGAGTTTCTGAAATCTGGTGTAGATTTTGGCTCCCTGTTAAAGAAAGAAAAC GAGGAAGCAGAGCCCTCCACAGCCCCAGGAACCCCGACACTCAGGAAACGAACCTTCTCCGAGGCCTCAA TTTGGTCTCAGCAGTCATCCAGACCCTCGTTGAAAGACGGGGCCCCAGAGGGCCAAGACGCAGAGAACAC GCAGGCAGTGCAACCCGAGGAGAGCCGTTCGGAAGGGAGAATCGGCTTCAAGGCCTACAAGAATTACTTC TCGGCGGGCGCATCCTGGTTCTTCATCATTTTCCTTGTGCTGCTTAACATGGTGGGCCAGGTTTTCTATG TTCTTCAGGACTGGTGGCTTTCCCACTGGGCGAACAAGCAAGGTGCACTGAACAACACCAGAAATGCGAA TGGAAATATAACGGAGACCCTAGACCTCAGCTGGTACTTAGGAATTTACGCAGGTCTAACTGCGGTCACC GTCCTTTTTGGCATAGCGAGATCCCTACTGGTGTTCTATATCCTTGTGAACGCTTCCCAGACTTTGCACA ACAGGATGTTTGAGTCCATACTGAAGGCTCCCGTGTTGTTCTTCGACAGAAATCCAATCGGGAGGATTTT AAATCGTTTCTCCAAAGACATCGGACACATGGATGATTTGCTTCCCCTGACGTTCCTGGACTTCATCCAG ACGTTGCTCCTCGTCGTAAGTGTGATCGCTGTGGCCGCGGCCGTGATCCCTTGGATCCTCATACCATTGG TTCCGCTCTCAGTCGTCTTCCTGGTTCTTCGGAGATACTTCTTAGAGACGTCACGGGATGTCAAGCGCCT GGAATCCACAACACGGAGCCCGGTATTCTCCCATTTATCGTCCTCCCTCCAGGGACTCTGGACCATCCGG GCTTACAAAGCTGAGGAGAGGTGTCAGGAGCTGTTTGATGCACACCAGGACTTGCATTCAGAGGCTTGGT TCTTGTTCCTGACGACATCGAGATGGTTCGCTGTGCGTCTGGACGCCATCTGCGCCATCTTTGTAATCGT CGTTGCCTTCGGGTCCCTTGTTCTGGCGAAGACTTTGAATGCTGGGCAGGTTGGCCTGGCCTTGTCCTAC GCCCTCACACTCATGGGGATGTTCCAGTGGTCTGTGCGACAGAGCGCCGAAGTAGAGAATATGATGATTT CAGTGGAGAGAGTGATTGAGTACACGGACCTAGAGAAGGAGGCGCCTTGGGAGTGCAAGAAGCGCCCACC CCCAGGCTGGCCCCACGAGGGAGTCATCGTCTTCGACAATGTGAACTTCACCTACAGCTTAGATGGGCCT CTGGTTCTGAAGCACCTGACTGCGCTCATCAAGTCCAGGGAAAAGGTTGGAATTGTGGGCAGAACCGGAG CTGGGAAAAGCTCCCTCATCTCGGCCCTCTTCAGGCTGTCAGAACCCGAGGGGAAAATCTGGATCGATAA GATCTTGACAACCGAAATTGGGCTTCACGACTTAAGGAAGAAAATGTCAATCATACCACAGGAACCTGTT CTGTTCACTGGAACCATGAGGAAAAACCTGGACCCCTTCAATGAGCACACGGACGAGGAGCTGTGGAGGG CCTTGGAGGAGGTACAACTTAAAGAGGCCATTGAAGATCTTCCTGGAAAAATGGATACTGAATTAGCAGA ATCTGGATCCAATTTCAGTGTTGGACAGAGACAGTTAGTGTGCCTTGCAAGGGCCATTCTAAAGAATAAC CGAATACTGATCATTGATGAAGCAACTGCAAATGTGGACCCAAGAACGGATGAGTTAATACAACAGAAGA TCCGGGAGAAGTTTGCCCAGTGCACAGTGCTCACCATTGCTCACAGACTGAACACCATCATTGACAGTGA CAAGATAATGGTTTTGGATTCAGGAAGACTGAAAGAATATGATGAGCCGTATGTCTTGCTGCAGAATCCA GAGAGCCTCTTTTACAAGATGGTTCAGCAACTGGGCAAGGGCGAAGCCGCTGCCCTCACCGAAACAGCAA AACAGGTATACTTCAGACGGAATTACCCAGATATTACATTCACCAGCCCCGCGGTTATGAACACCTCCAA TGGACAGCCCTCGGCCTTAACAATATTTGAAACAGCATTGTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001163676 |
| Insert Size | 3753 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001163676.1, NP_001157148.1 |
| RefSeq Size | 5504 bp |
| RefSeq ORF | 3753 bp |
| Locus ID | 239273 |
| Gene Summary | ATP-dependent transporter of the ATP-binding cassette (ABC) family that actively extrudes physiological compounds and xenobiotics from cells. Transports a range of endogenous molecules that have a key role in cellular communication and signaling, including cyclic nucleotides such as cyclic AMP (cAMP) and cyclic GMP (cGMP), bile acids, steroid conjugates, urate, and prostaglandins. Mediates also the ATP-dependent efflux of glutathione conjugates such as leukotriene C4 (LTC4) and leukotriene B4 (LTB4). The presence of GSH is necessary for the ATP-dependent transport of LTB4, whereas GSH is not required for the transport of LTC4. Mediates the cotransport of bile acids with reduced glutathione (GSH). Transports a wide range of drugs and their metabolites, including anticancer, antiviral and antibiotics molecules (Probable). Confers resistance to anticancer agents (Probable).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (3) lacks an in-frame exon in the coding region, compared to variant 1. The encoded isoform (2) is shorter, compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG215261 | Abcc4 (tGFP-tagged) - Mouse ATP-binding cassette sub-family C (CFTR/MRP) member 4 (Abcc4) transcript variant 3, (10ug) |
CNY 13,680.00 |
|
| MR215261 | Abcc4 (Myc-DDK-tagged) - Mouse ATP-binding cassette, sub-family C (CFTR/MRP), member 4 (Abcc4), transcript variant 3 |
CNY 12,450.00 |
|
| MR215261L3 | Lenti ORF clone of Abcc4 (Myc-DDK-tagged) - Mouse ATP-binding cassette, sub-family C (CFTR/MRP), member 4 (Abcc4), transcript variant 3 |
CNY 14,350.00 |
|
| MR215261L4 | Lenti ORF clone of Abcc4 (mGFP-tagged) - Mouse ATP-binding cassette, sub-family C (CFTR/MRP), member 4 (Abcc4), transcript variant 3 |
CNY 14,350.00 |
