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Cilp (NM_173385) Mouse Untagged Clone
CAT＃: MC224053
Cilp (untagged) - Mouse cartilage intermediate layer protein, nucleotide pyrophosphohydrolase (Cilp), (10ug)
CNY 16,060.00
货期*
7周
规格
Product images
经常一起买 (3)
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 9830114D16; C130036G17Rik |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC224053 representing NM_173385
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCAGCAATCAAGACTTGGGTATTCTCTTTCCTGGTCCTTGAGGTCACCACCGTGCTGGGGAGACAGA CGATGCTTGCCCAGTCAGTGAGAAGAGTCCAGCCTGTGAAGAGGACCCCCAAGACCCTTGCCAAGCCTGC CGACTCCCAGGAGAGTCCCGGAGAGTGGACAACATGGTTTAACATCGACCACCCAGGTGGGCAGGGTGAC TATGAGCGGCTGGATGCCATTCGCTTCTACTATGGGGAGCGTGTGTGTGCCCGTCCCCTGCGGCTAGAGG CCCGGACCACTGACTGGATGCCTGCGGGCAGCACTGGCCAGGTGGTCCACGGCAGTCCCCGTGAGGGCTT CTGGTGCCTCAACAGGGAGCAGAGACCAGGCCAGAACTGTTCCAATTATACCGTGCGCTTCCTCTGCCCA CCAGGGTCCTTGCGAGGAGATGCAGAGCACATCTGGAGTTCCTGGTCTCCCTGGAGCAAGTGCTCAGCTG CCTGCGGTCACACTGGGGTGCAGACCCGTACCCGCACCTGCTTGGCACAGACAGTGTCACTGTGCAGTGA GGCGACCGAGGAGGGCCAGCTCTGCATGAGCCAGGCCTGCACAGCTTGTGACCTGACCTGCCCCATGGGC CAGGTAAATGCTGACTGTGATGCCTGCATGTGCCAGGACTTCATGCTTCACGGGGCCATCTCCCTCCCTG GAGGTGGCCCAGCTCCAGGAGCCGCTGTCTACCTGCTGGCCAAGGCACCAAAGATGCTGACCCGAACAGA CAGCAGCGGGAGGTTCCGAGTTCCTGGCTTGTGTCCTGATGGCAAAACCATCCTGAAAATCACCAAGACC AAGTTTGCCCCAATTATGATCACGATGCCCAAGACTAGCCTGAAGTCAGCTACCATCAATGCGGAGTTTG TGAGGGCAGAGACCCCATACATTGTAATGAACCCTGAGATGAAAGCACGTCGGGCTGGGCAGAGTGTGTC TCTGTGCTGCAAAGCCACGGGGAAACCCAGTCCGGACAAGTACTTCTGGTACCACAACAACACACTGCTG GATCCCTCCCTCTATAAGCACGAGAGCAAGCTGGTGCTGAGGAACCTGCAGCAGGACCAAGCAGGGGAGT ACTTCTGTAAGGCTCAGAGTGATGCTGGGGCTGTGAAGTCCAAGGTCACCCAGCTCACTGTCATTGCACA TGATGAGACTCCTTGCAACCCAACCCCAGAGAGCTACCTTATCCGGCTGCCCCATGACTGCTTTCAGAAC GCCAGCAATTCCTTCTACTACGACGTAGGCCGCTGCCCGATCAAGACCTGTGCAGGGCAGCAGGACAATG GGATCCGGTGCCGAGATGCTGTGGAGAACTGCTGCGGCATTTCCAGAACAGAAGAGAGGGAGATCCAGTG CAGTGGGTACACACTGCCCACCAAGGTGGCTGTGGAGTGCAGCTGCCAACGATGCGCAGAGACACGGAGC ATCGTCCGGGGCCGAGTCACTGCTGCTGACAACGGGGAGCCCATGCGCTTTGGCCATGTGTACATGGGGA ATAACCGCGTGAGCATGACTGGCTACAAAGGCACCTTCACACTCCACATCCCCCAGGACACGGAGAGGCT GGTGCTCACATTTGTGGACAGGCTGCAGAAGTTTGTCAACACAACCAAAGTGCTGCCCTTCAACAAGAAG GGAAGCGCAGTGTTCCACGAGATCAAGATGCTTCGGCAGAAAGAGCCCATCACGTTGGAAGCCATGGAGA CCAACATTATCCCCCTGGGAGAGGTGATTGGTGAAGACCCTGTGGCTGAGCTGGAGATCCCATCCAAAAG TTTCTATAGGCAGAACGGGGAGCCCTTCACAGGAAAGGTAAAGGCCAGCGTGACCTTCCTGGATCCTCGG AACATCTCGACGGCCACAGCTGCCCAAAGTGACCTCAACTTCATCAATGATGAAGGAGACACTTTTCCCC TTAGAACATATGGTATGTTTTCAGTGGACTTTAGAGATGAGGCCACTTCCGAGTCACTTAATGCTGGCAA GGTGAAGGTCCACCTTGACTCGACCCAGGTCAAAATGCCAGAGCATGTGCCAGCCATGAAACTCTGGTCG CTCAACCCAGACACAGGACTGTGGGAAGAGGAAGGGGATTTCAAGTTTGAAAGCCAAAGGAGGAACAAGA GGGAAGAGAGAACCTTCCTAGTGGGCAATATGGAGATCCGGGAGAGAAGGCTCTTTAACCTGGACGTCCC TGAAAGCCGAAGGTGCTTCATTAAGGTGAGGACTTACCGGAGTGAGAGGTTCCTGCCCAGTGAGCAAATT CAGGGAGTTGTGGTCTCAGTGATCAATCTGGAGCCCAGAACTGGCTTCTCATCTAACCCCAGGGCCTGGG GCCGATTTGACAGTGTCATCACAGGGCCCAATGGGGCCTGCCTGCCTGCCTTCTGTGATGATCAGTCCCC CGATGCTTACTCTGTCTATGTCTTGGCAAGCCTTTCTGGAGAAGAACTAGAGGCAGTTGAGTCTTCTCCT AAATTCAACCCAAATGCAATCGGTGTCCCTCAGCCTTACCTCAACAAACTTAAATACCGTCGGACAGACC ATGAGGATCCACGGGTTAAAAAGACGGCTTTCCAAATCAGTATGGCCAAACCAAGGCCCAACTCAGCTGA GGAGAGCAATGGGCCTATCTATGCCTTTGAGAACCTTCGGGCGTGTGAGGAGGCACCCCCCAGTGCAGCT CACTTCCGGTTCTATCAGATCGAGGGGGATCGCTATGACTATAACACAGTTCCTTTCAATGAAGATGACC CTATGAGCTGGACTGAAGACTACCTGGCATGGTGGCCCAAGCCAATGGAGTTCAGGGCCTGCTATATCAA GGTTAAGATTGTGGGGCCACTGGAGGTGAATGTACGATCCCGTAACATGGGAGGCACCCACCGGCAGACT GTGGGGAAGCTCTATGGGATCCGGGATGTGAAGAGTACTCGGGACAGAGACCAACCTAATGTCTCATCTG CCTGCCTGGAGTTCAAGTGCAGTGGAATGCTGTATGACCAAGACCGTGTAGACCGCACATTAGTAAAGGT TATCCCCCAGGGCAGCTGCCATCGAGCTAGTGTTAACTCTATGTTGCACGAGTACCTGGTCAACCACCTT CCCCTGGCAGTCAACAATGACACCAGCGAGTATACTATGCTGGCACCCCTGGACCCTCTGGGCCACAATT ACGGTATCTATACTGTTACTGATCAGGACCCTCGTACAGCTAAGGAGATTGCGCTCGGCCGGTGCTTTGA TGGCACTTCCGATGGCTCCTCCAGAATCATGAAGAGCAATGTGGGAGTTGCCCTGACCTTTAACTGTGCA GAAAGGCAGGTAGGCCGCCAGAGTGCCTTCCAGTACCTCCAAAGCACACCGGCCAGGTCCCCAGCTACAG GCACTGTCCAAGGAAGAGTACCAGCCATGAGGCAACAACGGGCAAGCAGGGGTGGCCTACGCCGGCGTGG AAGCATGGGCCCCTCTGAGATTTTCTGGTGTTGCTCAACAACCTCTGAGCAACTAAGTCTTGTGGTTCTT AGTCCTTTCTGTCCATCTCATGTGACAGCTGTCGTGAGACTGATGCACAGACTGTCACTTGTTAATTTAA ACATATCTGGTTTGGTGCAGTTTGTTTCTTTGTGCCTTTACTTACTGTCTCTGCCTCATGATGCTGATTG CCACAGGGCCCCCACGATGACAAAACAAAGATTCTCCTCTTAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_173385 |
| Insert Size | 3753 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_173385.2, NP_775561.1 |
| RefSeq Size | 4153 bp |
| RefSeq ORF | 3753 bp |
| Locus ID | 214425 |
| UniProt ID | Q66K08 |
| Gene Summary | Probably plays a role in cartilage scaffolding. May act by antagonizing TGF-beta1 (TGFB1) and IGF1 functions. Has the ability to suppress IGF1-induced proliferation and sulfated proteoglycan synthesis, and inhibits ligand-induced IGF1R autophosphorylation. May inhibit TGFB1-mediated induction of cartilage matrix genes via its interaction with TGFB1. Overexpression may lead to impair chondrocyte growth and matrix repair and indirectly promote inorganic pyrophosphate (PPi) supersaturation in aging and osteoarthritis cartilage (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MR211772 | Cilp (Myc-DDK-tagged) - Mouse cartilage intermediate layer protein, nucleotide pyrophosphohydrolase (Cilp) |
CNY 8,248.00 |
|
| MR211772L3 | Lenti ORF clone of Cilp (Myc-DDK-tagged) - Mouse cartilage intermediate layer protein, nucleotide pyrophosphohydrolase (Cilp) |
CNY 12,830.00 |
|
| MR211772L4 | Lenti ORF clone of Cilp (mGFP-tagged) - Mouse cartilage intermediate layer protein, nucleotide pyrophosphohydrolase (Cilp) |
CNY 12,830.00 |
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