Kdm2a (NM_001001984) Mouse Untagged Clone

CAT#: MC223755

Kdm2a (untagged) - Mouse lysine (K)-specific demethylase 2A (Kdm2a), (10ug)



  "NM_001001984" in other vectors (3)

CNY 14,920.00


货期*
7周

规格
    • 10 ug

Product images

经常一起买 (3)
TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Mouse Untagged Clone
Tag Tag Free
Synonyms 5530401A10Rik; 100043628; AA589516; AW536790; Cxxc8; Fbl7; Fbl11; Fbxl11; Gm4560; Jhdm1
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>MC223755 representing NM_001001984
Red=Cloning site Blue=ORF Orange=Stop codon

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGGAACCTGAAGAAGAAAGGATTCGGTACAGCCAGAGATTGCGTGGTACCATGCGTCGTCGCTATGAAG
ATGATGGCATTTCAGATGATGAAATTGAAGGGAAAAGAACTTTTGACTTGGAAGAGAAGCTCCAAACCAA
CAAATATAATGCCAATTTTGTTACTTTTATGGAGGGAAAAGATTTTAATGTAGAGTATATCCAGCGGGGT
GGCTTGAGAGACCCTCTCATTTTCAAGAATTCTGATGGACTTGGAATAAAGATGCCGGATCCAGACTTCA
CAGTGAATGATGTCAAAATGTGTGTGGGGAGTCGTCGGATGGTGGATGTCATGGATGTGAACACACAGAA
GGGGATTGAAATGACCATGGCACAATGGACACGATACTATGAGACTCCAGAGGAAGAGCGAGAAAAACTC
TATAATGTTATCAGCCTAGAGTTTAGCCACACCAGGCTTGAGAATATGGTGCAGCGGCCTTCCACGGTGG
ATTTCATTGACTGGGTAGATAACATGTGGCCAAGGCACTTGAAAGAAAGTCAGACAGAATCAACAAATGC
CATCTTAGAGATGCAGTACCCTAAAGTGCAAAAGTACTGTCTAATGAGTGTTCGAGGCTGCTATACTGAC
TTCCATGTGGATTTTGGAGGTACTTCTGTTTGGTATCACATCCACCAAGGTGGAAAGGTCTTCTGGCTCA
TCCCCCCTACAGCCCACAACCTGGAGCTGTACGAGAATTGGCTGCTATCAGGGAAACAGGGAGACATCTT
TCTGGGTGACCGGGTGTCAGATTGCCAACGAATTGAGCTCAAGCAGGGCTATACCTTCGTTATTCCCTCA
GGTTGGATTCATGCTGTGTATACTCCTACAGACACATTAGTGTTTGGAGGCAATTTTTTGCATAGCTTCA
ACATCCCCATGCAATTAAAGATATACAGCATTGAAGATCGAACACGGGTTCCAAATAAATTCCGTTACCC
ATTTTACTATGAAATGTGTTGGTATGTGTTGGAGCGCTATGTATACTGCATAACCAACCGATCCCACCTA
ACTAAGGATTTTCAGAAAGAATCCCTTAGCATGGATATGGAGTTAAATGAGTTGGAGTCTGGAAATGGTG
ATGAGGAAGGGGTGGACAGAGAAGCCCGACGCATGAACAATAAGCGATCTGTGCTTACCAGCCCTGTTGC
TAATGGAGTGAACCTGGATTACGATGGACTTGGCAAAGCCTGCCGAAGTCTTCCAAGTCTGAAGAAAACT
TTGTCTGGAGACTCATCCTCAGACTCTACCCGGGGATCCCACAATGGCCAAGTTTGGGATCCCCAATGTA
GCCCTAAAAAGGATAGGCAAGTGCATCTCACCCATTTTGAACTTGAAGGTCTTCGATGTCTTGTAGATAA
GTTAGAGTCACTGCCACTGCACAAGAAGTGTGTCCCCACAGGAATAGAAGACGAAGATGCTCTGATTGCT
GATGTAAAGATTTTGCTGGAAGAACTTGCCAGTAGCGATCCCAAGTTAGCCCTCACTGGAGTCCCTATAG
TACAGTGGCCAAAAAGGGATAAGCTTAAATTCCCTACCAGGCCAAAGGTGAGGGTTCCTACAATTCCCAT
CACAAAGCCTCACACCATGAAGCCAGCTCCACGCTTAACACCTGTAAGGCCTGCTGCAGCCTCCCCCATT
GTGTCAGGAGCCAGGCGGAGAAGAGTGCGGTGCAGGAAATGCAAAGCTTGTGTGCAAGGAGAATGTGGAG
TCTGCCACTACTGCAGGGACATGAAGAAATTTGGTGGACCTGGACGCATGAAGCAATCCTGTGTCCTCCG
ACAGTGCTTAGCACCCAGACTGCCTCATTCAGTTACGTGTTCTCTCTGTGGAGAAGTAGATCAGAATGAA
GAGACCCAGGACTTTGAAAAGAAACTCATGGAATGCTGCATCTGCAACGAGATAGTTCATCCTGGCTGCC
TCCAGATGGATGGAGAGGGGTTGCTGAACGAGGAATTGCCAAATTGCTGGGAGTGTCCAAAGTGTTACCA
GGAAGACAGCTCGGACAAAGCCCAGAAGCGGAAAATAGAAGAGAGTGATGAAGAAGCTGTACAAGCCAAA
GTCTTACGGCCCCTGAGGAGCTGCGAGGAGCCTCTCACACCCCCGCCTCACTCACCTACTTCCATGCTGC
AGCTCATCCACGACCCGGTTTCTCCCCGGGGTATGGTGACTCGGTCATCCCCTGGGGCTGGCCCCAGCGA
CCACCACAGTGCCAGCCGTGATGAACGCTTCAAACGGCGGCAGTTGCTGCGGCTACAAGCCACCGAGCGC
ACCATGGTACGGGAAAAGGAGAACAATCCCAGCGGCAAAAAGGAGCTGTCTGAAGTTGAGAAAGCCAAGA
TCCGGGGATCGTACCTCACTGTCACTCTACAGAGGCCCACCAAAGAGCTCCACGGGACATCCATTGTGCC
CAAGCTGCAGGCCATCACGGCCTCCTCTGCCAACCTTCGCCCTAACCCCCGCGTGCTAATGCAGCACTGC
CCAGCCCGAAACCCCCAGCATGGGGATGAGGAGGGGCTTGGGGGAGAGGAGGAGGAAGAGGAGGAGGAGG
AGGAAGATGACAGTGCAGAGGAGGGGGGTGCAGCCAGGCTGAATGGCCGGGGCAGTTGGGCTCAGGATGG
AGACGAAAGCTGGATGCAGCGGGAGGTCTGGATGTCTGTCTTCCGCTACCTCAGCCGCAAAGAACTTTGT
GAATGTATGCGAGTGTGCAAGACATGGTATAAATGGTGCTGTGATAAACGACTTTGGACAAAAATTGACT
TGAGTAGGTGTAAGGCCATCGTACCACAAGCTCTCAGTGGTATCATCAAGCGGCAGCCAGTAAGCCTCGA
CCTCAGCTGGACTAACATCTCCAAAAAGCAGCTGACATGGCTGGTCAATAGGCTGCCAGGATTAAAAGAC
CTCCTCCTAGCAGGCTGTTCCTGGTCTGCAGTATCTGCCCTCAGCACTTCCAGCTGCCCGCTTCTCAGGA
CCCTTGATCTTCGGTGGGCAGTAGGAATTAAAGACCCTCAAATTCGGGACTTGCTGACTCCACCCACAGA
TAAGCCAGGTCAAGACAATCGAAGCAAACTCCGGAACATGACTGACTTCCGGCTGGCAGGCCTTGACATC
ACAGATGCTACTCTCCGACTCATCATTCGCCACATGCCCCTTTTGTCTCGACTTGACCTCAGTCACTGCA
GTCACCTTACAGATCAGTCCTCCAACCTACTAACTGCTGTCGGGTCTTCCACTCGATACTCCCTTACAGA
GCTCAATATGGCAGGTTGCAATAAATTGACAGACCAGACCCTGTTCTTCCTAAGGCGAATTGCTAATGTC
ACCTTGATTGACCTTCGAGGATGCAAACAGATCACGAGAAAAGCCTGTGAGCACTTCATCTCAGACTTGT
CCATCAACAGCCTCTACTGCCTGTCTGATGAGAAACTGATACAGAAGATTAGCTAA


ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
ACAAGGATGACGACGATAAGGTTTAA
Restriction Sites SgfI-MluI     
ACCN NM_001001984
Insert Size 3486 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_001001984.2, NP_001001984.2
RefSeq Size 7268 bp
RefSeq ORF 3486 bp
Locus ID 225876
UniProt ID P59997
Gene Summary Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and tri-methylated H3 'Lys-36'. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at the centromere. Required to sustain centromeric integrity and genomic stability, particularly during mitosis (By similarity). Regulates circadian gene expression by repressing the transcriptional activator activity of CLOCK-ARNTL/BMAL1 heterodimer and RORA in a catalytically-independent manner (By similarity).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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