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Ipo8 (NM_001081113) Mouse Untagged Clone
CAT＃: MC223193
Ipo8 (untagged) - Mouse importin 8 (Ipo8), (10ug)
CNY 13,020.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 6230418K12Rik; Abcc10; C130009K11Rik; MRP7; OM-1; Om1; Ranbp8 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC223193 representing NM_001081113
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGACCTCAATCGGATCATCCAGGCGCTGAAGGGCACTATCGACCCAAAGCTGAGAATTGCAGCTGAGA CGGAGCTTAACCAGTCCTACAAGATTATTAATTTTGCCCCCAGCTTGCTTCGGATCATAGTCTCTGACCA TGTGGAGTTCCCTGTGCGTCAGGCAGCTGCCATCTACCTGAAGAACATGGTGACACAATACTGGCCAGAC AGGGAGCCTCCACCAGGAGAAGTGATATTTCCATTCAATATTCATGAGAACGACCGGCAGCAGATCCGTG ACAACATTGTGGAAGGGATAATTCGGTCTCCAGATTTGGTGAGAGTCCAGTTAACAATGTGTCTCCGAGT CATCATTAGACACGATTTTCCTGGTCACTGGCCTGCAGTGGTCGACAAGATAGACTACTACTTGCAGTCA CCAAACAGTGGGAGCTGGCTTGGCAGTTTACTGTGCTTATATCAGCTGGTGAAGACATATGAATATAAAA AAGCAGAAGAAAGAGAACCTCTCCTGGCAGCCATGCAGATATTTCTGCCTAGAATTCAACAGCAAATCCT GCAGCTGCTTCCGGATGCCTCCCATTACTCTGTGTTGCTGCAGAAACAGATTCTGAAAATATTCTATGCT CTCGTTCAGTATGCACTGCCTCTTCAGCTGGTGAATCACCAGACCATGACAACGTGGATGGAGATCTTTC GGACCATCATTGATAGGACGGTCCCTCCGGAGACTCTTCAGATTGATGAGGATGACCGGCCAGAGCTGGT GTGGTGGAAGTGTAAGAAGTGGGCTCTGCACATTGTCGCTCGTCTCTTTGAACGGTATGGAAGCCCAGGA AATGTCACAAAAGAATACTTCGAATTTTCTGAATTTTTTTTGAAAACCTATGCAGTGGGAATTCAACAGG TACTACTAAAAATTTTAGACCAATACAGACAGAAAGAGTATATAGCCCCCCGTGTTCTTCAGCAAGCTTT CAACTATCTAAACCAAGGGGTTGTCCATGCTGTGACTTGGAAGCAGATGAAGCCACATATACAGAATATC TCTGAAGATGTGATTTTTTCTGTGATGTGTTATAAAGACGAGGATGAAGAGCTGTGGCAAGAAGATCCGT ATGAATACATAAGGATGAAATTTGATATTTTCGAAGATTATGCTTCTCCTACCACAGCGGCCCAGACCCT CTTGTATACAGCTGCAAAGAAAAGAAAAGAGGTGTTGCCAAAAATGATGGCGTTCTGTTATCAGATACTA ACAGACCCGAACTTTGACCCTAGGAAGAAAGATGGAGCCCTGCATGTGATTGGTTCCCTGGCTGAGATTT TGTTGAAGAAGAGTTTATTCAAGGACCAAATTGAGCTGTTCCTGCAGAATCATGTATTTCCATTATTAAT GTCTAACCTGGGATATCTTCGAGCTAGATCCTGCTGGGTGCTGCATGCATTTAGTTCTTTGAAGTTTCAC AATGAGCTCAACCTCAGAAATGCAGTAGAATTAGCCAAGAAGAGCCTGATTGAAGACGAGGAGATGCCTG TCAAGGTGGAAGCTGCCCTTGCACTGCAGTCGCTGATCTCCAACCAGGCACAAGCCAAGGAGCACATGAA ACCGTACGTGAGATTCATCATGCAGGAGCTGCTGCATATCGTCAGAGAGACGGAGAATGACGATGTTACC AATGTCATCCAGAAGCTCATATGTGAGTACAGTCAGGACGTGGCCTCCATCGCTGTCGACACAACCCAGC ACTTGGCTGAGATATTTGGTAAAGTTCTTCAGAGTGATGAGTATGAAGAAATTGAAGACAAAACTGTCAT GGCCATGGGGATTTTACACACCATCGACACTATCTTAACAGTTGTGGAAGATCATCCAGAGATTATACAG CAGTTGGAGAACATCTGCCTACGAATCATTGATCTTGTTTTACAGAAGCACGTTATTGAATTCTATGAGG AAATCCTTTCCCTGGCATACAATTTAACCTGCCATACCATCTCCCCGCAGATGTGGCAGCTCCTGGGCAT TTTATATGAAGTTTTCCAGCAGGATTGCTTCGAGTACTTTACAGACATGATGCCTCTCCTGCATAATTAC GTGACAGTAGATACCAACGCTCTGCTGTCAAATCCAAAGCATTTAGAAGTCTTGTTCACAATGTGCAGGA AGGTACTGTGTGGAGAGGCAGGAGAAGATGCCGAGTGCTATGCTGCAAAACTCTTGGAAGTCATCATTCT TCAGTGCAAAGGAAGGGGAATTGACCAGTGTATCCCGCTATTCATTCAACTTGTCTTGGAGAGATTAACA CGTGGGGTCAAGACCAGTGAGCTGCGCACAATGTGTCTCCAGGTGGCCATCGCAGCTCTTTACTACAGCC CTGAACTGCTGTTCCATACACTGGAGCAAGTCCAGCTGCCACACAACCCAGGACCCGTCACGTCGCAGTT CATAAACCAGTGGATGAATGACACTGATTACTTCCTGGGACACCATGACCGGAAGATGTGTATAATAGGA CTGAGTGTGCTCTTGGAGCTGCAGAACCGACCTCCTGCCGTGGATGCTGTGGCTGCACAGATCCTCCCCT CCATTCTCTTCCTTTTCCTTGGCCTGAAGCAGGTCTGTGCTACACGACAAACGGTAAACCGTGAAAATCA CTCAAAAGCAGAGAAAGTCGACATAGAGGAAAATGAGGAGATTTCAAGTGAGGAGGAGGAAGAGACAAGT GTGAGTGCTCAAGCTATGCAGTCACAAATTGGCAGAAGTGAGGAGGAGGATGATGACGACTGGGATGAAG AAGTGCTGGAGGAGACAGCCCTCGAGGGCTTCAGCACCCCACTGGACCTGGACAACAGTGTGGATGAATA CCAGTTTTTTACACAAGCTCTGCTGACTGTGCAGAATCGGGATGCTGCCTGGTACCAGCTGCTGGTGGCA CCACTCAGTGAGGATCAGAAAAGAAAGCTGCAGGAGGTGTACACGTTGGCAGAGCACCGAAGGACACTGG CAGCAGGGCAGTTTCACATTTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001081113 |
| Insert Size | 3033 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001081113.1, NP_001074582.1 |
| RefSeq Size | 5359 bp |
| RefSeq ORF | 3033 bp |
| Locus ID | 320727 |
| UniProt ID | Q7TMY7 |
| Gene Summary | Seems to function in nuclear protein import, either by acting as autonomous nuclear transport receptor or as an adapter-like protein in association with the importin-beta subunit KPNB1. Acting autonomously, is thought to serve itself as receptor for nuclear localization signals (NLS) and to promote translocation of import substrates through the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. In vitro mediates the nuclear import of SRP19 (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG223262 | Ipo8 (tGFP-tagged) - Mouse importin 8 (Ipo8), (10ug) |
CNY 9,220.00 |
|
| MR223262 | Ipo8 (Myc-DDK-tagged) - Mouse importin 8 (Ipo8) |
CNY 7,032.00 |
|
| MR223262L3 | Lenti ORF clone of Ipo8 (Myc-DDK-tagged) - Mouse importin 8 (Ipo8) |
CNY 10,260.00 |
|
| MR223262L4 | Lenti ORF clone of Ipo8 (mGFP-tagged) - Mouse importin 8 (Ipo8) |
CNY 10,260.00 |
