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Epha8 (NM_007939) Mouse Untagged Clone
CAT＃: MC223170
Epha8 (untagged) - Mouse Eph receptor A8 (Epha8), (10ug)
CNY 13,020.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | AW047546; Eek; Hek3; mKIAA1459 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC223170 representing NM_007939
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCCCCCGCCCGGGCCCGCCTGTCCCCCGCTCTCTGGGTCGTCACGGCCGCGGCGGCGGCCACCTGCG TGTCCGCGGGGCGCGGCGAAGTGAACTTGTTGGATACATCAACCATCCACGGAGACTGGGGCTGGCTCAC GTATCCCGCTCATGGGTGGGACTCCATCAACGAGGTAGACGAGTCCTTCCGGCCCATCCACACGTACCAA GTATGCAACGTCATGAGCCCCAACCAGAACAACTGGCTGCGCACGAACTGGGTGCCCCGCGACGGCGCCA GGCGTGTCTACGCCGAGATCAAATTCACCCTGCGTGACTGCAATAGCATCCCAGGGGTGTTAGGTACCTG CAAGGAGACCTTCAACCTTCACTACCTGGAGTCTGACCGCGACCTGGGGGCCAGCACACAAGAGAGCCAG TTCCTCAAGATTGACACCATCGCGGCGGATGAGAGCTTCACGGGCGCAGACCTGGGTGTGCGGAGGCTCA AGCTGAACACGGAGGTGCGTGGCGTGGGCCCGCTCAGCAAGCGCGGCTTCTACCTGGCCTTCCAGGACAT AGGTGCCTGCCTCGCCATCCTCTCACTCCGAATCTACTACAAGAAGTGCCCCGCCATGGTACGCAACCTG GCAGCCTTCTCGGAGGCGGTTACTGGGGCCGACTCGTCCTCGCTGGTTGAGGTTCGAGGCCAGTGTGTGC GGCACTCGGAAGAGCGCGACACACCCAAGATGTACTGCAGTGCTGAGGGCGAATGGCTGGTGCCCATCGG CAAGTGCGTGTGCAGTGCTGGCTATGAGGAGCGGCGGGATGCCTGCATGGCCTGTGAGCTGGGCTTCTAC AAGTCAGCCCCCGGGGACCAGCTGTGCGCCCGATGCCCACCCCACAGCCACTCTGCCACCCCTGCGGCCC AGACCTGCCGTTGTGACCTCAGCTACTACCGCGCGGCCTTGGACCCACCATCGGCAGCCTGCACCCGGCC ACCCTCAGCACCAGTGAACCTGATCTCCAGCGTAAATGGAACGTCTGTGACCCTCGAGTGGGCCCCTCCT CTGGACCCAGGTGGTCGCAGCGACATCACCTACAACGCAGTGTGCCGCCGCTGCCCCTGGGCCCTGAGCC ACTGTGAGGCTTGTGGGAGTGGAACTCGCTTCGTCCCGCAGCAGACAAGCCTGGCACAGGCCAGCCTGCT GGTGGCCAACCTGCTAGCCCACATGAACTACTCCTTCTGGATCGAGGCAGTCAACGGTGTCTCCAACCTG AGCCCTGAGCCCCGCAGCGCTGCTGTGGTCAACATCACCACGAACCAGGCAGCCCCGTCCCAGGTGGTGG TGATCCGGCAGGAGCGGGCTGGGCAGACCAGCGTGTCACTCCTGTGGCAGGAACCAGAGCAGCCCAACGG CATCATTCTGGAGTACGAGATCAAGTACTACGAGAAGGATAAGGAGATGCAAAGTTACTCTACCCTCAAG GCTGTCACCACCCGCGCCACCGTGTCAGGCCTCAAACCAGGCACTCGCTACGTGTTCCAGGTCCGAGCCC GCACCTCAGCAGGCTGTGGCCGCTTCAGCCAGGCCATGGAGGTGGAGACCGGGAAACCCAGGCCCCGCTA CGACACTCGGACCATCGTCTGGATCTGCCTGACACTCATCACGGGCCTGGTGGTGCTCCTCTTGCTTCTC ATCTGCAAGAAGAGGCACTGTGGCTACAGCAAGGCGTTCCAGGACTCGGATGAAGAGAAGATGCATTACC AGAACGGGCAGGCACCCCCACCTGTCTTCTTGCCCTTGAACCACCCCCCGGGGAAGTTCCCAGAAACCCA GTTCTCTGCAGAGCCCCACACCTATGAGGAACCAGGTCGGGCAGGCCGGAGCTTTACCCGAGAGATCGAG GCATCCAGGATCCACATTGAGAAGATCATAGGCTCGGGGGAGTCAGGAGAAGTGTGCTATGGGAGGCTGC AGGTGCCAGGACAGCGCGATGTGCCTGTGGCCATCAAGGCTCTCAAAGCTGGCTACACGGAGAGACAGCG ACAAGACTTCTTGAGCGAGGCAGCCATCATGGGCCAATTTGATCACCCTAACATCATCCGCCTTGAGGGT GTGGTCACCCGTGGTCGCCTGGCAATGATTGTGACGGAGTACATGGAAAATGGCTCTCTGGATGCCTTCC TCAGGACCCACGATGGGCAGTTCACCATCGTGCAGCTAGTGGGCATGCTCAGAGGGGTGGGCGCTGGCAT GCGCTACCTCTCAGACCTGGGCTACATTCACCGTGACCTGGCTGCCCGCAATGTCCTGGTGGATGGCCGT CTGGTGTGCAAAGTGTCAGACTTTGGGCTCTCAAGGGCTCTGGAGGATGACCCCGAAGCTGCCTACACCA CTGCGGGAGGGAAGATCCCTATCCGATGGACAGCGCCGGAGGCCATTGCTTTCCGCACGTTCTCCTCAGC CAGTGATGTGTGGAGCTTTGGTGTGGTCATGTGGGAGGTTCTAGCCTATGGTGAACGACCCTACTGGAAC ATGACCAACCAGGATGTCATCAGCTCTGTGGAGGAGGGTTATAGGCTGCCAGCACCCATGGGTTGCCCAC GTGCCCTACACCAGCTCATGCTGGACTGCTGGCACAAGGACCGTGCCCAGCGGCCTCGCTTCGCTCATGT CGTGAGCGTTCTGGATGCCCTGGTCCACAGTCCTGAGAGCCTCAGGGCCACAGCCACAGTCAGCAGGTGC CCACCCCCTGCCTTCGCCAGGAGCTGCTTTGACCTCCGAGCAGGCGGAAGTGGGAACGGGGACCTCACAG TGGGGGACTGGCTGGACTCCATCCGAATGGGGCGCTACCGGGACCACTTCGCGGCTGGCGGGTACTCCTC CCTCGGCATGGTGCTTCGGATGAACGCCCAGGATGTGCGCGCCCTCGGCATCACTCTCATGGGTCACCAG AAGAAGATACTTGGAAGCATCCAGACCATGAGGGCCCAGCTGAGCAGCACCCAGGGACCCCGCCGGCACC TCTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_007939 |
| Insert Size | 3015 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_007939.2, NP_031965.2 |
| RefSeq Size | 4732 bp |
| RefSeq ORF | 3015 bp |
| Locus ID | 13842 |
| UniProt ID | O09127 |
| Gene Summary | Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. The GPI-anchored ephrin-A EFNA2, EFNA3, and EFNA5 are able to activate EPHA8 through phosphorylation. With EFNA5 may regulate integrin-mediated cell adhesion and migration on fibronectin substrate but also neurite outgrowth. During development of the nervous system plays also a role in axon guidance. Downstream effectors of the EPHA8 signaling pathway include FYN which promotes cell adhesion upon activation by EPHA8 and the MAP kinases in the stimulation of neurite outgrowth.[UniProtKB/Swiss-Prot Function] |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG226090 | Epha8 (tGFP-tagged) - Mouse Eph receptor A8 (Epha8), (10ug) |
CNY 8,592.00 |
|
| MR226090 | Epha8 (Myc-DDK-tagged) - Mouse Eph receptor A8 (Epha8) |
CNY 6,992.00 |
|
| MR226090L3 | Lenti ORF clone of Epha8 (Myc-DDK-tagged) - Mouse Eph receptor A8 (Epha8) |
CNY 10,260.00 |
|
| MR226090L4 | Lenti ORF clone of Epha8 (mGFP-tagged) - Mouse Eph receptor A8 (Epha8) |
CNY 10,260.00 |
