Ptpn4 (NM_019933) Mouse Untagged Clone
CAT#: MC222633
Ptpn4 (untagged) - Mouse protein tyrosine phosphatase, non-receptor type 4 (Ptpn4), (10ug)
CNY 11,880.00
Product images
Specifications
Product Data | |
Type | Mouse Untagged Clone |
Tag | Tag Free |
Synonyms | hPTP-MEG; Ptn4; PTPMEG; TEP; TEP/mPTPMEG |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>MC222633 representing NM_019933
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGACCGCACGTTTCCGATTGCCTGCTGGCAGAACCTACAATGTCCGAGCATCAGAGTTGGCCCGAGACA GACAGCATACAGAGGTCGTTTGCAACATTCTTCTTCTGGATAACACTGTACAGGCTTTCAGAGTTAACAA ACATGATCAGGGGCAAGTTCTGTTGGATATAGTCTTCAAGCATCTTGATTTGACTGAGCGAGACTATTTT GGTTTACAGTTGGCTGACGATTCCACAGATAACCCAAGGTGGCTGGATCCAAACAAACCAATAAGGAAGC AGCTAAAGAGAGGATCACCTTACAATTTGAACTTTAGAGTCAAATTCTTTGTAAGTGACCCCAACAAGTT ACAAGAAGAGTATACAAGGTATCAGTACTTTTTGCAAATTAAGCAAGACATTCTTACTGGAAGATTATCC TGTCCTTGTAACACTGCTGCCCTTTTAGCATCATTTGCTGTTCAGTCTGAACTTGGAGACTACAATCAGT CAGAAAACTTGGCAGGCTACCTCTCAGATTATTCTTTCATTCCTAATCAACCTCAAGATTTTGAGAAAGA AATTGCAAAGTTACATCAGCAGCACGTTGGCCTATCTCCTGCAGAAGCAGAATTTAATTACCTAAACGCG GCACGTACCTTAGAACTCTATGGAGTTGAATTTCACTATGCAAGGGATCAAAGTAACAATGAAATCCTGA TTGGAGTGATGTCAGGAGGAATTCTGATTTATAAGAACAGGGTACGGATGAATACTTTTCTGTGGTTGAA GATTGTAAAAATTTCTTTTAAATGCAAACAGTTTTTTATTCAACTTAGAAAAGAGTTGCATGAATCTAGA GAAACATTACTGGGATTTAATATGGTGAATTATAGAGCATGTAAAACTTTGTGGAAAGCGTGTGTAGAAC ATCATACATTCTTCCGCCTGGATAGACCACTTCCACCTCAAAAAAATTTTTTTGCACATTATTTTACATT GGGTTCCAAATTCCGGTACTGTGGGAGAACTGAAGTCCAGTCAGTTCAATATGGCAAAGAAAAGGCAAAT AAAGACAGGGTATTTGCAAGATCTCCAAGTAAGCCTTTGGCACGGAAATTAATGGATTGGGAAGTAGTCA GCAGAAATTCATTATCTGATGACAGGTTAGAAACACAAAGCCTCCCATCCCGGTCTCCACCTGGAACTCC CAACCATCGGAATTCTTCATTCACACAAGAGGCAACCCGGGTTCGGCCGTCTTCAGTTGGTCATTTGGTA GACCATGTGGTTCACATGTCCCCCAGTGAGGATTTTGTAAGTCAGAGATCTCCATCATCAACGCAAGCTA ATAGCATAGTTCTGGAGTCATCACCATCACAAGAGACCCCTGAAGATGGGCAGCCACCAGCTTTACCACC CAAACAATCTAAGAAAAATAGTTGGAACCAAATTCATTTTTCAAACTCTCAGCAAGATCTAGTCACCCAT ACTAATGAATCCTTTGATGTGCCCTCTTCCCCTGAAAAGTCCACTCCTAATGGTGGCATTCCACATGATA ACCTTGTTCTAATCAAAATGAAACCTGATGAAAATGGAAGGTTTGGATTCAATGTAAAGGGAGGATATGA TCAGAAGATGCCTGTAATTGTTTCCCGGGTAGCACCAGGAACACCTGCTGACCTCTGTGTCCCTCGCTTG AATGAAGGGGACCAAGTGGTACTAATAAATGGTCGGGACATTGCAGAACATACCCATGATCAAGTAGTCT TGTTTATTAAAGCTAGCTGTGAGAAACATTCTGGGGAACTCGTGCTCCTAGTCCGACCTAATGCTGTATA TGATGTAGTGGAAGAAAAACTAGAAAGTGAACCAGACTTCCAGTATATTCCTGAGAAAGCCCCACTAGAT AGTGTCCATCAAGATGACCATTCCTTGCGGGAGTCAATGATCCAGCTAGCTGAGGGGCTTATCACTGGAA CAGTACTGGCACAGTTTGATCAACTCTATCGGAAAAAACCTGGAATGACAATGTCTTGTGCCAAATTACC TCAGAACATTTCCAAAAACAGATACAGAGATATTTCACCTTATGATGCTACACGGGTCCTTTTAAAAGGT AATGAAGACTACATCAATGCAAACTATATAAATATGGAAATTCCTTCTTCAAGTATTATAAATCAATACA TTGCTTGTCAAGGGCCATTACCACACACTTGTAAAGATTTTTGGCAAATGACTTGGGAACAAGGCTCCTC CATGGTTGTGATGTTGACCACACAAGTTGAACGTGGCAGAGTTAAATGTCACCAGTATTGGCCAGAACCC TCAGAAAGCTCATCCTATGGATGCTATCAAGTCACCTGCCACTCTGAAGAAGGAAACCCTGCCTATATCT TCAGGAAGATGACACTGTTTAACCAAGAGAAAAATGAGAGCCGTCAACTTACTCAGATTCAGTACACAGC CTGGCCTGACCATGGAGTACCTGATGATTCGAGTGACTTTCTGGATTTTGTTTGTCATGTACGAGACCAG AGGGCTGGAAAAGAAGAGCCCATTATTGTTCATTGCAGTGCTGGAATTGGAAGGACTGGGGTTCTTATTA CTATGGAAACTGCCATGTGTCTCATTGAATGCAATCAGCCAGTTTATCCACTAGACATTGTAAGAACAAT GAGAGATCAAAGAGCAATGATGATCCAAACACCTAGTCAATACAGATTTGTATGTGAAGCTATTCTGAAA GTTTATGAAGAAGGATTTGTTAAACCATTAACAACATCATCAAATAAATAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
Restriction Sites | SgfI-MluI |
ACCN | NM_019933 |
Insert Size | 2781 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_019933.2, NP_064317.2 |
RefSeq Size | 4707 bp |
RefSeq ORF | 2781 bp |
Locus ID | 19258 |
UniProt ID | Q9WU22 |
Gene Summary | Phosphatase that plays a role in immunity, learning, synaptic plasticity or cell homeostasis (PubMed:17953619, PubMed:25825441). Regulates neuronal cell homeostasis by protecting neurons against apoptosis (By similarity). Negatively regulates TLR4-induced interferon beta production by dephosphorylating adapter TICAM2 and inhibiting subsequent TRAM-TRIF interaction (PubMed:25825441). Dephosphorylates also the immunoreceptor tyrosine-based activation motifs/ITAMs of the TCR zeta subunit and thereby negatively regulates TCR-mediated signaling pathway (PubMed:18614237). May act at junctions between the membrane and the cytoskeleton.[UniProtKB/Swiss-Prot Function] |
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Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MG218793 | Ptpn4 (tGFP-tagged) - Mouse protein tyrosine phosphatase non-receptor type 4 (Ptpn4), (10ug) |
CNY 7,890.00 |
|
MR218793 | Ptpn4 (Myc-DDK-tagged) - Mouse protein tyrosine phosphatase, non-receptor type 4 (Ptpn4) |
CNY 6,784.00 |
|
MR218793L3 | Lenti ORF clone of Ptpn4 (Myc-DDK-tagged) - Mouse protein tyrosine phosphatase, non-receptor type 4 (Ptpn4) |
CNY 9,030.00 |
|
MR218793L4 | Lenti ORF clone of Ptpn4 (mGFP-tagged) - Mouse protein tyrosine phosphatase, non-receptor type 4 (Ptpn4) |
CNY 9,030.00 |