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Ctnna1 (NM_009818) Mouse Untagged Clone
CAT＃: MC222501
Ctnna1 (untagged) - Mouse catenin (cadherin associated protein), alpha 1 (Ctnna1), (10ug)
CNY 11,690.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 2010010M04Rik; AA517462; AI988031; Catna1 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC222501 representing NM_009818
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGACTGCCGTCCACGCAGGCAACATAAACTTCAAATGGGACCCCAAAAGTCTGGAGATTAGGACTCTGG CTGTTGAAAGACTGTTGGAGCCTCTTGTTACACAGGTTACAACCCTGGTAAACACCAATAGTAAAGGGCC GTCTAATAAAAAGAGAGGCCGTTCTAAGAAGGCCCATGTTTTGGCTGCATCTGTTGAACAAGCAACTGAG AATTTCTTGGAAAAGGGGGATAAAATTGCAAAAGAGAGCCAGTTTCTCAAGGAGGAGCTTGTGGTTGCTG TAGAAGATGTTCGAAAACAAGGAGATTTGATGAAGAGCGCTGCTGGGGAGTTTGCAGATGATCCATGCTC TTCTGTGAAGCGAGGCAACATGGTCCGGGCAGCTCGAGCTTTGCTCTCTGCCGTCACCCGGCTGCTGATT CTGGCTGACATGGCAGATGTCTACAAATTACTTGTTCAGCTGAAAGTTGTGGAAGATGGTATATTGAAAC TGAGGAATGCTGGCAATGAACAAGACTTAGGGATACAGTACAAAGCTCTGAAACCAGAAGTAGATAAGCT GAACATCATGGCAGCAAAAAGACAACAGGAACTAAAAGATGTGGGCAATCGTGATCAGATGGCTGCAGCT AGAGGAATCCTGCAGAAAAATGTTCCAATCCTCTATACTGCATCCCAGGCATGTCTACAACACCCTGATG TTGCAGCCTATAAGGCCAACCGGGACTTGATATACAAGCAGCTGCAGCAGGCCGTCACAGGAATTTCTAA TGCAGCCCAGGCTACTGCATCAGATGATGCTGCCCAGCACCAGGGTGGCAGTGGCGGAGAGCTGGCATAC GCTCTCAACAACTTTGATAAACAAATCATTGTGGACCCCTTGAGCTTCAGCGAGGAGCGCTTTAGGCCGT CCCTGGAGGAGCGCCTGGAAAGCATTATTAGTGGGGCTGCCCTGATGGCTGACTCATCCTGCACACGTGA TGACCGTCGGGAGCGCATTGTGGCAGAGTGTAATGCTGTCCGCCAGGCTCTACAGGACCTGCTCTCAGAA TACATGGGCAACGCTGGACGTAAAGAAAGAAGTGATGCACTCAACTCTGCAATAGATAAAATGACCAAGA AGACCAGGGACTTGCGTAGACAGCTTCGCAAAGCTGTCATGGACCACGTATCAGATTCTTTCCTGGAGAC CAATGTCCCTCTATTAGTACTGATTGAAGCTGCAAAGAATGGAAATGAGAAAGAAGTTAAGGAATATGCC CAAGTTTTTCGTGAACATGCCAACAAACTGATTGAGGTTGCCAACCTGGCCTGTTCAATCTCCAACAATG AAGAAGGCGTGAAGCTTGTCCGAATGTCTGCAAGCCAGTTAGAAGCGCTGTGTCCTCAGGTTATCAATGC TGCATTGGCGTTGGCAGCAAAGCCGCAGAGTAAACTGGCCCAAGAGAACATGGATCTTTTTAAAGAGCAA TGGGAAAAGCAAGTCCGTGTTCTCACAGATGCTGTTGATGACATTACTTCCATCGATGACTTCTTGGCTG TCTCAGAGAACCACATTTTAGAAGATGTGAACAAGTGTGTTATTGCTCTCCAAGAGAAAGACGTGGATGG GCTGGATCGCACTGCCGGTGCCATCCGAGGCCGGGCAGCCCGAGTCATTCATGTAGTCACCTCAGAGATG GACAACTACGAGCCAGGAGTTTACACAGAGAAGGTTCTGGAAGCCACCAAGCTCCTCTCCAACACAGTCA TGCCGCGCTTCACTGAGCAGGTGGAAGCAGCTGTGGAAGCCCTCAGCTCGGACCCGGCCCAGCCCATGGA TGAGAATGAGTTCATCGACGCCTCCCGTCTGGTGTACGACGGCATCCGGGACATCCGGAAAGCAGTGCTG ATGATCAGGACCCCCGAGGAGTTGGACGACTCTGACTTCGAGACTGAAGACTTTGATGTCAGAAGCAGGA CCAGTGTCCAGACAGAAGATGACCAGCTGATAGCTGGCCAGAGCGCCCGGGCGATCATGGCTCAGCTTCC TCAGGAGCAAAAAGCAAAGATTGCAGAACAGGTGGCCAGTTTCCAGGAAGAGAAGAGCAAGCTGGATGCT GAAGTGTCCAAGTGGGATGACAGTGGCAATGACATCATTGTGCTGGCCAAGCAGATGTGCATGATCATGA TGGAGATGACCGACTTCACCCGAGGCAAAGGTCCACTCAAAAACACCTCTGACGTGATCAGTGCTGCCAA GAAAATTGCGGAGGCGGGATCCAGGATGGACAAGCTCGGCCGGACCATCGCAGACCATTGCCCAGACTCG GCATGCAAGCAGGACCTGCTGGCCTACCTTCAGCGCATCGCTCTCTACTGCCACCAGCTCAACATCTGCA GCAAAGTCAAGGCTGAAGTACAGAACCTTGGTGGAGAGCTGGTCGTCTCTGGGGTGGACAGCGCCATGTC CCTGATCCAGGCGGCCAAGAACTTGATGAATGCTGTTGTGCAGACAGTGAAGGCGTCCTACGTGGCTTCC ACCAAATACCAGAAGTCACAGGGGATGGCTTCCTTGAACCTTCCTGCTGTGTCATGGAAGATGAAGGCCC CTGAGAAGAAGCCGTTGGTGAAGAGAGAGAAGCAGGATGAGACGCAGACCAAGATTAAACGAGCTTCTCA GAAGAAACACGTGAACCCAGTGCAGGCCCTGAGCGAGTTCAAAGCCATGGACAGCATCTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_009818 |
| Insert Size | 2721 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_009818.1, NP_033948.1 |
| RefSeq Size | 3713 bp |
| RefSeq ORF | 2721 bp |
| Locus ID | 12385 |
| UniProt ID | P26231 |
| Gene Summary | Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherens junctions components. The homodimeric form may regulate actin filament assembly and inhibit actin branching by competing with the Arp2/3 complex for binding to actin filaments. May play a crucial role in cell differentiation.[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG211134 | Ctnna1 (tGFP-tagged) - Mouse catenin (cadherin associated protein), alpha 1 (Ctnna1) |
CNY 7,890.00 |
|
| MR211134 | Ctnna1 (Myc-DDK-tagged) - Mouse catenin (cadherin associated protein), alpha 1 (Ctnna1) |
CNY 6,640.00 |
|
| MR211134L3 | Lenti ORF clone of Ctnna1 (Myc-DDK-tagged) - Mouse catenin (cadherin associated protein), alpha 1 (Ctnna1) |
CNY 9,030.00 |
|
| MR211134L4 | Lenti ORF clone of Ctnna1 (mGFP-tagged) - Mouse catenin (cadherin associated protein), alpha 1 (Ctnna1) |
CNY 9,030.00 |
