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Incenp (NM_016692) Mouse Untagged Clone
CAT＃: MC222311
Incenp (untagged) - Mouse inner centromere protein (Incenp), (10ug)
CNY 11,210.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 2700067E22Rik; AU019509; C77457; C130081E20 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC222311 representing NM_016692
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGGGACCACAGCCCCAGGGCCTATTTGCCTTCTGGATCTATGTGACCAGAAACTCCTGGACTTTGTCT GCAATGTGGACAACAAGGACTTCATGTGGCTCAAGGAGATTGAGGAGGAGGCTGAGCGCATGTTTATCAG AGAATTCAGCAATGAGCCAGAGCTGATGCCCAAAACTCCTTCTCAGAAAAACCGTCGGAAGAAGAGGCGG GTGTCTAACATTCAGGATGAAAACAGAGATCCCGTGAGGAAAAGGTTATCCCGCAGAAAGTCTCGGAGCA GTCAGGTGGGTACCCGGCACCTCCGCAGCAAGCCCGTTACTATTGTTGAGGAGAATGGCTTCCCTGTGTT GCAGCGGATAACCCGGGCCACAGCTGCAGCAGCGGCAGCAGCAGCGGCAGCGTCTGTGGCATCAGCTTCT TCCTCTTCCACTGCTGGGTCTCCCACAGTGCTGACCAAGAAAGCAGTGGTGGAGATAAGCACTAGTGAAC GACTGAGTGCAGAACTACAACTCACTAAGCTCAAAGGTAGCCTTCCTCCATCTCCAGTTTCCCAAGGCAC CCTGACATCAGAGGAGGAACTAACACCCAAGAAATCAGAGGCTGGAAAGCTGGACTCTGTCACAGTGAAC TCCCTCAAGGCTACCCCTCAGAGCCCCAAGAACCGAGGGGTTGGGGAAGGACGTTCTGTTTCCAAGCTCA AGATTGCTCGGGCCTCCTGGGGGCTGCAGGACTCTCCTGGCTCTACAGACTCACCATGGCAAGAGCGGGT GCTTTCTCCTATCCTGCTGAATAACATCTTGCCCACAACAGCCAAGAGCCCTCTTGGGAATATTCGGTCA GTGCGGCGAAGCCTGATTTCCCAGGATTCCCAAGTGCCACTAGCCTCGAAGTATAATTTGGTGGCCAAAC AAGAAAATGGCAGTCGCAGATCAAGCAGAAGGATTGCCAAGAAGGCTGGCAAAGAGCCAGAGGCCTCTGC TCGAATCATTTGTCACAGTTACCTGGAGAGGCTCCTGAATGTTGAAGTGCCTCAGAATGTTGGCCTGGAG CAGGAGCCTGTCGAGGTGGCCGAACCTGAGGAGGCAGAAGAGGAGCAAGAGGTCTCCAAGAACAGTGGGT GTCCCTCCAAACCCCGCAGTGCCACCAAGATTGCGATTAGTACGCCCACCTCGAAGCCTGCGGCCGCTGG TCAGACAACAACTGTTGAAGAGCAAGAAGCTGAGCTTGACCAAACAGATGGACACAGAGAACCACCCCAG AGTGTCAGGAGGAAACGCAGTTACAAACAGGCAATAAGTGAACCGGATGAGGAGCAACTGGAAGATGAAG AACTGCAGCCCTGCCAGAATAAGACCCCTTCCCCACCCTGTCCAGCCAACAAGGTGGTACGGCCCCTCCG GACTTTCCTGCACACAGTGCAGAAGAACCAGATGCTCATGACCCCCACACTGGCCTCCCGCAGCAGTGTC ATGAAGTCCTTTATTAAACGCAACACTCCGCTTCGTGTGGACCCTAAGGAGAAGGAGCGCCAGCGCCTAG AGAGCCTGCGACGGAAGGAGGAGGCCGAGCAGCGGCGCAGACAGAAGGTAGAGGAAGACAAGCGGCGGCG ACTGGAGGAGGTGAAGCTGAAGCGTGAAGAGCGCCTCCGCAAGGTGTTGCAGGCCCGTGAGAGGGTGGAA CAGATGAAGGAGGAAAAGAAGAAGCAGATTGAGCAGAAGTTTGCTCAGATTGATGAGAAGACAGAAAAGG CTAAGGAGGAGCGTCTGGCAGAGAAGGCAAAGAAGAAGGCAACTGCCAAGAAGATGGAAGAGGTAGAGGC ACGAAGGAAGCAGGAGGAGGAGGCACGCAGGCTCAGGTGGCTCCAACAGGAGGAAGAGGAGCGGCGGCAT CAAGAAATGCTACAACGGAAGAAGGAGGAAGAACAGGAGCGCCGCAAAGCAGCTGAGGCCAGGCGCCTGG CAGAACAGCGGGAGCAAGAGAGGCGAAGGGAGCAGGAGCGGCGGGAGCAGGAGCGGAGGGAACAGGAGCG GAGGGAACAGGAACGGAAGGAGCAGGAGCGGCGGGAGCAGGAGCAGGAGCGTCTTCGGGCCAAGAGGGAG ATGCAGGAGAGAGAGAAAGCCCTGCGACTCCAAAAGGAACGACTTCAGAAGGAACTGGAGGAGAAGAAGA GGAAGGAAGAGCAACAGCGCCTGGCTGAGCAGCAACTGCAGGAGGAGCAGGCAAAGAAAGCTAAGGAGGT GGCAGCAGCCAGGAAAGTCCTGAACATGACTGTGGATGTGCAGTCTCCTGTTTGTACCTCATATCAAATG ACTCCACAAGGACCCAAATCCATCCCCAAGATCAGCGTAGACGATTATGGGATGGACCTAAATAGTGATG ACTCCACAGATGATGAGTCCCACCCCCGGAAACCCATCCCTTCCTGGGCCAAAGGCACCCAACTCAGCCA GGCCATTGTCCACCAGTACTACCACCCTCCAAACATTCTAGAGCTCTTCGGATCTATTCTCCCACTGGAC TTGGAGGACATCTTTAAGAAGAGGAAGACTCGCTACCACAAGCGCACTAGCTCTGCTGTTTGGAACTCAC CACCCCTGAAAGCCACCATGGTCCCCAGCAGTGGGGACTAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_016692 |
| Insert Size | 2631 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_016692.3, NP_057901.2 |
| RefSeq Size | 3217 bp |
| RefSeq ORF | 2631 bp |
| Locus ID | 16319 |
| UniProt ID | Q9WU62 |
| Gene Summary | Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Acts as a scaffold regulating CPC localization and activity. The C-terminus associates with AURKB or AURKC, the N-terminus associated with BIRC5/survivin and CDCA8/borealin tethers the CPC to the inner centromere, and the microtubule binding activity within the central SAH domain directs AURKB/C toward substrates near microtubules. The flexibility of the SAH domain is proposed to allow AURKB/C to follow substrates on dynamic microtubules while ensuring CPC docking to static chromatin (By similarity). Activates AURKB and AURKC. Controls the kinetochore localization of BUB1.[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG211041 | Incenp (tGFP-tagged) - Mouse inner centromere protein (Incenp) |
CNY 7,890.00 |
|
| MR211041 | Incenp (Myc-DDK-tagged) - Mouse inner centromere protein (Incenp) |
CNY 6,424.00 |
|
| MR211041L3 | Lenti ORF clone of Incenp (Myc-DDK-tagged) - Mouse inner centromere protein (Incenp) |
CNY 9,030.00 |
|
| MR211041L4 | Lenti ORF clone of Incenp (mGFP-tagged) - Mouse inner centromere protein (Incenp) |
CNY 9,030.00 |
