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Epha5 (NM_007937) Mouse Untagged Clone
CAT＃: MC222308
Epha5 (untagged) - Mouse Eph receptor A5 (Epha5), (10ug)
CNY 11,210.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | AI854630; AW125296; bsk; Cek7; Ehk1; Els1; Hek7; Rek7 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC222308 representing NM_007937
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCGGGGCTCCGGGCCCCGCGGTGCGGGACACCGACGGACCCAGGGCAGAGGTGGCGGCGACGACACCC CCCGCGTCCCTGCCTCTCTGGCAGGCTGCTATTCGGCACCTCTAAAGGGCCCCCTCTGGACGTGCCTTCT CTTGTGTGCGGCGCTCCGGACCCTTTTGGCCAGCCCCAGCAACGAAGTGAATTTGTTGGATTCGCGCACT GTCATGGGGGACCTTGGATGGATTGCTTTTCCAAAGAACGGGTGGGAAGAGATTGGTGAAGTTGATGAGA ACTATGCCCCCATCCACACATACCAAGTGTGCAAAGTTATGGAACAGAATCAGAATAATTGGCTGTTGAC CAGTTGGATCTCTAACGAAGGTGCTTCCAGAATCTTTATTGAACTCAAGTTTACTTTAAGGGACTGCAAC AGCCTTCCTGGAGGACTGGGGACTTGTAAGGAGACATTTAACATGTATTATTTTGAATCAGATGATGAGA ATGGGAGAAGTATCAAAGAGAACCAATACATCAAGATTGATACCATCGCTGCAGATGAGAGCTTCACAGA ACTTGATCTTGGTGACCGTGTCATGAAACTGAATACAGAGGTCAGAGATGTCGGACCTCTGAGCAAAAAG GGATTTTATCTTGCTTTCCAAGATGTCGGTGCTTGCATTGCTCTGGTTTCTGTCCGTGTCTACTATAAAA AGTGTCCCTCTGTAGTAAGACACTTGGCTATCTTCCCTGACACTATCACTGGAGCAGATTCATCACAGTT GTTAGAGGTGTCAGGCTCCTGCGTCAACCATTCTGTGACAGATGATCCTCCCAAGATGCATTGCAGTGCT GAAGGGGAGTGGCTGGTTCCCATTGGGAAATGCATGTGCAAGGCTGGATATGAAGAGAAAAATGGTACCT GCCAAGCTCCTTCTCCAGTCACCAATGTGAAAAAGGGGAAGATTGCAAAGAACAGCATTTCTTTGTCTTG GCAAGAGCCAGATCGCCCCAATGGAATTATCCTGGAGTATGAAATCAAGTACTTTGAAAAGGACCAAGAG ACCAGTTACACAATTATCAAGTCTAAAGAGACCAGTATTACAGCCGAGGGCCTGAAACCTGCATCTGTGT ATGTCTTCCAAATTCGAGCACGTACAGCAGCAGGCTACGGCGTCTTCAGTCGAAGATTTGAGTTTGAAAC CACACCAGTGTCAGTTGCAGCATCTAATGATCAAAGCCAGATTCCCATCATTGCAGTGTCAGTGACAGTG GGAGTCATCTTGTTGGCAGTGATGATCGGCTTCCTCCTCAGTGGCAGTTGCTGCGATTGTGGCTGTGGGA GGGCTTCTTCCCTGTGCGCTGTTGCCCATCCAAGCCTAATATGGCGGTGTGGCTACAGCAAAGCAAAGCA GGATCCAGAAGAGGAAAAGATGCACTTTCATAACGGGCACATTAAACTGCCAGGAGTCAGAACCTATATT GATCCGCACACTTATGAAGATCCCAATCAAGCTGTTCATGAATTTGCGAAGGAGATTGAAGCTTCATGCA TCACCATTGAGAGAGTGATCGGAGCAGGTGAATTTGGTGAAGTTTGCAGTGGACGTTTGAAACTACCTGG AAAAAGAGAATTACCTGTGGCTATCAAAACTCTTAAAGTAGGCTATACTGAAAAGCAGCGCAGAGATTTC CTGGGTGAAGCAAGTATTATGGGGCAGTTCGATCATCCAAACATCATCCATCTAGAAGGTGTTGTGACTA AAAGCAAACCTGTGATGATAGTGACAGAGTACATGGAGAACGGCTCCTTAGACACGTTTTTAAAGAAAAA CGATGGGCAGTTCACTGTGATTCAGCTTGTTGGCATGCTGAGAGGCATCGCTGCAGGAATGAAGTACCTT TCTGACATGGGCTACGTGCATAGAGACCTTGCTGCTAGAAACATCTTAATCAACAGTAACCTTGTGTGCA AGGTGTCTGACTTTGGACTTTCCAGGGTACTGGAAGATGATCCTGAGGCAGCCTACACCACAAGGGGAGG CAAAATTCCAATCAGATGGACTGCCCCGGAGGCAATAGCTTTTCGAAAGTTCACCTCTTCCAGTGATGTC TGGAGCTATGGCATTGTAATGTGGGAAGTTGTATCTTATGGAGAGAGACCCTACTGGGAGATGACCAATC AGGATGTGATCAAGGCAGTAGAAGAAGGCTACCGCCTGCCAAGCCCCATGGATTGCCCTGCTGCTCTCTA TCAATTAATGCTGGATTGCTGGCAGAAAGATCGAAACAGCAGGCCCAAGTTTGATGAAATCGTCAACATG CTGGACAAACTGATACGAAACCCAAGTAGTCTGAAGACACTGGTGAATGCGTCGAGCAGAGTGTCTACAT TGTTGGCAGAACATGGTTCTTTGGGGTCTGGGGCCTACAGATCAGTAGGTGAATGGCTGGAAGCAATCAA AATGGGTCGGTACACAGAGATTTTCATGGAAAATGGATACAGTTCAATGGACGCTGTGGCTCAGGTGACC TTGGAGGATTTGAGGCGCCTGGGAGTGACTCTGGTCGGTCACCAGAAGAAGATCATGAGCAGCCTTCAAG AGATGAAGGTGCAGATGGTAAACGGGATGGTGCCAGTGTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_007937 |
| Insert Size | 2631 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_007937.3, NP_031963.2 |
| RefSeq Size | 7789 bp |
| RefSeq ORF | 2631 bp |
| Locus ID | 13839 |
| UniProt ID | Q60629 |
| Gene Summary | Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Among GPI-anchored ephrin-A ligands, EFNA5 most probably constitutes the cognate/functional ligand for EPHA5. Functions as an axon guidance molecule during development and may be involved in the development of the retinotectal, entorhino-hippocampal and hippocamposeptal pathways. Together with EFNA5 plays also a role in synaptic plasticity in adult brain through regulation of synaptogenesis. In addition to its function in the nervous system, the interaction of EPHA5 with EFNA5 mediates communication between pancreatic islet cells to regulate glucose-stimulated insulin secretion.[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG226341 | Epha5 (tGFP-tagged) - Mouse Eph receptor A5 (Epha5), (10ug) |
CNY 8,016.00 |
|
| MR226341 | Epha5 (Myc-DDK-tagged) - Mouse Eph receptor A5 (Epha5) |
CNY 6,416.00 |
|
| MR226341L3 | Lenti ORF clone of Epha5 (Myc-DDK-tagged) - Mouse Eph receptor A5 (Epha5) |
CNY 9,600.00 |
|
| MR226341L4 | Lenti ORF clone of Epha5 (mGFP-tagged) - Mouse Eph receptor A5 (Epha5) |
CNY 9,600.00 |
