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Kmt5b (NM_144871) Mouse Untagged Clone
CAT＃: MC222189
Suv420h1 (untagged) - Mouse suppressor of variegation 4-20 homolog 1 (Drosophila) (Suv420h1), transcript variant 3, (10ug)
CNY 10,930.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | AA117471; C630029K18Rik; Suv4-20h1; Suv420h1 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC222189 representing NM_144871
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGAAGTGGTTGGGAGACTCCAAGAACATGGTGGTGAATGGCAGGAGAAATGGAGGCAAGTTGTCTAATG ACCATCAGCAGAATCAATCAAAATTACAGCAGCACTCGGGCAAGGACACCCTGAAGACCGGCAGAAACGC CGTTGAGAGGCGGTCCAGCAGATGTCATGGTAACTCGGGATTTGAAGGGCAGAGCCGCTATGTGCCGTCC TCTGGAATGTCCGCCAAGGAGCTCTGTGAGAACGATGACTTAGCAACCAGTTTGGTTCTTGATCCCTACT TAGGTTTTCAGACACACAAAATGAACACTAGATTTCGGCCTATAAAAGGAAGGCAAGAAGAGCTAAAGGA AGTAATTGAACGCTTTAAGAAAGATGAACACTTAGAGAAAGCTTTCAAATGTTTGACTTCTGGGGAATGG GCACGGCATTATTTTCTCAACAAAAACAAAATGCAGGAGAAATTATTCAAGGAACATGTCTTTATTTACT TGCGGATGTTTGCAACTGACAGTGGATTTGAAATACTGCCTTGTAATAGATATTCTTCAGAACAAAATGG AGCCAAGATAGTTGCAACAAAAGAGTGGAAACGAAATGACAAAATAGAATTACTGGTGGGTTGTATTGCC GAACTTTCAGAAATTGAGGAGAACATGCTACTTAGACACGGAGAAAACGACTTCAGTGTCATGTATTCCA CAAGGAAAAATTGTGCTCAACTCTGGCTCGGTCCTGCTGCATTTATAAATCATGATTGCAGACCTAACTG TAAGTTTGTGTCAACTGGTCGAGATACAGCATGCGTTAAGGCTCTGAGAGATATTGAACCTGGAGAAGAA ATTTCTTGTTACTATGGAGATGGCTTTTTTGGAGAAAATAATGAGTTCTGCGAATGTTATACTTGTGAAA GACGGGGAACTGGTGCTTTTAAATCACGAGTAGGACTGCCTGCGCCTGCTCCTGTTATCAATAGCAAATA CGGACTTAGAGAAACAGATAAACGCTTAAATAGGCTTAAAAAGTTAGGTGACAGCAGCAAAAACTCAGAC AGTCAGTCTGTCAGCTCTAACACAGATGCAGACACCACTCAGGAAAAAGACAATGCAACTTCTAATCGAA AATCTTCAGTTGGTGTGAAAAAGAGCAGCAAGAGTCGAGCTCTGACAAGGCCGTCCATGCCGAGAGTCCC GGCTGCTTCCAACTCTACCTCACCCAAGCTAGTGCACACCAACAATCCCCGGGTACCAAAGAAACTGAGA AAGCCGGCAAAGCCTTTACTCTCCAAGATCAGACTGCGGAATCACTGCAAGCGGCTGGACCAGAAGAGCG CATCCCGCAAGCTCGAGATGGGGAGCTTAGTGCTTAAGGAGCCCAAAGTCGTGCTATATAAAAATTTGCC AATTAAGAAAGAAAGGGAGCCAGAGGGACCAGCCCATGCTGCAGTGGGGAGTGGGTGCTTGACTAGACAT GCTGCGAGAGAACACAGGCAGAATCATGGGAGAGGTGCTCATTCGCAGGGCGACAGTTTGCCCTGCACCT ACACAACCCGGCGCTCTTTGAGGACAAGGACAGGTCTGAAGGAGACCACTGACATCAAGCTTGAACCAAG TCCCTTGGATGGCTATAAAAATGGTATACTGGAACCTTGCCCAGACAGTGGCCAGCAGCCAACCCCAGAG GTGCTGGAAGAACTGGCTCCTGAGACTGCACACAGGGAGGAAGCATCCCAGGAGTGTCCCAAGAACGACT CCTGCCTGTCACGAAAGAAATTTCGACAAGTGAAACCTGTGAAACACTTAGCAAAGACCGAGGACTGCAG TCCAGAGCACAGCTTCCCTGGGAAAGACGGGCTGCCAGATTTGCCAGGGTCTCATCCTGATCAAGGTGAG CCCAGTGGCACAGTCAGGGTGCCCGTGAGCCACACGGACTCTGCTCCCTCACCGGTTGGCTGCTCTGTTG TCGCACCCGACAGCTTCACAAAAGACAGCTTCAGAACTGCACAAAGTAAAAAGAAGCGGCGGGTCACCAG GTACGATGCACAGCTGATCCTGGAGAACAGCTCTGGAATCCCCAAGCTGACGCTTCGCAGGCGGCACGAC AGCAGCAGCAAGACAAACGACCATGAGAGTGACGGCGTGAACTCCTCCAAGATCAGCATCAAACTCAGCA AGGACCACGACAGTGACAGCAACCTCTATGTTGCCAAGCTCAGTAACGGGGTCAGCGCAGGGCCGGGCAG CAGCTCCACCAAGCTCAAGATCCAGCTCAAGCGGGATGAGGAGAGCAGGGGGCCATGTGCAGAGGGCCTG CACGAGAACGGGGTGTGCTGCAGCGACCCCCTCTCCCTGCTCGAGTCCCAGATGGAGGTGGACGACTACA GTCAATATGAGGAGGACAGCACAGATGAATCCTCATCTTCTGAGGGGGAGGAGGAGGAGGAGGACTGCGA GGATGACTTCGATGATGACTTCATTCCTCTTCCTCCGGCAAAGCGGCTGAGGCTAATTGTTGGTAAAGAC TCCATAGATATTGACATTTCTTCAAGGAGAAGAGAAGATCAGTCTCTAAGACTGAACGCATGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_144871 |
| Insert Size | 2583 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_144871.4, NP_659120.3 |
| RefSeq Size | 6062 bp |
| RefSeq ORF | 2583 bp |
| Locus ID | 225888 |
| UniProt ID | Q3U8K7 |
| Gene Summary | Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. KMT5B is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2). Plays a role in myogenesis by regulating the expression of target genes, such as EID3.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (3) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a. Variants 3 and 4 both encode isoform b. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG217766 | Suv420h1 (tGFP-tagged) - Mouse suppressor of variegation 4-20 homolog 1 (Drosophila) (Suv420h1) transcript variant 3, (10ug) |
CNY 9,410.00 |
|
| MR217766 | Suv420h1 (Myc-DDK-tagged) - Mouse suppressor of variegation 4-20 homolog 1 (Drosophila) (Suv420h1), transcript variant 3 |
CNY 8,550.00 |
|
| MR217766L3 | Lenti ORF clone of Suv420h1 (Myc-DDK-tagged) - Mouse suppressor of variegation 4-20 homolog 1 (Drosophila) (Suv420h1), transcript variant 3 |
CNY 10,450.00 |
|
| MR217766L4 | Lenti ORF clone of Suv420h1 (mGFP-tagged) - Mouse suppressor of variegation 4-20 homolog 1 (Drosophila) (Suv420h1), transcript variant 3 |
CNY 10,450.00 |
