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Mark1 (NM_145515) Mouse Untagged Clone
CAT＃: MC221734
Mark1 (untagged) - Mouse MAP/microtubule affinity-regulating kinase 1 (Mark1), (10ug)
CNY 10,260.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | AW491150; B930025N23Rik; Emk3; mKIAA1477; mPar-1c; Par-1c |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC221734 representing NM_145515
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGTCGGCGCGGACGCCATTGCCCACGGTGAACGAGCGGGACACGGAGAACCATACGTCTGTGGATGGCT ACACTGAAACACATATCCCGCCTGCCAAGTCAAGTAGCAGACAGAACCTTCCCCGGTGTAGAAACTCCAT TACGTCAGCGACAGATGAACAGCCTCACATCGGAAATTACCGCTTACAGAAAACAATAGGGAAAGGAAAT TTTGCCAAAGTGAAATTGGCAAGACATGTTCTAACAGGTAGAGAGGTCGCTGTGAAAATAATAGACAAAA CTCAGCTAAACCCTACCAGTCTACAGAAGTTGTTCCGAGAAGTACGAATAATGAAGATACTGAACCATCC TAACATAGTGAAACTGTTTGAAGTTATTGAAACAGAGAAGACACTCTATTTGGTCATGGAATACGCAAGT GGGGGTGAAGTCTTTGATTACTTAGTTGCCCACGGAAGAATGAAAGAGAAAGAGGCCCGTGCCAAATTCA GGCAGATTGTATCTGCTGTACAGTATTGCCATCAAAAATGCATTGTTCACCGTGATCTTAAGGCTGAAAA CCTTCTCCTTGATGCTGATATGAATATTAAAATTGCTGACTTTGGTTTTAGCAATGAATTCACAGTGGGG AACAAATTGGACACATTCTGTGGAAGCCCGCCTTATGCTGCCCCCGAGCTTTTCCAAGGCAAGAAGTACG ATGGGCCAGAAGTGGATGTGTGGAGTCTGGGCGTCATTCTCTACACGCTGGTCAGTGGCTCGCTGCCGTT TGATGGCCAGAATCTAAAGGAACTTCGGGAGCGAGTCCTTCGAGGGAAGTACCGCATCCCCTTCTACATG TCCACAGACTGTGAGAATCTCCTGAAGAAACTGTTAGTGCTGAATCCCATAAAGCGGGGCAGCCTGGAGC AAATAATGAAAGACCGATGGATGAATGTTGGTCATGAGGAAGAAGAGCTAAAGCCGTACTCTGAGCCTGA GCTTGATCTCAGCGATGCAAAAAGAATAGACATTATGGTCACCATGGGTTTTGCACGAGATGAAATCAAT GATGCCTTAGTAAGTCAGAAATATGATGAAGTTATGGCTACTTACATCCTTCTAGGTAGAAAACCACCCG AGTTCGAAGGTGGTGAGTCACTGTCCAGTGGGAGCTTGTGCCAGCGGTCGCGGCCGAGCAGCGACCTGAA CAACAGCACCCTTCAGTCGCCTGCTCACCTGAAGGTCCAGCGGAGCATCTCGGCCAACCAGAAGCAGAGG CGCTTCAGCGACCACGCCGGCCCCTCCATCCCCCCTGCCGTCTCATACACCAAGAGGCCTCAGGCCAACA GCGTGGAGAGTGAACAGAAGGAGGAGTGGGGCAAAGACACAGCCCGCAGACTTGGCAGCACCACAGTGGG ATCAAAGAGCGAAGTCACAGCCAGCCCCTTGGTGGGGCCAGACAGGAAAAAGTCCACAGCGAGCCCAAGT AACAACGTATATTCTGGCGGTAGCATGGCGAGGAGGAATACGTATGTGTGTGAGAGGAGCACAGACCGGT ACGCAGCCTTGCAGAATGGAAGAGACAGCAGCCTTACAGAGATGTCTGCCAGCAGCATGTCCTCGGCGGG CTCCACCGTGGCCTCTGCTGGCCCCTCAGCACGTCCCCGCCACCAGAAATCTATGTCAACCTCTGGCCAC CCTATAAAAGTTACACTGCCAACCATTAAAGATGGCTCAGAAGCGTATCGGCCTGGTGCAGCTCAGAGAG TGCCTGCTGCTTCTCCGTCTGCTCACAGCATCAGTGCCAGCACTCCAGACAGGACCCGCTTCCCCCGAGG GAGCTCCAGCCGAAGCACTTTCCATGGGGAACAGCTCCGAGAGCGGCGCAGCGCGGCTTACAACGGACCA CCGGCCTCCCCATCCCACGAAACGGGTGCGTTTGCACATGCCAGAAGGGGCACGTCAACCGGCATCATCA GCAAAATCACCTCCAAGTTCGTCCGCAGGGATCCAAGTGAAGGCGAAGCCAGCGGCAGAGCCGACACAGC CAGAGGTTCATCGGGAGATCCCAAAGAGAGAGACAAGGACGAGGGCAAAGAGGCCAAGCCCCGCTCCCTG CGCTTCACCTGGAGCATGAAGACCACGAGCTCCATGGACCCCAACGACATGCTGAGGGAGATCCGCAAGG TGCTGGATGCCAACACCTGTGACTATGAGCAGAAAGAGAGGTTCCTGCTCTTCTGCGTTCACGGAGACGC TCGGCAGGACAGCCTCGTACAGTGGGAGATGGAGGTCTGCAAGTTGCCTCGGCTCTCACTCAACGGGGTC CGCTTCAAGCGAATATCTGGGACATCTATTGCCTTTAAGAACATTGCATCCAAAATAGCAAATGAGCTTA AGCTGTAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_145515 |
| Insert Size | 2388 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_145515.2, NP_663490.2 |
| RefSeq Size | 4565 bp |
| RefSeq ORF | 2388 bp |
| Locus ID | 226778 |
| UniProt ID | Q8VHJ5 |
| Gene Summary | Serine/threonine-protein kinase (By similarity). Involved in cell polarity and microtubule dynamics regulation. Phosphorylates DCX, MAP2 and MAP4. Phosphorylates the microtubule-associated protein MAPT/TAU (By similarity). Involved in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. Involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity and microtubule dynamics, possibly by phosphorylating and regulating DCX. Also acts as a positive regulator of the Wnt signaling pathway, probably by mediating phosphorylation of dishevelled proteins (DVL1, DVL2 and/or DVL3).[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG215783 | Mark1 (tGFP-tagged) - Mouse MAP/microtubule affinity-regulating kinase 1 (Mark1), (10ug) |
CNY 7,700.00 |
|
| MR215783 | Mark1 (Myc-DDK-tagged) - Mouse MAP/microtubule affinity-regulating kinase 1 (Mark1) |
CNY 5,824.00 |
|
| MR215783L3 | Lenti ORF clone of Mark1 (Myc-DDK-tagged) - Mouse MAP/microtubule affinity-regulating kinase 1 (Mark1) |
CNY 8,930.00 |
|
| MR215783L4 | Lenti ORF clone of Mark1 (mGFP-tagged) - Mouse MAP/microtubule affinity-regulating kinase 1 (Mark1) |
CNY 8,930.00 |
