United States
Germany
Japan
United Kingdom
China
Rasgrp1 (NM_011246) Mouse Untagged Clone
CAT＃: MC221698
Rasgrp1 (untagged) - Mouse RAS guanyl releasing protein 1 (Rasgrp1), (10ug)
CNY 10,260.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | Rasgrp |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC221698 representing NM_011246
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGGAACCCTGGGCAAGGCGAGAGAGGCTCCGCGGAAACCTTGCCATGGCTCCAGAGCTGGCCCCAAAG CAAGACTAGAGGCCAAATCAACCAACAGCCCTCTCCCTGCCCAGCCCAGCTTGGCCCAGATCACCCAGTT CCGAATGATGGTGTCCCTGGGACATTTGGCCAAAGGAGCCAGCCTGGATGATCTTATTGACAGCTGCATT CAATCTTTTGATGCGGATGGAAACCTGTGTCGGAATAACCAACTGTTACAAGTCATGCTAACCATGCACC GGATCATCATCTCCTCAGCCGAGCTGCTACAAAAAGTCATGAATCTATATAAGGATGCCCTGGAAAAGAA TTCTCCAGGAGTTTGCCTGAAGATCTGCTATTTTGTCAGGTATTGGATAACAGAATTCTGGATCATGTTC AAGATGGATGCCAGCTTGACCAGCACCATGGAAGAGTTCCAAGACCTGGTGAAAGCCAATGGTGAGGAGA CCCACTGCCACCTCATCGACACGACCCAAATTAATTCTCGAGACTGGTCCAGGAAACTGACTCAGAGGAT AAAATCGAATACTAGCAAGAAGCGCAAAGTGTCCCTGCTGTTTGACCATCTGGAACCTGAAGAACTGTCT GAACACCTCACCTACCTTGAGTTCAAGTCCTTCCGACGGATATCTTTCTCTGATTACCAAAATTACCTTG TAAATAGCTGCGTAAAAGAGAACCCCACCATGGAGAGGTCCATTGCCCTGTGCAATGGCATCTCCCAGTG GGTACAACTGATGGTTCTCAGCCGTCCCACCCCGCAGCTCCGGGCAGAGGTCTTCATCAAGTTCATCCAT GTGGCTCAGAAACTCCACCAGCTACAGAACTTCAACACGCTGATGGCTGTGATCGGGGGACTGTGTCACA GCTCCATCTCCAGGCTTAAGGAAACAAGTTCACATGTCCCACATGAGATCAATAAGGTTCTGGGCGAGAT GACTGAACTGCTGTCCTCCTGCAGAAACTATGACAACTACAGGCGAGCCTATGGGGAGTGCACCCACTTC AAAATCCCCATACTGGGTGTGCACCTCAAGGACCTCATATCCCTGTATGAGGCTATGCCCGACTATCTGG AAGATGGGAAGGTGAATGTCCAAAAGCTCCTGGCCCTTTACAATCATATCAATGAATTGGTCCAGCTGCA GGAGATGGCCCCACCATTGGATGCCAACAAGGACTTGGTGCATCTGCTGACGTTATCCCTGGATCTATAC TATACAGAAGATGAAATCTATGAGCTTTCCTATGCCCGGGAGCCGAGGAACCACAGAGCTCCGCCACTGA CACCTTCGAAGCCACCAGTTGTAGTAGACTGGGCCTCTGGAGTGTCTCCCAAACCTGACCCAAAGACCAT CAGCAAACACGTCCAAAGGATGGTGGATTCTGTCTTTAAGAACTATGATCTCGACCAGGATGGCTATATC TCTCAGGAGGAGTTTGAGAAGATCGCTGCAAGCTTTCCATTTTCCTTCTGTGTGATGGACAAAGATAGGG AAGGCCTCATCAGCAGAGACGAGATCACGGCCTACTTCATGAGGGCCAGCTCCATCTATTCCAAGCTGGG CCTGGGCTTTCCACACAACTTTCAAGAAACCACTTACCTGAAGCCCACCTTCTGTGACAACTGTGCTGGC TTTCTCTGGGGCGTGATCAAGCAAGGCTATCGCTGTAAAGACTGCGGGATGAACTGCCACAAACAGTGCA AAGACCTGGTGGTGTTCGAGTGCAAGAAGCGAATCAAGAGCCCAGCAATATCCACAGAGAACATCAGCTC TGTGGTACCAATGTCCACCCTTTGTCCACTGGGAACCAAAGATCTGCTCCATGCACCCGAAGAAGGATCT TTCATTTTCCAAAACGGAGAGATTGTGGACCACAGTGAGGAGAGCAAGGATAGGACCATCATGCTCCTCG GAGTGTCCTCCCAGAAAATTTCAGTTCGGCTGAAGAGGACTGTTGCCCACAAGAGCACCCAAACAGAATC GTTCCCGTGGGTTGGTGGCGAGACGACCCCTGGTCACTTTGTGCTGTCTTCTCCAAGGAAGTCGGCGCAG GGCGCTCTTTATGTGCACAGTCCAGCATCTCCATGCCCCAGCCCAGCACTGGTCCGAAAGCGGGCATTCG TCAAGTGGGAGAACAAAGAGTCCCTTATAAAACCAAAACCAGAACTTCACCTCCGGCTCCGGACCTACCA AGAACTGGAACAGGAAATAAATACCCTGAAAGCAGATAACGATGCTCTGAAGATCCAACTGAAGTACGCA CAGAAGAAAATAGAATCCCTGCAGCTTGGGAAAAGCAATCATGTCTTAGCCCAGATGGACCACGGTGATA GTGCTTAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_011246 |
| Insert Size | 2388 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_011246.2, NP_035376.1 |
| RefSeq Size | 5155 bp |
| RefSeq ORF | 2388 bp |
| Locus ID | 19419 |
| UniProt ID | Q9Z1S3 |
| Gene Summary | Functions as a calcium- and diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of bound GDP for GTP. Activates the Erk/MAP kinase cascade. Regulates T-cell/B-cell development, homeostasis and differentiation by coupling T-lymphocyte/B-lymphocyte antigen receptors to Ras. Regulates NK cell cytotoxicity and ITAM-dependent cytokine production by activation of Ras-mediated ERK and JNK pathways (By similarity). Functions in mast cell degranulation and cytokine secretion, regulating FcERI-evoked allergic responses (PubMed:17190838). May also function in differentiation of other cell types. Proto-oncogene, which promotes T-cell lymphomagenesis when its expression is deregulated (PubMed:15829980, PubMed:17210708).[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG210704 | Rasgrp1 (tGFP-tagged) - Mouse RAS guanyl releasing protein 1 (Rasgrp1) |
CNY 6,370.00 |
|
| MR210704 | Rasgrp1 (Myc-DDK-tagged) - Mouse RAS guanyl releasing protein 1 (Rasgrp1) |
CNY 5,824.00 |
|
| MR210704L3 | Lenti ORF clone of Rasgrp1 (Myc-DDK-tagged) - Mouse RAS guanyl releasing protein 1 (Rasgrp1) |
CNY 7,700.00 |
|
| MR210704L4 | Lenti ORF clone of Rasgrp1 (mGFP-tagged) - Mouse RAS guanyl releasing protein 1 (Rasgrp1) |
CNY 7,700.00 |
其它Rasgrp1产品
