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Abcg8 (NM_026180) Mouse Untagged Clone
CAT＃: MC220347
Abcg8 (untagged) - Mouse ATP-binding cassette, sub-family G (WHITE), member 8 (Abcg8), (10ug)
CNY 8,650.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 1300003C16Rik; AI114946; sterolin-2 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC220347 representing NM_026180
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCTGAGAAAACCAAAGAAGAGACCCAGCTGTGGAATGGGACTGTACTTCAGGATGCTTCGCAGGGCC TCCAGGACAGCTTGTTCTCCTCGGAAAGTGACAACAGTCTGTACTTCACCTACAGTGGTCAGTCCAACAC TCTGGAGGTCAGAGATCTCACCTACCAGGTGGACATCGCCTCTCAGGTGCCTTGGTTTGAGCAGCTGGCT CAGTTCAAGATACCCTGGAGGTCTCATAGCAGCCAAGACTCCTGTGAGCTGGGCATCCGAAATCTAAGCT TCAAAGTGAGGAGTGGACAGATGCTGGCCATCATAGGGAGCTCAGGCTGCGGGAGAGCCTCACTACTCGA CGTGATCACAGGCAGAGGCCACGGTGGCAAGATGAAATCAGGACAAATTTGGATAAATGGGCAACCCAGT ACGCCTCAGCTGGTGAGGAAGTGCGTTGCGCATGTGCGGCAGCATGACCAACTGCTGCCCAACCTGACCG TCAGAGAGACCCTGGCTTTCATTGCCCAGATGCGCCTGCCCAGGACCTTCTCCCAGGCCCAGCGTGACAA ACGGGTGGAAGACGTAATCGCCGAGCTGCGGCTGCGGCAGTGCGCCAACACCAGAGTGGGCAACACGTAT GTACGTGGGGTGTCCGGGGGTGAGCGCCGACGAGTGAGCATTGGGGTGCAGCTCCTGTGGAACCCAGGAA TCCTCATTCTGGATGAACCCACTTCTGGCCTCGACAGCTTCACAGCCCACAATCTGGTGACAACCTTGTC CCGCCTGGCCAAGGGCAACAGGCTGGTGCTCATCTCCCTCCACCAGCCTCGCTCTGACATCTTCAGGCTA TTTGACCTGGTCCTTCTGATGACATCTGGCACCCCTATCTACCTGGGGGCGGCGCAGCAAATGGTGCAGT ACTTCACATCCATTGGCCACCCTTGTCCTCGCTATAGCAACCCTGCGGACTTCTACGTGGACTTGACCAG CATCGACAGACGCAGCAAAGAACGGGAGGTGGCCACCGTGGAGAAGGCACAGTCTCTTGCAGCCCTGTTC CTAGAAAAAGTACAAGGCTTTGATGACTTTCTGTGGAAAGCTGAGGCAAAGGAACTCAACACAAGCACCC ACACAGTCAGCCTGACCCTCACACAGGACACTGACTGTGGGACTGCTGTTGAGCTGCCCGGGATGATAGA GCAGTTTTCCACCCTGATCCGTCGTCAGATTTCCAATGACTTCCGGGACCTGCCCACGCTGCTCATTCAT GGGTCGGAAGCCTGCCTGATGTCCCTCATCATTGGCTTCCTTTACTACGGCCATGGGGCCAAGCAGCTCT CCTTCATGGACACAGCAGCCCTCCTCTTCATGATAGGGGCGCTCATTCCTTTCAATGTCATCCTGGATGT CGTCTCCAAATGTCACTCGGAGAGGTCAATGCTGTACTATGAGCTGGAAGACGGGCTGTACACTGCTGGT CCTTATTTCTTTGCCAAGATCCTAGGAGAATTGCCGGAGCACTGTGCCTACGTCATCATCTACGCGATGC CCATCTACTGGCTGACAAACCTGCGGCCCGTGCCTGAGCTCTTCCTTCTACACTTCCTGCTCGTGTGGTT GGTGGTCTTCTGCTGCAGGACCATGGCCCTGGCTGCCTCTGCCATGCTGCCCACCTTCCACATGTCCTCC TTCTTCTGCAATGCCCTCTACAACTCCTTCTACCTTACTGCCGGCTTCATGATAAACTTGGACAACCTGT GGATAGTGCCTGCATGGATCTCCAAGCTGTCGTTCCTCCGGTGGTGCTTCTCGGGGCTGATGCAGATTCA ATTTAATGGACACCTTTACACCACACAAATCGGCAACTTCACCTTCTCCATCCTCGGAGACACGATGATC AGTGCCATGGACCTGAACTCGCATCCACTCTATGCGATCTACCTCATTGTCATCGGCATCAGCTACGGCT TCCTGTTCCTGTACTATCTATCCTTGAAGCTCATCAAACAGAAGTCAATTCAAGACTGGTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_026180 |
| Insert Size | 2022 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_026180.3, NP_080456.1 |
| RefSeq Size | 3684 bp |
| RefSeq ORF | 2022 bp |
| Locus ID | 67470 |
| UniProt ID | Q9DBM0 |
| Gene Summary | ABCG5 and ABCG8 form an obligate heterodimer that mediates Mg(2+)- and ATP-dependent sterol transport across the cell membrane (PubMed:16352607, PubMed:16867993, PubMed:18402465). Plays an essential role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile (PubMed:12444248, PubMed:14504269, PubMed:14657202, PubMed:25378657). Plays an important role in preventing the accumulation of dietary plant sterols in the body (PubMed:12444248, PubMed:14657202). Required for normal sterol homeostasis (PubMed:12444248, PubMed:14657202). The heterodimer with ABCG5 has ATPase activity (PubMed:16352607, PubMed:16867993).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG227387 | Abcg8 (tGFP-tagged) - Mouse ATP-binding cassette sub-family G (WHITE) member 8 (Abcg8), (10ug) |
CNY 7,410.00 |
|
| MR227387 | Abcg8 (Myc-DDK-tagged) - Mouse ATP-binding cassette, sub-family G (WHITE), member 8 (Abcg8) |
CNY 7,392.00 |
|
| MR227387L3 | Lenti ORF clone of Abcg8 (Myc-DDK-tagged) - Mouse ATP-binding cassette, sub-family G (WHITE), member 8 (Abcg8) |
CNY 8,650.00 |
|
| MR227387L4 | Lenti ORF clone of Abcg8 (mGFP-tagged) - Mouse ATP-binding cassette, sub-family G (WHITE), member 8 (Abcg8) |
CNY 8,650.00 |
