5730559C18Rik (NM_028872) Mouse Untagged Clone
CAT#: MC220258
5730559C18Rik (untagged) - Mouse RIKEN cDNA 5730559C18 gene (5730559C18Rik), (10ug)
CNY 8,550.00
Product images
![](https://cdn.origene.com/img/defaults-img.jpg)
Specifications
Product Data | |
Type | Mouse Untagged Clone |
Tag | Tag Free |
Synonyms | 1700034M08Rik; 4933426C09Rik; AI586180; D1Mgi54 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>MC220258 representing NM_028872
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCCCCAGGGGACAGATGTCTTGGGATCTTTAACATTTGGGATGCTGCAAATGCCGAAGTTAAATGAAA TACCTCCGGGGAGGGGAGGCCCGGGGGAGCCTTGGGGAGAGGGAAGATGGGCGGGACCAACAGGTCCTGA AGCTGCGCGACCGGCGCGGGGGGCGCGGGGGCAGGCGCGAGGCGCCAGAGCTCGGTGGGACAGCTGGGAA CACTCCAGACTACCTACACATCCTGGCCCAGGCTGGGACCAGTGCAGCCCCTCCTTCCTCTGTGCCCCCT CTTCCCAGAAACTCATCATGGAGAGTAAGGATGAAGTCAGTGACTCCGACAGCGGCATCATCCTGCAGTC TGGCCCGGACAGCCCTGTCTCTCCAATGAAAGAGCTGACCAATGCAGTACGCAAGCAGCAGAGGGCTCTG GAAGCGAGGCTGGAGGCCTGCCTGGAGGAGCTGCGCAGACTCTGCCTGAGGGAGGCGGAGCTGACTGGGA CTTTGCCGGCAGAGTATCCCCTTAAGCCTGGTGAGAAGGCCCCCAAGGTCCGGCGCAGGATCGGAGCAGC GTACAAGCTGGATGAGTGGGCCCTCCACAGAGAGGACCCCCTGAGCAGCCTAGAGCGCCAGTTGGCTCTG CAGCTTCAGATCACCGAGGCGGCTCGAAGGCTGTGTGCAGAGGAGAACCTCAGCAGACAGGCACGCAGGC AGCGGAAGCACGCTGCGCTGCAGGAGGAGAAGAAGCTGCGGGACCTTCAGCGTTGCCTGGGTGATCGGCG GCGGAACAGTGAGCCCCCTCCTACCACTGTGCCCTCCCTGGGCAGAGAACTCAGTGCCTCTGACGACAGC TCCCTGTCTGATGGGCTGCTCCTGGAGGAAGAAGACTCCCAAGCGCCAAAACCTCCCCCAGAGTCACCGG CACCACCTTCGCGGCCTCTCCCACCCCAGAGCCTTGAGGGCCTACAGCCAACAGGACCTGAGTCTGGCGG CCAGGAACGGGCTCCCATCCAAAACAGTCCCTGGAAGGAGACCAGCCTGGACCACCCCTATGAGAAGCCC AGGAAGTCTTCTGAGCTCAGTAGCGAGTCCAGCAGCCCGGCCACCACTCCTCAGGACCAGCCCAACCCTT CCAGCCTGTGGGTGCTGGATGCTGCCTCTTACCACGTGGTCCCCATCCGAAATGTTCCCGGCCAGCGTCA GGGCCGCACCAGTGCCCCAGCCACCCCTGAGATGCAGGGCAGGAGGGGCCAGTCACAGTCTCTGAGGGTG GACTCCTTCCGAGCAGGCGCGGAGGGCCGAGGTCGCAGTGCCTTTCCCCGCCGCCGCCCCACTCATTACA CAGTGACAGTGCCAGACTCCTGCTTCACACCCGGCAAGCCCCCACTGCCACACCCTGCCTGCCATTCCTG CTCTGAAGACAGTGGCTCTGATGTCTCCAGCATCTCCCATCCCACCTCACCTGGCAGCAGCAGTCCAGAC ATCTCCTTTCTGAGGCCCCTCTGTCTCCCTGAGCCACCTCGCCACCGTGGGGCCTGGGGCCCAGCCTGTG GCAGAGAGCTGGCCCCTCATTACTCTAAACTTCTGCTACCCGCTGGATACTTCCCAACGGGGCGCTATGT GATGGTGGCCGAGGGCCACCTGCCGCCGGGCGAGTGGGAGCTGTGTCGTGCAGCCGTGGGTGCTGCCTAT GACGAGGAAGGTGCACCCCTGCGTTACCAGCGACTGGTACCCTCCCACAGCCGCATTGTGCGCACACCCT CACTAAAGGACAGTCCTGCGGGCCGGGGACTCAGCAAGGCAGCAGTCTCGGAGGAGCTCAAGTGGTGGCA TGAACGCGCACGTCTCCGGAGCAGCCGCCCCCACTCGCTCGACCGCCAAGGGGCGTTCCGTGTTAGGAGT CTGCCTCCTGGGAGGGAGAGCTTCGGGCGGGCCTCAGGACCCAGGACACAGGTGCCCCCCGTGTACGTAC TCCGGAGGTCGACGGACGGGGCCCCAGTGCAAGTCTTTGTGCCTGAGAACGGAGAGATTATCAGCCAAGT GTAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
Restriction Sites | SgfI-MluI |
ACCN | NM_028872 |
Insert Size | 2034 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_028872.3, NP_083148.3 |
RefSeq Size | 3013 bp |
RefSeq ORF | 2034 bp |
Locus ID | 67313 |
UniProt ID | Q7TN12 |
Gene Summary | Expressed in peripheral macrophages and intestinal myeloid-derived cells, is required for optimal PRR (pattern recognition receptor)-induced signaling, cytokine secretion, and bacterial clearance. Upon stimulation of a broad range of PRRs (pattern recognition receptor) such as NOD2 or TLR2, TLR3, TLR4, TLR5, TLR7 and TLR9, associates with YWHAQ/14-3-3T, which in turn leads to the recruitment and activation of MAP kinases and NF-kappa-B signaling complexes that amplifies PRR-induced downstream signals and cytokine secretion (By similarity). In the intestine, regulates adherens junction stability by regulating the degradation of CYTH1 and CYTH2, probably acting as substrate cofactor for SCF E3 ubiquitin-protein ligase complexes. Stabilizes adherens junctions by limiting CYTH1-dependent ARF6 activation (PubMed:29420262).[UniProtKB/Swiss-Prot Function] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MG209867 | 5730559C18Rik (tGFP-tagged) - Mouse RIKEN cDNA 5730559C18 gene (5730559C18Rik) |
CNY 6,370.00 |
|
MR209867 | 5730559C18Rik (Myc-DDK-tagged) - Mouse RIKEN cDNA 5730559C18 gene (5730559C18Rik) |
CNY 4,944.00 |
|
MR209867L3 | Lenti ORF clone of 5730559C18Rik (Myc-DDK-tagged) - Mouse RIKEN cDNA 5730559C18 gene (5730559C18Rik) |
CNY 7,700.00 |
|
MR209867L4 | Lenti ORF clone of 5730559C18Rik (mGFP-tagged) - Mouse RIKEN cDNA 5730559C18 gene (5730559C18Rik) |
CNY 7,700.00 |
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