United States
Germany
Japan
United Kingdom
China
Keap1 (NM_001110307) Mouse Untagged Clone
CAT＃: MC219786
Keap1 (untagged) - Mouse kelch-like ECH-associated protein 1 (Keap1), transcript variant 4, (10ug)
CNY 7,980.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | INRF2; mKIAA0132 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC219786 representing NM_001110307
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCAGCCCGAACCCAAGCTTAGCGGGGCTCCCCGCAGCAGCCAGTTCCTGCCCCTGTGGTCAAAGTGCC CCGAGGGGGCCGGGGACGCAGTGATGTATGCCTCCACGGAGTGCAAGGCAGAGGTGACGCCCTCGCAGGA CGGTAACCGAACCTTCAGCTACACACTAGAGGATCACACCAAGCAGGCTTTTGGCGTCATGAACGAGCTT CGCCTGAGCCAGCAACTCTGTGACGTGACCCTGCAGGTCAAATATGAGGACATCCCAGCTGCCCAATTCA TGGCTCACAAAGTGGTGCTGGCCTCCTCCAGCCCAGTCTTTAAAGCCATGTTCACCAACGGGCTTCGGGA GCAGGGCATGGAGGTGGTGTCCATCGAAGGCATCCACCCTAAGGTCATGGAAAGGCTTATTGAGTTCGCC TACACGGCCTCCATCTCCGTGGGCGAGAAGTGTGTCCTGCACGTGATGAACGGGGCGGTCATGTACCAGA TTGACAGCGTGGTTCGAGCCTGCAGCGACTTCCTCGTGCAGCAGCTGGACCCCAGCAACGCCATTGGCAT CGCCAACTTCGCGGAGCAGATCGGCTGCACTGAACTGCACCAGCGTGCCCGGGAGTATATCTACATGCAC TTCGGGGAGGTGGCCAAGCAGGAGGAGTTCTTCAACCTGTCACACTGCCAGCTGGCCACGCTCATCAGCC GGGATGATCTGAACGTACGCTGCGAGTCCGAGGTGTTCCACGCGTGCATCGACTGGGTCAAATACGACTG CCCGCAGCGGCGCTTCTACGTGCAGGCACTGCTGCGGGCCGTGCGCTGCCATGCGCTCACGCCGCGCTTC CTGCAGACGCAGCTGCAGAAGTGTGAGATCCTGCAGGCCGACGCGCGCTGCAAGGACTACCTGGTGCAGA TATTCCAGGAGCTCACGCTGCACAAGCCCACGCAGGCAGTGCCCTGCCGCGCGCCCAAAGTGGGCCGCCT CATCTACACAGCGGGCGGTTACTTCCGACAGTCGCTCAGCTACCTGGAGGCCTACAACCCGAGCAATGGC TCCTGGCTGCGCCTGGCCGATCTACAGGTGCCGCGCAGTGGGCTGGCAGGCTGCGTGGTGGGTGGGCTGC TATACGCTGTGGGCGGCCGCAACAACTCTCCGGATGGCAACACTGACTCCAGCGCCCTGGACTGCTACAA CCCCATGACCAACCAGTGGTCGCCCTGTGCCTCTATGAGCGTGCCACGCAACCGCATCGGGGTGGGGGTC ATAGATGGCCACATCTACGCAGTCGGGGGTTCCCACGGCTGCATCCACCACAGCAGCGTGGAGAGATATG AGCCAGAGCGGGACGAGTGGCATCTAGTCGCGCCAATGTTGACACGGAGGATTGGCGTGGGCGTGGCAGT GCTCAACCGCTTGCTGTATGCAGTGGGGGGCTTTGACGGGACTAACCGGCTTAACTCCGCAGAATGTTAC TATCCAGAGAGGAATGAGTGGCGGATGATCACACCGATGAATACCATCCGGAGCGGGGCCGGGGTCTGCG TGCTGCACAACTGTATCTATGCAGCAGGGGGCTACGATGGGCAGGACCAGTTGAACAGTGTGGAGCGCTA CGACGTGGAGACAGAGACCTGGACTTTCGTAGCCCCCATGAGGCATCACCGTAGTGCGCTGGGGATTACT GTGCACCAGGGCAAGATCTACGTCCTCGGAGGCTATGATGGCCACACTTTTCTGGACAGTGTGGAATGCT ATGACCCGGACAGTGATACCTGGAGTGAGGTGACCCGCATGACATCTGGCCGCAGCGGGGTGGGTGTGGC CGTCACCATGGAACCCTGTCGGAAGCAAATTGATCAACAAAACTGTACCTGCTGA AGCGGACCGACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCC TGGATTACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-RsrII |
| ACCN | NM_001110307 |
| Insert Size | 1875 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001110307.1, NP_001103777.1 |
| RefSeq Size | 3151 bp |
| RefSeq ORF | 1875 bp |
| Locus ID | 50868 |
| UniProt ID | Q9Z2X8 |
| Gene Summary | Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome (By similarity).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (4) uses a different splice site in the 5' UTR, compared to variant 1. Variants 1, 2, 3, and 4 all encode the same protein. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MR209525 | Keap1 (Myc-DDK-tagged) - Mouse kelch-like ECH-associated protein 1 (Keap1), transcript variant 4 |
CNY 6,976.00 |
|
| MR209525L1 | Lenti ORF clone of Keap1 (Myc-DDK-tagged) - Mouse kelch-like ECH-associated protein 1 (Keap1), transcript variant 4 |
CNY 9,376.00 |
|
| MR209525L2 | Lenti ORF clone of Keap1 (mGFP-tagged) - Mouse kelch-like ECH-associated protein 1 (Keap1), transcript variant 4 |
CNY 9,376.00 |
|
| MR209525L3 | Lenti ORF clone of Keap1 (Myc-DDK-tagged) - Mouse kelch-like ECH-associated protein 1 (Keap1), transcript variant 4 |
CNY 6,460.00 |
|
| MR209525L4 | Lenti ORF clone of Keap1 (mGFP-tagged) - Mouse kelch-like ECH-associated protein 1 (Keap1), transcript variant 4 |
CNY 6,460.00 |
