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Mtm1 (NM_001164192) Mouse Untagged Clone
CAT＃: MC219168
Mtm1 (untagged) - Mouse X-linked myotubular myopathy gene 1 (Mtm1), transcript variant 4, (10ug)
CNY 7,320.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | AF073996; mKIAA4176; Mtm |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC219168 representing NM_001164192
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCTTCTGCATCAGCATCTAAGTATAATTCACACTCCTTGGAGAATGAATCCATTAAGAAAGTGTCTC AAGATGGAGTCAGTCAGGATGTGAGTGAGACTGTCCCTCGGCTCCCAGGGGAGTTACTAATTACTGAAAA AGAAGTTATTTACATATGTCCTTTCAATGGCCCCATTAAGGGAAGAGTTTACATCACAAATTATCGTCTT TATTTAAGAAGTTTGGAAACGGATTCTGCTCTAATACTTGATGTTCCTCTGGGTGTGATATCAAGAATTG AAAAAATGGGAGGCGCGACAAGTAGAGGAGAAAATTCCTATGGTCTAGATATTACTTGTAAAGATTTGAG AAACCTGAGGTTTGCATTGAAGCAAGAAGGCCACAGCAGAAGAGATATGTTTGAGATCCTTGTAAAACAT GCCTTTCCTCTGGCACACAATCTGCCATTATTTGCATTTGTAAATGAAGAGAAGTTTAACGTGGATGGGT GGACTGTTTATAATCCAGTTGAAGAATATAGAAGGCAGGGCCTGCCCAATCACCATTGGAGGATAAGTTT TATTAACAAGTGCTATGAGCTCTGTGAGACATACCCTGCTCTTTTGGTGGTTCCCTATCGGACCTCAGAT GATGATCTTAGGAGGATCGCAACGTTTAGATCCCGAAATCGGCTTCCTGTACTGTCGTGGATTCACCCAG AAAACAAAATGGTCATTATGCGCTGCAGTCAGCCTCTTGTCGGTATGAGTGGTAAAAGAAATAAAGATGA CGAGAAATACCTGGATGTGATCAGGGAAACTAACAAACAAACTTCTAAGCTCATGATTTATGATGCACGA CCCAGTGTAAATGCAGTCGCCAACAAGGCAACAGGAGGAGGATATGAAAGTGATGACGCATATCAAAACT CAGAACTTTCCTTCTTAGACATTCATAATATTCATGTTATGCGAGAATCTTTAAAAAAAGTGAAAGATAT TGTTTATCCCAACATAGAAGAATCTCATTGGTTGTCCAGTTTGGAGTCTACTCATTGGTTAGAACATATC AAGCTTGTTCTGACCGGTGCCATTCAAGTGGCAGACCAAGTGTCTTCAGGAAAGAGCTCGGTACTTGTGC ACTGCAGTGACGGATGGGACAGGACCGCTCAGCTGACATCCTTGGCCATGCTGATGTTGGACAGCTTCTA CAGAACTATTGAAGGCTTTGAGATATTGGTACAGAAAGAGTGGATAAGTTTTGGCCATAAATTTGCATCT TTCCCCACAGCTTTTGAGTTCAATGAAGGCTTTTTGATTACCGTTTTGGATCATCTGTATAGCTGTCGAT TTGGTACTTTCTTATTCAACTGTGACTCGGCTCGAGAAAGACAGAAACTTACAGAAAGAACAGTTTCTCT ATGGTCGCTAATTAACAGCAATAAAGACAAATTCAAAAACCCCTTCTATACAAAAGAAATCAATCGGGTT TTGTATCCAGTTGCCAGCATGCGTCACTTGGAACTGTGGGTGAATTATTACATCCGATGGAATCCCAGGG TCAAGCAGCAACAGCCCAACCCAGTGGAGCAGCGTTACATGGAGCTTTTGGCCTTGCGTGACGATTATAT AAAGAGGCTCGAGGAATTGCAGCTGGCCAACTCCGCCAAGCTTGCTGATGCCCCCGCTTCGACTTCCAGT TCGTCACAGATGGTGCCCCATGTGCAGACGCACTTCTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001164192 |
| Insert Size | 1719 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001164192.1, NP_001157664.1 |
| RefSeq Size | 3286 bp |
| RefSeq ORF | 1719 bp |
| Locus ID | 17772 |
| UniProt ID | Q9Z2C5 |
| Gene Summary | Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate (PI3P) and phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2). Has also been shown to dephosphorylate phosphotyrosine- and phosphoserine-containing peptides. Negatively regulates EGFR degradation through regulation of EGFR trafficking from the late endosome to the lysosome. Plays a role in vacuolar formation and morphology (By similarity). Regulates desmin intermediate filament assembly and architecture. Plays a role in mitochondrial morphology and positioning (PubMed:21135508). Required for skeletal muscle maintenance but not for myogenesis (PubMed:12391329). In skeletal muscles, stabilizes MTMR12 protein levels (PubMed:23818870).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (4) differs in the 5' UTR and lacks an alternate in-frame exon in the 3' coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG223846 | Mtm1 (tGFP-tagged) - Mouse X-linked myotubular myopathy gene 1 (Mtm1) transcript variant 4, (10ug) |
CNY 6,270.00 |
|
| MR223846 | Mtm1 (Myc-DDK-tagged) - Mouse X-linked myotubular myopathy gene 1 (Mtm1), transcript variant 4 |
CNY 5,700.00 |
|
| MR223846L3 | Lenti ORF clone of Mtm1 (Myc-DDK-tagged) - Mouse X-linked myotubular myopathy gene 1 (Mtm1), transcript variant 4 |
CNY 7,600.00 |
|
| MR223846L4 | Lenti ORF clone of Mtm1 (mGFP-tagged) - Mouse X-linked myotubular myopathy gene 1 (Mtm1), transcript variant 4 |
CNY 7,600.00 |
