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Ppp5c (NM_011155) Mouse Untagged Clone
CAT＃: MC216972
Ppp5c (untagged) - Mouse protein phosphatase 5, catalytic subunit (Ppp5c), (10ug)
CNY 6,460.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | AU020526; PP5 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC216972 representing NM_011155
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCGATGGCGGAGGGCGAGCGGACTGAGTGTGCTGAGACCCCCCGGGACGAACCCCCGGCCGATGGCA CTCTGAAGCGGGCAGAGGAGCTCAAGACACAGGCCAACGACTACTTCAAAGCCAAGGACTACGAGAACGC GATCAAGTTCTACAGTCAGGCCATCGAGTTGAACCCCGGCAATGCCATCTACTATGGCAACCGCAGCCTG GCCTACCTGCGCACTGAGTGCTATGGCTATGCACTGGGCGACGCCACACGGGCCATCGAGCTTGACAAGA AGTACATCAAAGGCTACTACCGCCGGGCGGCCAGCAACATGGCACTGGGCAAGTTCCGGGCTGCCCTGCG TGACTACGAGACGGTGGTGAAAGTGAAGCCTAATGACAAGGATGCCAAGATGAAGTACCAGGAGTGCAGC AAGATTGTGAAGCAGAAGGCCTTTGAGAGGGCCATTGCGGGTGACGAGCACAGACGCTCTGTCGTGGACT CTCTGGACATTGAAAGCATGACCATTGAAGATGAGTACAGCGGGCCCAAGCTTGAGGATGGCAAAGTGAC AATCACCTTCATGAAAGACCTCATGCAGTGGTACAAGGATCAGAAGAAACTGCACCGGAAGTGCGCCTAC CAGATCCTAGTACAGGTGAAAGAAGTCCTCTGCAAGCTGAGCACGCTGGTGGAGACGACGCTGAAAGAGA CAGAGAAGATTACAGTGTGCGGGGACACCCATGGCCAGTTCTACGACCTCCTCAACATATTTGAGCTCAA CGGTTTACCCTCAGAGACCAACCCCTATATATTTAATGGCGATTTTGTGGACCGTGGTTCCTTCTCCGTT GAAGTGATCCTCACCCTCTTCGGCTTTAAGCTCCTGTATCCAGATCATTTCCATCTACTTCGAGGCAACC ACGAGACAGACAACATGAACCAGATCTACGGGTTCGAGGGCGAGGTGAAGGCCAAGTACACAGCCCAGAT GTATGAGCTCTTCAGCGAGGTGTTCGAGTGGCTTCCGCTGGCGCAGTGTATCAATGGCAAAGTGCTGATC ATGCACGGAGGCCTATTCAGCGAAGATGGTGTCACTCTGGATGACATCCGAAAGATTGAGCGGAATCGGC AGCCCCCAGACTCAGGTCCCATGTGTGACCTGCTGTGGTCAGATCCCCAGCCACAGAATGGGCGCTCCGT CAGCAAGCGTGGTGTGAGTTGCCAGTTTGGGCCTGATGTCACCAAGGCCTTCCTGGAGGAGAATCAACTG GACTATATCATCCGCAGCCATGAAGTCAAAGCCGAGGGCTACGAGGTGGCCCATGGTGGCCGCTGTGTCA CTGTCTTTTCTGCCCCCAACTATTGTGACCAGATGGGAAACAAAGCCTCCTACATCCACCTCCAGGGCTC CGACCTGCGGCCCCAGTTCCACCAATTCACAGCAGTGCCTCACCCCAATGTCAAGCCCATGGCATACGCC AACACGCTTCTGCAGCTAGGAATGATGTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_011155 |
| Insert Size | 1500 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_011155.2, NP_035285.2 |
| RefSeq Size | 2084 bp |
| RefSeq ORF | 1500 bp |
| Locus ID | 19060 |
| UniProt ID | Q60676 |
| Gene Summary | Serine/threonine-protein phosphatase that dephosphorylates a myriad of proteins involved in different signaling pathways including the kinases CSNK1E, ASK1/MAP3K5, PRKDC and RAF1, the nuclear receptors NR3C1, PPARG, ESR1 and ESR2, SMAD proteins and TAU/MAPT. Implicated in wide ranging cellular processes, including apoptosis, differentiation, DNA damage response, cell survival, regulation of ion channels or circadian rhythms, in response to steroid and thyroid hormones, calcium, fatty acids, TGF-beta as well as oxidative and genotoxic stresses. Participates in the control of DNA damage response mechanisms such as checkpoint activation and DNA damage repair through, for instance, the regulation ATM/ATR-signaling and dephosphorylation of PRKDC and TP53BP1. Inhibits ASK1/MAP3K5-mediated apoptosis induced by oxidative stress. Plays a positive role in adipogenesis, mainly through the dephosphorylation and activation of PPARG transactivation function. Also dephosphorylates and inhibits the anti-adipogenic effect of NR3C1. Regulates the circadian rhythms, through the dephosphorylation and activation of CSNK1E. May modulate TGF-beta signaling pathway by the regulation of SMAD3 phosphorylation and protein expression levels. Dephosphorylates and may play a role in the regulation of TAU/MAPT. Through their dephosphorylation, may play a role in the regulation of ions channels such as KCNH2.[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG208000 | Ppp5c (tGFP-tagged) - Mouse protein phosphatase 5, catalytic subunit (Ppp5c) |
CNY 3,710.00 |
|
| MR208000 | Ppp5c (Myc-DDK-tagged) - Mouse protein phosphatase 5, catalytic subunit (Ppp5c) |
CNY 3,656.00 |
|
| MR208000L3 | Lenti ORF clone of Ppp5c (Myc-DDK-tagged) - Mouse protein phosphatase 5, catalytic subunit (Ppp5c) |
CNY 5,230.00 |
|
| MR208000L4 | Lenti ORF clone of Ppp5c (mGFP-tagged) - Mouse protein phosphatase 5, catalytic subunit (Ppp5c) |
CNY 5,230.00 |
