Birc7 (NM_001163247) Mouse Untagged Clone

CAT#: MC214562

Birc7 (untagged) - Mouse baculoviral IAP repeat-containing 7 (livin) (Birc7), (10ug)



  "NM_001163247" in other vectors (4)

CNY 3,990.00


货期*
4周

规格
    • 10 ug

Product images

经常一起买 (3)
TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Mouse Untagged Clone
Tag Tag Free
Synonyms E130019N06; KIAP; Livin; ML-IAP
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>MC214562 representing NM_001163247
Red=Cloning site Blue=ORF Orange=Stop codon

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGTTCTCACCTGCAGACTTATTCAGAGCTGCTGTCTTTTCCATGGGGCCTGAGAGTAGGGCCAGGGACT
CGGTCCGTGGCCCAGAACTAAGCCACAGGGAAGATGGCAGTGGCCGCACACAGGAACAGGATAAACCCCA
CTGTCCGTGTAACCATGTCCTGGGCCAGGACTGCCTAGATGGGCAGATCTTAGGCCAGCTTCGGCCTCTG
TCAGAAGAGGAAGAATCCTCTGGGGCTGCCTTCCTTGGGGAGCCTGCCTTCCCTGAGATGGACTCAGAGG
ATCTCCGGCTAGCCTCCTTCTACGACTGGCCATCTACTGCAGGGATTCAGCCTGAGCCATTGGCTGCTGC
TGGGTTCTTCCACACAGGCCAGCAGGACAAGGTGAGATGTTTCTTCTGCTATGGGGGTCTACAGAGCTGG
GAGCGTGGGGATGACCCCTGGACAGAGCATGCCCGATGGTTTCCCAGGTGTCAGTTCCTGCTACGGTCAA
AAGGAAGGGACTTTGTGGAAAGAATCCAGACCTACACCCCTTTGCTGGGATCCTGGGATCAGCGAGAAGA
ACCAGAAGATGCAGTCTCTGCCACTCCCTCAGCTCCTGCCCATGGAAGCCCTGAGTTACTCAGATCCAGA
AGAGAGACCCAGCCTGAAGATGTCAGTGAGCCAGGAGCCAAGGATGTTCAGGAACAGCTGCGACAGCTGC
AGGAAGAGAGGAGATGCAAGGTGTGCCTGGACCGAGCCGTCTCCATAGTCTTCGTGCCCTGTGGCCACTT
CGTCTGCACCGAGTGTGCTCCCAACCTGCAGCTGTGCCCTATCTGCAGGGTGCCTATCTGTAGCTGTGTA
CGCACATTCCTGTCCTAA


ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
ACAAGGATGACGACGATAAGGTTTAA
Restriction Sites SgfI-MluI     
ACCN NM_001163247
Insert Size 858 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_001163247.1, NP_001156719.1
RefSeq Size 1178 bp
RefSeq ORF 858 bp
Locus ID 329581
UniProt ID A2AWP0
Gene Summary Apoptotic regulator capable of exerting proapoptotic and anti-apoptotic activities and plays crucial roles in apoptosis, cell proliferation, and cell cycle control. Its anti-apoptotic activity is mediated through the inhibition of caspase-3, -7, and -9, as well as by its E3 ubiquitin-protein ligase activity. As it is a weak caspase inhibitor, its anti-apoptotic activity is thought to be due to its ability to ubiquitinate DIABLO/SMAC targeting it for degradation thereby promoting cell survival. May contribute to caspase inhibition, by blocking the ability of DIABLO/SMAC to disrupt XIAP/BIRC4-caspase interactions. Protects against apoptosis induced by TNF or by chemical agents such as adriamycin, etoposide or staurosporine. Suppression of apoptosis is mediated by activation of MAPK8/JNK1, and possibly also of MAPK9/JNK2. This activation depends on TAB1 and NR2C2/TAK1.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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