Ackr4 (NM_145700) Mouse Untagged Clone

CAT#: MC213257

Ackr4 (untagged) - Mouse chemokine (C-C motif) receptor-like 1 (Ccrl1), (10ug)



  "NM_145700" in other vectors (6)

CNY 3,990.00


货期*
4周

规格
    • 10 ug

Product images

经常一起买 (3)
TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Mouse Untagged Clone
Tag Tag Free
Synonyms A630091E18Rik; CCBP2; CCR11; Ccrl1; CCX-CKR; CCX-CKR1; Cmkbrl1; PPR1; VSHK1
Vector pCMV6-Entry
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>MC213257 representing NM_145700
Red=Cloning site Blue=ORF Orange=Stop codon

TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC
GCCGCGATCGCC

ATGGCTCTGGAGCTGAACCAGTCAGCGGAATACTATTATGAGGAGAATGAGATGAACTACACTCACGACT
ACAGCCAGTACGAAGTGATCTGCATAAAAGAAGAGGTCAGGCAGTTCGCAAAAGTCTTCCTGCCTGCCTT
CTTCACAGTGGCCTTTGTCACTGGGCTCGCAGGGAACTCCGTAGTTGTGGCGATTTACGCCTATTACAAG
AAGCAGAGGACCAAGACCGATGTGTACATCCTGAACCTGGCTGTAGCAGACTTGTTACTTCTGATCACGC
TGCCTTTCTGGGCAGTTAATGCAGTTCACGGATGGATTCTAGGCAAAATGATGTGCAAAGTAACGTCAGC
CCTGTACACGGTAAACTTTGTCTCTGGGATGCAGTTCCTGGCTTGTATCAGCATTGACAGATATTGGGCA
ATTACCAAAGCCCCCAGCCAATCAGGAGCGGGGAGACCCTGTTGGATCATCTGTTGCTGTGTGTGGATGG
CCGCCATCTTGCTGAGCATACCCCAGCTGGTTTTTTACACAGTGAATCAGAATGCTAGGTGCACTCCCAT
CTTTCCCCACCACCTAGGAACATCCCTGAAAGCATCCATTCAGATGCTGGAAATCGGCATCGGCTTTGTG
GTCCCGTTTCTCATCATGGGCGTGTGCTATGCCAGTACCGCCAGGGCGCTCATCAAGATGCCCAACATTA
AAAAGTCTCGCCCCCTCAGGGTTCTGCTCGCGGTGGTGGTGGTTTTCATTGTCACCCAGCTGCCCTATAA
CGTTGTTAAGTTCTGCCAAGCCATAGATGCCATCTACCTGCTGATCACCAGCTGCGATATGAGCAAACGC
ATGGATGTCGCCATCCAAGTCACAGAGAGCATCGCGCTCTTCCACAGCTGCCTCAACCCCATCCTGTATG
TCTTCATGGGGGCCTCCTTCAAAAACTATATCATGAAAGTGGCCAAGAAATATGGATCCTGGAGAAGACA
GAGACAGAACGTGGAAGAAATTCCTTTTGATTCTGAGGGTCCTACAGAGCCAACCAGTTCTTTTACCATT
TAA


ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT
ACAAGGATGACGACGATAAGGTTTAA
Restriction Sites SgfI-MluI     
ACCN NM_145700
Insert Size 1053 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq NM_145700.2, NP_663746.2
RefSeq Size 2109 bp
RefSeq ORF 1053 bp
Locus ID 252837
UniProt ID Q924I3
Gene Summary Atypical chemokine receptor that controls chemokine levels and localization via high-affinity chemokine binding that is uncoupled from classic ligand-driven signal transduction cascades, resulting instead in chemokine sequestration, degradation, or transcytosis. Also known as interceptor (internalizing receptor) or chemokine-scavenging receptor or chemokine decoy receptor. Acts as a receptor for chemokines CCL2, CCL8, CCL13, CCL19, CCL21 and CCL25. Chemokine-binding does not activate G-protein-mediated signal transduction but instead induces beta-arrestin recruitment, leading to ligand internalization. Plays an important role in controlling the migration of immune and cancer cells that express chemokine receptors CCR7 and CCR9, by reducing the availability of CCL19, CCL21, and CCL25 through internalization. Negatively regulates CXCR3-induced chemotaxis. Regulates T-cell development in the thymus and inhibits spontaneous autoimmunity.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Other Versions

Customer Reviews 
Loading...