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Kmt5b (NM_001167884) Mouse Untagged Clone
CAT＃: MC212767
Suv420h1 (untagged) - Mouse suppressor of variegation 4-20 homolog 1 (Drosophila) (Suv420h1), transcript variant 7, (10ug)
CNY 3,990.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | AA117471; C630029K18Rik; Suv4-20h1; Suv420h1 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>NM_001167884.1
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGAAGTGGTTGGGAGACTCCAAGAACATGGTGGTGAATGGCAGGAGAAATGGAGGCAAGTTGTCTAATG ACCATCAGCAGAATCAATCAAAATTACAGCAGCACTCGGGCAAGGACACCCTGAAGACCGGCAGAAACGC CGTTGAGAGGCGGTCCAGCAGATGTCATGGTAACTCGGGATTTGAAGGGCAGAGCCGCTATGTGCCGTCC TCTGGAATGTCCGCCAAGGAGCTCTGTGAGAACGATGACTTAGCAACCAGTTTGGTTCTTGATCCCTACT TAGGTTTTCAGACACACAAAATGAACACTAGCGCCTTTCCTTCGAGGAGCTCGAGGCATATTTCAAAAGC TGACAGTTTTTCTCACAACAATCCTGTGAGATTTCGGCCTATAAAAGGAAGGCAAGAAGAGCTAAAGGAA GTAATTGAACGCTTTAAGAAAGATGAACACTTAGAGAAAGCTTTCAAATGTTTGACTTCTGGGGAATGGG CACGGCATTATTTTCTCAACAAAAACAAAATGCAGGAGAAATTATTCAAGGAACATGTCTTTATTTACTT GCGGATGTTTGCAACTGACAGTGGATTTGAAATACTGCCTTGTAATAGATATTCTTCAGAACAAAATGGA GCCAAGATAGTTGCAACAAAAGAGTGGAAACGAAATGACAAAATAGAATTACTGGTGGGTTGTATTGCCG AACTTTCAGAAATTGAGGAGAACATGCTACTTAGACACGGAGAAAACGACTTCAGTGTCATGTATTCCAC AAGGAAAAATTGTGCTCAACTCTGGCTCGGTCCTGCTGCATTTATAAATCATGATTGCAGACCTAACTGT AAGTTTGTGTCAACTGGTCGAGATACAGCATGCGTTAAGGCTCTGAGAGATATTGAACCTGGAGAAGAAA TTTCTTGTTACTATGGAGATGGCTTTTTTGGAGAAAATAATGAGTTCTGCGAATGTTATACTTGTGAAAG GTAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCTGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001167884 |
| Insert Size | 984 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001167884.1, NP_001161356.1 |
| RefSeq Size | 3318 bp |
| RefSeq ORF | 984 bp |
| Locus ID | 225888 |
| UniProt ID | Q3U8K7 |
| Gene Summary | Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. KMT5B is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2). Plays a role in myogenesis by regulating the expression of target genes, such as EID3.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (7) differs in the 5' UTR, the 3' UTR, and the 3' coding sequence compared to variant 1. The resulting isoform (d) has a shorter C-terminus compared to isoform a. Variants 6 and 7 both encode isoform d. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG218821 | Suv420h1 (tGFP-tagged) - Mouse suppressor of variegation 4-20 homolog 1 (Drosophila) (Suv420h1) transcript variant 7, (10ug) |
CNY 2,850.00 |
|
| MR218821 | Suv420h1 (Myc-DDK-tagged) - Mouse suppressor of variegation 4-20 homolog 1 (Drosophila) (Suv420h1), transcript variant 7 |
CNY 2,400.00 |
|
| MR218821L3 | Lenti ORF clone of Suv420h1 (Myc-DDK-tagged) - Mouse suppressor of variegation 4-20 homolog 1 (Drosophila) (Suv420h1), transcript variant 7 |
CNY 4,750.00 |
|
| MR218821L4 | Lenti ORF clone of Suv420h1 (mGFP-tagged) - Mouse suppressor of variegation 4-20 homolog 1 (Drosophila) (Suv420h1), transcript variant 7 |
CNY 4,750.00 |
