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Sytl2 (NM_001040088) Mouse Untagged Clone
CAT＃: MC211966
Sytl2 (untagged) - Mouse synaptotagmin-like 2 (Sytl2), transcript variant 5, (10ug)
CNY 3,990.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | AI266830; mKIAA1597; Slp2 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC211966 representing NM_001040088
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGAGCAAGTCCGTGCCAGCATTTCTTCAAGATGAGGCGAGTGGCAGTGTGATGAGCGTTTACAGTGGAG ACTTTGGCAACCTAGAAGTGAAAGGAAGCGTGCAGTTTGCACTCGACTACGTGGAGTCCCTGAAAGAGCT GCATGTGTTTGTGGCCCAGTGTAAGGATTTAGCAGCAGCAGATGTTAAGAAACAGCGCTCAGATCCGTAT GTAAAGACCTATCTGCTACCAGACAAAGGCAAAATGGGCAAGAAGAAGACACTCGTAGTGAAGAAGACCT TGAATCCTGTATACAACGAGATATTGCGGTATAAAATTGAAAGGCAATTCTTAAAGACGCAGAAGTTGAA CCTGTCCGTTTGGCATCGGGATACATTTAAGCGCAACAGCTTTCTGGGGGAGGTGGAGCTCGACCTGGAA ACGTGGGATTGGGACAGCAAACAGAACAAACAGCTGAAGTGGTACCCACTGAAGAGGAAGACAGCACCAG TTGCCCTCGAGACAGAAAACAGAGGTGAAATGAAACTAGCTCTCCAGTATGTTCCGGAACCAAGCCCTGG CAAAAAGCTTCCTACAACTGGAGAAGTCCACATCTGGGTGAAGGAATGCCTTGACCTCCCACTGTTGAGG GGCAGCCACCTAAATTCTTTTGTTAAATGTACCATCCTTCCAGATACCAGTAGAAAAAGTCGCCAGAAGA CAAGAGCTGTAGGGAAAACCACCAACCCCGTCTTCAACCATACCATGGTGTATGATGGGTTCAGGCCTGA AGATCTGATGGAAGCCTGTGTAGAACTCACAGTCTGGGACCATTATAAACTAACCAACCAGTTTCTGGGA GGTCTCCGGATCGGCTTTGGAACAGGAAAAAGCTACGGGACTGAAGTGGATTGGATGGATTCTACTTCTG AGGAAGTTGCTCTCTGGGAGAAGATGGTAAACTCTCCCAACACTTGGGTTGAAGCGACGCTGCCCCTCCG GATGCTTCTGATTGCCAAGCTTTCCAAGTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001040088 |
| Insert Size | 1011 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001040088.2, NP_001035177.1 |
| RefSeq Size | 2866 bp |
| RefSeq ORF | 1011 bp |
| Locus ID | 83671 |
| UniProt ID | Q99N50 |
| Gene Summary | Isoform 11 acts as a RAB27A effector protein and plays a role in cytotoxic granule exocytosis in lymphocytes. Required for cytotoxic granule docking at the immunologic synapse. Isoform 1 may play a role in melanosome transport and vesicle trafficking. It controls melanosome distribution in the cell periphery and regulates melanocyte morphology. Isoform 1 acts as a positive mediator of mucus secretion by the surface mucus cells of the stomach. Mediates basal mucus secretion by gastric surface cells by promoting the proper granule biognesis and docking of mucus granules with the apical plasma membrane.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (5) lacks several 5' exons but contains an alternate 5' exon, it lacks an internal in-frame exon, and it thus differs in its 5' UTR, lacks a portion of the 5' coding region, and initiates translation from a downstream in-frame start codon, compared to variant 6. The encoded isoform (5) is shorter at the N-terminus, compared to isoform 6. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG216915 | Sytl2 (tGFP-tagged) - Mouse synaptotagmin-like 2 (Sytl2) transcript variant 5, (10ug) |
CNY 10,070.00 |
|
| MR216915 | Sytl2 (Myc-DDK-tagged) - Mouse synaptotagmin-like 2 (Sytl2), transcript variant 5 |
CNY 9,120.00 |
|
| MR216915L3 | Lenti ORF clone of Sytl2 (Myc-DDK-tagged) - Mouse synaptotagmin-like 2 (Sytl2), transcript variant 5 |
CNY 11,020.00 |
|
| MR216915L4 | Lenti ORF clone of Sytl2 (mGFP-tagged) - Mouse synaptotagmin-like 2 (Sytl2), transcript variant 5 |
CNY 11,020.00 |
