United States
Germany
Japan
United Kingdom
China
Izumo1 (NM_001018013) Mouse Untagged Clone
CAT＃: MC211426
Izumo1 (untagged) - Mouse izumo sperm-egg fusion 1 (Izumo1), (10ug)
CNY 3,990.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 1700058F15Rik; Izumo |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC211426 representing NM_001018013
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGGGCCGCATTTTACACTCTTGCTGGCAGCTCTTGCCAACTGCCTGTGTCCAGGGAGGCCCTGCATCA AATGTGACCAGTTTGTGACAGATGCGCTAAAGACTTTCGAAAACACTTACCTGAATGACCACCTGCCACA CGACATTCACAAAAATGTAATGAGGATGGTGAACCATGAAGTATCGAGCTTCGGCGTAGTCACTTCGGCT GAGGATTCCTATTTGGGGGCCGTGGACGAGAACACACTGGAACAAGCAACCTGGAGTTTTCTGAAGGATC TGAAGCGTATTACAGACAGTGACTTAAAAGGAGAGCTCTTTATAAAGGAACTATTGTGGATGCTTCGTCA TCAAAAGGACATCTTTAACAATCTTGCTAGACAGTTCCAAAAGGAAGTTCTTTGTCCCAACAAATGCGGA GTGATGTCGCAGACTTTGATCTGGTGTCTTAAGTGCGAAAAGCAGTTGCACATTTGTCGGAAATCCCTAG ATTGTGGAGAGCGCCACATAGAGGTACATCGCTCGGAAGACCTGGTCCTGGACTGTCTGCTCAGTTGGCA TCGTGCTTCTAAGGGACTTACAGATTACAGTTTTTACAGGGTTTGGGAGAACAGTTCTGAGACCTTGATT GCCAAGGGGAAAGAACCATATCTGACCAAGTCGATGGTGGGTCCAGAGGATGCTGGCAACTACCGCTGTG TGCTAGATACCATCAACCAAGGTCATGCCACCGTCATCCGCTACGATGTCACAGTATTGCCCCCAAAGCA TTCAGAGGAAAACCAACCACCGAACATCATAACCCAAGAGGAGCACGAGACTCCTGTCCACGTGACTCCA CAGACACCACCGGGGCAGGAGCCAGAGTCGGAGCTGTACCCGGAGCTGCACCCAGAGTTGTACCCGGAGC TCATACCTACAGTCGCTCAAAATCCAGAGAAAAAAATGAAAACTCGCCTCTTAATACTGTTGACCCTTGG CTTTGTGGTTCTTGTGGCCAGCATCATTATCTCGGTACTTCACTTTAGGAAAGTCAGCGCTAAATTGAAG AATGCAAGTGACGAAGTCAAACCCACCGCGTCAGGATCCAAGTCAGATCAGAGTTTGTCCCAACAGATGG GATTGAAGAAGGCCTCTCAGGCAGATTTTAACTCTGACTACTCTGGAGATAAGAGCGAGGCAACAGAAAA CTAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001018013 |
| Insert Size | 1194 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001018013.1, NP_001018013.1 |
| RefSeq Size | 1493 bp |
| RefSeq ORF | 1194 bp |
| Locus ID | 73456 |
| UniProt ID | Q9D9J7 |
| Gene Summary | Essential sperm cell-surface protein required for fertilization by acting as a ligand for IZUMO1R/JUNO receptor on egg (PubMed:15759005, PubMed:24739963, PubMed:27309808). The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion (PubMed:15759005, PubMed:24739963, PubMed:27309808). The ligand-receptor interaction probably does not act as a membrane 'fusogen' (PubMed:15759005, PubMed:24739963, PubMed:27309808).[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG222708 | Izumo1 (tGFP-tagged) - Mouse izumo sperm-egg fusion 1 (Izumo1), (10ug) |
CNY 7,088.00 |
|
| MR222708 | Izumo1 (Myc-DDK-tagged) - Mouse izumo sperm-egg fusion 1 (Izumo1) |
CNY 5,488.00 |
|
| MR222708L3 | Lenti ORF clone of Izumo1 (Myc-DDK-tagged) - Mouse izumo sperm-egg fusion 1 (Izumo1) |
CNY 5,890.00 |
|
| MR222708L4 | Lenti ORF clone of Izumo1 (mGFP-tagged) - Mouse izumo sperm-egg fusion 1 (Izumo1) |
CNY 5,890.00 |
