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Abraxas1 (NM_172405) Mouse Untagged Clone
CAT＃: MC211092
Fam175a (untagged) - Mouse family with sequence similarity 175, member A (Fam175a), (10ug)
CNY 3,990.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 3830405G04Rik; 5630400M01Rik; AI506069; AL024423; AV118690; Ccdc98 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC211092 representing NM_172405
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGAGGGCGAGAGCACGTTGGGGGTGCTGTCTGGCTTCGTGCTCGGCGCGCTCACTTTCCATCATCTCA ACACAGACTCAGACACGGAAGGTTTTCTCCTCGGTGAAATGAAAGGTGAAGCCAAGAATAGCATTACTGA TTCACAGATGGACAACGTTAAAGTTGTTTATACAATTGACATTCAGAAATATATCCCATGCTACCGGCTT TTTAGCTTTTATAATTCTTTAGGTGAAGTAAACGAACATGCACTGAAGAAGGTTCTTTCAAATGTCAGAA AGACTGTGGTGGGTTGGTATAAATTCCGTCGTCACTCGGATCAGATCATGACATTTAGAGAGCAGTTACT CCACAGAAACTTACAGACACATCTTTCAAGCCCTGAGCTGGTTTTCCTGTTGTTAACACCGAGTATAACA ACAGAAAGCTGCTCCACTCACTGCCTGGAACACGCCTTATATAAACCTCAAAGGGGGCTTTTTCATAGGG TACCATTGGTGGTTACCAATCTGGGAATGTCTGATCAACTGGGTTATAAAACAGAACCTGCTTCCTGTAC GTCCACTGTCTTTAGTAGAGCTGTGAGGACACACAGTTCTCAGTTCTTTAATGAAGATGGATCATTAAAG GAAGTCCATAAGATAAATGAAATGTATGCTGCTGTACAAGAAGAGTTAAAGAGTATATGCCAAAAAGTTG AACAAAGTGAACGAGAAGTAGAGAAACTATTGATGGATGTAAACCAATTAAAAGAAGTTAGAAGAACCCA GCAAGCACGGGCTACAGGAGCAGGAGAGAAGAATGTCCAGAGAAACCCACAGGAGAACATCCTTCTTTGT CAAGCTTTGCGAACATTTTTTCCAGAGTCTGAAGTTCTTCATTCTTGCGTTATTTCTTTGAAAAATAGAC ACATTTCTCCCAGTGGGTGTAACGTTAACCACCATGTTGATGTAGTGGATCAGCTGACCTTAATGGTAGA GTATGTGTACAGCCCTGAAGCTAGTCCAGTGCCCACAGCCCAGCTACGTAAACGGAAGGCTCTAGACACA CACGACCAGGGGTCTGTGAAGAGACCACGGCTGCTGGAGACAGAAAGCAGACCTTCTGTGGCAGCGTCCC GCAGCAGGCACCAAGACAAGGCTTCCTCAAGCAGCCTAGATATAGACATAGAGATGGGGAGCCCAGAAGA TGATGCTGACTATCCTCGCTCTCCCACATTTTAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_172405 |
| Insert Size | 1224 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_172405.3, NP_765993.1 |
| RefSeq Size | 2499 bp |
| RefSeq ORF | 1224 bp |
| Locus ID | 70681 |
| UniProt ID | Q8BPZ8 |
| Gene Summary | Involved in DNA damage response and double-strand break (DSB) repair. Component of the BRCA1-A complex, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1. The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs. This complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX.[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MR204136 | Fam175a (Myc-DDK-tagged) - Mouse family with sequence similarity 175, member A (Fam175a) |
CNY 2,400.00 |
|
| MR204136L3 | Lenti ORF clone of Fam175a (Myc-DDK-tagged) - Mouse family with sequence similarity 175, member A (Fam175a) |
CNY 4,750.00 |
|
| MR204136L4 | Lenti ORF clone of Fam175a (mGFP-tagged) - Mouse family with sequence similarity 175, member A (Fam175a) |
CNY 4,750.00 |
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