Mllt3 (NM_029931) Mouse Untagged Clone
CAT#: MC211043
Mllt3 (untagged) - Mouse myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila), translocated to, 3 (Mllt3), transcript variant 2, (10ug)
CNY 3,990.00
Product images
Specifications
Product Data | |
Type | Mouse Untagged Clone |
Tag | Tag Free |
Synonyms | 2210011H10Rik; 2610012I03Rik; 3830408D16Rik; Af9; D4Ertd321e |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>MC211043 representing NM_029931
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGAAAGATCTGCATTCTGATGACAACGAGGAGGAGTCTGATGAGGCAGAGGACAATGACAATGACTCGG AGATGGAAAGACCTGTAAATAGAGGAGGAAGCCGAAGTCGCAGGGTCAGCTTGAGTGACGGCAGTGACAG TGAAAGCAGCTCCGCCTCTTCCCCTCTCCATCATGAACCCCCGCCACCATTATTGAAAACTAACAACAAC CAGATCCTTGAAGTGAAAAGTCCAATAAAACAAAGCAAATCAGATAAGCAAATAAAGAATGGTGAATGTG ACAAGGCATATCTAGATGAGTTGGTAGAGCTCCACAGAAGGTTAATGACACTGAGGGAACGACACATTCT GCAGCAGATCGTGAACCTTATAGAGGAAACTGGACACTTTCATATTACGAATACAACATTTGATTTTGAT CTTTGCTCGCTGGACAAAACTACAGTCCGTAAATTACAGAGTTACCTGGAAACATCTGGAACATCCTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
Restriction Sites | SgfI-MluI |
ACCN | NM_029931 |
Insert Size | 489 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_029931.3, NP_084207.2 |
RefSeq Size | 4802 bp |
RefSeq ORF | 489 bp |
Locus ID | 70122 |
Gene Summary | Chromatin reader component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. Specifically recognizes and binds acylated histone H3, with a marked preference for histone H3 that is crotonylated. Crotonylation marks active promoters and enhancers and confers resistance to transcriptional repressors. Recognizes and binds histone H3 crotonylated at 'Lys-9' (H3K9cr), and with slightly lower affinity histone H3 crotonylated at 'Lys-18' (H3K18cr). Also recognizes and binds histone H3 acetylated at 'Lys-9' (H3K9ac), but with lower affinity than crotonylated histone H3. In the SEC complex, MLLT3 is required to recruit the complex to crotonylated histones.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) lacks several exons, uses an alternate 5' exon structure and initiates translation at a downstream start codon, compared to variant 1. It encodes isoform 2, which is shorter than isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MR208832 | Mllt3 (Myc-DDK-tagged) - Mouse myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila), translocated to, 3 (Mllt3), transcript variant 2 |
CNY 5,610.00 |
|
MR208832L3 | Lenti ORF clone of Mllt3 (Myc-DDK-tagged) - Mouse myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 (Mllt3), transcript variant 2 |
CNY 7,510.00 |
|
MR208832L4 | Lenti ORF clone of Mllt3 (mGFP-tagged) - Mouse myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 (Mllt3), transcript variant 2 |
CNY 7,510.00 |