United States
Germany
Japan
United Kingdom
China
Cnot8 (NM_026949) Mouse Untagged Clone
CAT＃: MC210852
Cnot8 (untagged) - Mouse CCR4-NOT transcription complex, subunit 8 (Cnot8), (10ug)
CNY 3,990.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 1500015I04Rik; 1810022F04Rik; AA536816; AU015770; AU043059 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC210852 representing NM_026949
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCCTGCGGCACTTGTAGAAAACAGTCAGGTCATCTGTGAGGTGTGGGCCAGCAATCTTGAGGAAGAGA TGCGGAAGATCCGTGAGATTGTCCTCAGCTACAGCTATATCGCTATGGACACAGAGTTCCCAGGTGTTGT TGTACGGCCGATCGGTGAATTTCGAAGCTCCATAGATTACCAGTATCAGCTTCTGCGGTGCAATGTTGAT CTTCTTAAAATCATCCAGCTGGGCCTTACGTTCACCAATGAGAAGGGGGAGTACCCGTCTGGAATCAACA CATGGCAGTTCAACTTCAAGTTCAACCTGACAGAGGATATGTACTCCCAGGATTCCATAGATCTGCTTGC AAACTCAGGGCTGCAGTTCCAGAAACACGAGGAGGAAGGGATCGATACACTGCACTTTGCAGAGCTGCTT ATGACATCGGGAGTGGTTCTCTGTGACAACGTCAAGTGGCTTTCATTTCACAGTGGTTATGATTTTGGCT ACATGGTAAAGCTGCTAACAGACTCTCGCCTGCCGGAAGAAGAACACGAGTTCTTTCATATCCTGAATCT TTTCTTCCCGTCCATTTACGATGTGAAATACCTGATGAAGAGCTGCAAAAACCTGAAGGGAGGCCTTCAG GAGGTGGCTGATCAGTTGGATCTGCAGAGGATCGGAAGGCAGCATCAAGCAGGCTCAGACTCTCTGCTGA CGGGGATGGCTTTCTTCAGGATGAAAGAGCTATTCTTTGAGGACAGTATTGACGATGCCAAGTATTGTGG GCGCCTCTATGGCCTGGGCACAGGGGTGGCCCAGAAGCAGAATGAGGATGTGGACTGTGCCCAGGAGAAG ATGAGCATCTTGGCCATGATCAACAACATGCAGCAGTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_026949 |
| Insert Size | 879 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_026949.3, NP_081225.1 |
| RefSeq Size | 2035 bp |
| RefSeq ORF | 879 bp |
| Locus ID | 69125 |
| UniProt ID | Q9D8X5 |
| Gene Summary | Has 3'-5' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT7. Catalytic component of the CCR4-NOT complex which is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence of its influence on mRNA expression. Associates with members of the BTG family such as TOB1 and BTG2 and is required for their anti-proliferative activity.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG203998 | Cnot8 (tGFP-tagged) - Mouse CCR4-NOT transcription complex, subunit 8 (Cnot8) |
CNY 2,850.00 |
|
| MR203998 | Cnot8 (Myc-DDK-tagged) - Mouse CCR4-NOT transcription complex, subunit 8 (Cnot8) |
CNY 1,416.00 |
|
| MR203998L3 | Lenti ORF clone of Cnot8 (Myc-DDK-tagged) - Mouse CCR4-NOT transcription complex, subunit 8 (Cnot8) |
CNY 4,750.00 |
|
| MR203998L4 | Lenti ORF clone of Cnot8 (mGFP-tagged) - Mouse CCR4-NOT transcription complex, subunit 8 (Cnot8) |
CNY 4,750.00 |
