United States
Germany
Japan
United Kingdom
China
Homer2 (NM_001164087) Mouse Untagged Clone
CAT＃: MC209736
Homer2 (untagged) - Mouse homer homolog 2 (Drosophila) (Homer2), transcript variant 3, (10ug)
CNY 3,990.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 9330120H11Rik; AW539445; CPD; Vesl-2 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC209736 representing NM_001164087
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGACTTTCACCAAAACGTCACAGAAGTTCGGGCAGTGGGCTGACAGCAGAGCCAACACCGTGTTCGGTT TGGGATTCTCCTCCGAGCTGCAGCTCACGAAGTTTGCAGAGAAGTTCCAGGAGGTAAGAGAAGCTGCCAG GCTAGCCAGAGACAAGTCCCAGGAGAAAACCGAGACCTCCAGCAATCATTCCCAAGAATCTGGGTGTGAA ACCCCGTCTTCCACTCAGGCATCCAGCGTCAATGGCACAGACGACGAAAAGGCCTCTCACGCGAGCCCAG CCGACACTCACCTCAAGTCTGAGAATGACAAGCTGAAGATCGCGCTGACACAGAGTGCTGCCAATGTGAA GAAGTGGGAGATGGAGCTGCAGACCCTGCGGGAGAGCAACGCCCGGCTGACCACGGCACTGCAGGAGTCG GCGGCCAGCGTGGAGCAGTGGAAGCGGCAGTTCTCCATCTGCAGGGACGAGAATGACAGGCTCCGCAGCA AGATCGAGGAGCTGGAAGAACAGTGCAGCGAGATAAACAGGGAGAAGGAGAAGAACACACAGCTGAAGAG GAGGATCGAGGAGCTGGAGTCAGAGGTCCGAGACAAGGAGATGGAGTTGAAAGATCTCCGAAAACAGAGT GAAATCATACCTCAGCTCATGTCCGAGTGTGAATATGTCTCTGAGAAGTTAGAGGCGGCCGAAAGAGACA ATCAAAACTTGGAAGACAAAGTGCGGTCTCTAAAGACAGACATCGAGGAGAGTAAATACCGACAGCGCCA CCTGAAGGGGGAGCTGAAGAGCTTCCTTGAGGTGCTGGATGGAAAGATCGACGACCTCCATGACTTCCGT AGAGGACTCTCCAAGTTAGGCACAGATAACTAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001164087 |
| Insert Size | 873 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001164087.1, NP_001157559.1 |
| RefSeq Size | 10982 bp |
| RefSeq ORF | 873 bp |
| Locus ID | 26557 |
| UniProt ID | Q9QWW1 |
| Gene Summary | Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2 (By similarity). Isoforms can be differently regulated and may play an important role in maintaining the plasticity at glutamatergic synapses (By similarity) Required for normal hearing (PubMed:25816005). Negatively regulates T cell activation by inhibiting the calcineurin-NFAT pathway. Acts by competing with calcineurin/PPP3CA for NFAT protein binding, hence preventing NFAT activation by PPP3CA (By similarity).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (3) represents use of an alternate promoter and 5' UTR and uses a downstream start codon, compared to variant 1. The resulting isoform (3) has a shorter N-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG218531 | Homer2 (tGFP-tagged) - Mouse homer homolog 2 (Drosophila) (Homer2) transcript variant 3, (10ug) |
CNY 3,140.00 |
|
| MR218531 | Homer2 (Myc-DDK-tagged) - Mouse homer homolog 2 (Drosophila) (Homer2), transcript variant 3 |
CNY 2,850.00 |
|
| MR218531L3 | Lenti ORF clone of Homer2 (Myc-DDK-tagged) - Mouse homer homolog 2 (Drosophila) (Homer2), transcript variant 3 |
CNY 4,750.00 |
|
| MR218531L4 | Lenti ORF clone of Homer2 (mGFP-tagged) - Mouse homer homolog 2 (Drosophila) (Homer2), transcript variant 3 |
CNY 4,750.00 |
