Pip4k2a (NM_008845) Mouse Untagged Clone
CAT#: MC209168
Pip4k2a (untagged) - Mouse phosphatidylinositol-5-phosphate 4-kinase, type II, alpha (Pip4k2a), (10ug)
CNY 3,990.00
Product images
Specifications
Product Data | |
Type | Mouse Untagged Clone |
Tag | Tag Free |
Synonyms | AW742916; Pip5k2a |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>MC209168 representing NM_008845
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCGACCCCTGGCAACCTGGGGTCCTCCGTCCTGGCGAGCAAGACCAAGACGAAGAAGAAGCACTTCG TGGCTCAGAAAGTGAAGCTGTTCCGGGCCAGCGACCCGCTGCTCAGCGTGCTCATGTGGGGGGTCAACCA TTCGATCAATGAACTGAGCCACGTTCAAATCCCTGTCATGTTGATGCCTGATGACTTCAAAGCCTACTCA AAGATAAAGGTTGACAACCACCTTTTTAACAAGGAAAACATGCCGAGCCATTTCAAGTTTAAGGAATACT GCCCAATGGTCTTCCGGAATCTGCGGGAGAGGTTTGGAATCGACGACCAAGATTTCCAGAATTCCTTGAC CAGAAGTGCACCCCTTCCCAATGACTCCCAGGCTCGCAGCGGGGCTCGGTTTCACACGTCTTATGATAAA AGATACGTCATCAAGACCATTACCAGTGAGGACGTGGCAGAGATGCACAACATCCTGAAGAAGTACCACC AGTATATAGTGGAATGTCATGGGGTCACACTTCTTCCTCAGTTCTTGGGAATGTACCGGCTTAATGTCGA TGGAGTGGAAATATATGTGATTGTTACAAGGAATGTGTTCAGCCACCGGCTATCTGTATATAGGAAATAC GACTTAAAGGGCTCGACAGTGGCTAGAGAAGCTAGTGATAAAGAAAAGGCCAAAGAGCTGCCAACTTTAA AGGATAATGACTTCATCAATGAGGGCCAAAAGATCTATATTGATGACAACAACAAAAAGATATTCCTAGA AAAACTGAAAAAGGATGTCGAGTTCCTTGCACAGTTAAAACTCATGGACTACAGCCTCCTGGTGGGGATT CACGATGTGGAGCGAGCAGAGCAGGAGGAGGTGGAGTGTGAGGAGAACGATGGGGAAGAAGAAGGAGAGA GTGACAGCACCCACCCGATCGGGACGCCACCAGACAGTCCCGGAAATACACTCAACAGCTCACCACCCTT GGCTCCTGGAGAGTTTGATCCAAACATTGATGTTTATGCAATTAAATGCCATGAGAATGCGCCTAGAAAA GAGGTATACTTCATGGCGATTATTGACATCCTTACTCATTACGATGCAAAAAAGAAAGCTGCCCACGCTG CAAAAACTGTTAAACATGGCGCTGGAGCTGAGATCTCGACTGTGAACCCAGAGCAGTATTCCAAGCGCTT TTTGGACTTTATTGGGCACATCTTGTAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
Restriction Sites | SgfI-MluI |
ACCN | NM_008845 |
Insert Size | 1218 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_008845.4, NP_032871.3 |
RefSeq Size | 3471 bp |
RefSeq ORF | 1218 bp |
Locus ID | 18718 |
UniProt ID | O70172 |
Gene Summary | Catalyzes the phosphorylation of phosphatidylinositol 5-phosphate (PtdIns5P) on the fourth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). May exert its function by regulating the levels of PtdIns5P, which functions in the cytosol by increasing AKT activity and in the nucleus signals through ING2. May regulate the pool of cytosolic PtdIns5P in response to the activation of tyrosine phosphorylation. May negatively regulate insulin-stimulated glucose uptake by lowering the levels of PtdIns5P (By similarity). May be involved in thrombopoiesis and the terminal maturation of megakaryocytes and regulation of their size.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) encodes the longest isoform (1). |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MG206362 | Pip4k2a (tGFP-tagged) - Mouse phosphatidylinositol-4-phosphate 5-kinase, type II, alpha (Pip5k2a) |
CNY 7,088.00 |
|
MR206362 | Pip4k2a (Myc-DDK-tagged) - Mouse phosphatidylinositol-5-phosphate 4-kinase, type II, alpha (Pip4k2a) |
CNY 5,488.00 |
|
MR206362L3 | Lenti ORF clone of Pip4k2a (Myc-DDK-tagged) - Mouse phosphatidylinositol-5-phosphate 4-kinase, type II, alpha (Pip4k2a) |
CNY 5,230.00 |
|
MR206362L4 | Lenti ORF clone of Pip4k2a (mGFP-tagged) - Mouse phosphatidylinositol-5-phosphate 4-kinase, type II, alpha (Pip4k2a) |
CNY 5,230.00 |
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