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Dbnl (NM_001146309) Mouse Untagged Clone
CAT＃: MC208364
Dbnl (untagged) - Mouse drebrin-like (Dbnl), transcript variant 3, (10ug)
CNY 3,990.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | Abp1; mAbp1; SH3P7 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC208364 representing NM_001146309
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCGGTGAACCTGAGCCGGAACGGGCCGGCGCTGCAGGAGGCCTACGTGCGCGTAGTCACCGAGAAAT CCCCGACCGACTGGGCTCTTTTTACCTATGAAGGCAACAGCAATGACATCCGTGTGGCTGGCACAGGAGA GGGAGGCCTGGAGGAGCTGGTGGAAGAGCTCAACAGCGGGAAGGTGATGTACGCCTTCTGCAGGGTGAAG GACCCCAACTCCGGCCTGCCCAAGTTTGTCCTCATCAACTGGACAGGAGAGGGTGTGAATGATGTGCGGA AAGGAGCATGTGCCAACCACGTCAGCACCATGGCCAACTTCCTGAAGGGTGCCCACGTGACCATCAATGC CCGGGCCGAGGAGGATGTGGAGCCTGAGTGCATCATGGAGAAGGTTGCCAAGGCCTCTGGGGCCAACTAC AGCTTCCATAAGGAAAGCACCTCCTTCCAGGATGTAGGGCCGCAGGCCCCAGTGGGCTCTGTGTACCAGA AGACCAATGCCATATCTGAGATCAAGAGAGTCGGCAAGGATAACTTCTGGGCCAAAGCTGAGAAGGAAGA AGAGAACCGCCGCCTGGAGGAGAAGCGGCGTGCCGAAGAGGAGCGGCAGCGGTTGGAGGAGGAGCGACGA GAGCGGGAGCTGCAGGAGGCTGCCCGACGTGAGCAGCGCTACCAGGAACAGCACAGATCAGCTGGAGCCC CGAGGACAGGTGAGCCAGAGCAGGAAGCCGTTTCAAGGACCAGACAGGAGTGGGAGTCTGCTGGGCAGCA GGCCCCACACCCACGAGAGATTTTCAAGCAGAAGGAAAGGGCAATGTCCACCACCTCTGTCACCAGCTCG CAGCCGGGCAAGCTGAGGAGCCCCTTCCTGCAGAAGCAACTCACTCAACCAGAAACCTCCTACGGCCGAG AGCCCACAGCTCCTGTCTCCCGGCCTGCAGCAGGTGTCTGTGAGGAGCCAGCGCCTAGCACTCTGTCTTC TGCCCAGACAGAAGAAGAACCTACATATGAAGTACCCCCAGAGCAGGACACCCTCTATGAGGAACCACCA CTGGTACAGCAGCAAGGGGCTGGCTCCGAACACATTGACAACTACATGCAGAGCCAGGGCTTCAGTGGAC AAGGGCTGTGCGCCCGGGCCTTGTATGACTACCAGGCAGCTGATGACACCGAGATCTCCTTTGACCCTGA GAACCTAATCACAGGCATCGAGGTGATTGACGAAGGCTGGTGGCGAGGCTATGGGCCTGACGGCCACTTT GGCATGTTTCCTGCCAACTACGTGGAGCTCATAGAGTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001146309 |
| Insert Size | 1299 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001146309.1, NP_001139781.1 |
| RefSeq Size | 2357 bp |
| RefSeq ORF | 1299 bp |
| Locus ID | 13169 |
| UniProt ID | Q62418 |
| Gene Summary | Adapter protein that binds F-actin and DNM1, and thereby plays a role in receptor-mediated endocytosis. Plays a role in the reorganization of the actin cytoskeleton, formation of cell projections, such as neurites, in neuron morphogenesis and synapse formation via its interaction with WASL and COBL. Does not bind G-actin and promote actin polymerization by itself. Required for the formation of organized podosome rosettes. May act as a common effector of antigen receptor-signaling pathways in leukocytes. Acts as a key component of the immunological synapse that regulates T-cell activation by bridging TCRs and the actin cytoskeleton to gene activation and endocytic processes.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (3) uses a different splice site in its 3' coding region, compared to variant 1. The resulting protein (isoform 2) is shorter when it is compared to isoform 1. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG223599 | Dbnl (tGFP-tagged) - Mouse drebrin-like (Dbnl) transcript variant 3, (10ug) |
CNY 4,750.00 |
|
| MR223599 | Dbnl (Myc-DDK-tagged) - Mouse drebrin-like (Dbnl), transcript variant 3 |
CNY 4,280.00 |
|
| MR223599L3 | Lenti ORF clone of Dbnl (Myc-DDK-tagged) - Mouse drebrin-like (Dbnl), transcript variant 3 |
CNY 6,180.00 |
|
| MR223599L4 | Lenti ORF clone of Dbnl (mGFP-tagged) - Mouse drebrin-like (Dbnl), transcript variant 3 |
CNY 6,180.00 |
