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Terf2ip (NM_020584) Mouse Untagged Clone
CAT＃: MC207538
Terf2ip (untagged) - Mouse telomeric repeat binding factor 2, interacting protein (Terf2ip), (10ug)
CNY 3,990.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | Rap1 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC207538 representing NM_020584
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCGGAGGCGATGGATCTGGGTAAAGACCCCAATGGGCCCACTCACTCCTCCACTCTGTTCGTGAGAG AAGACGGCAGCGCCATGTCGTTTTACGTGCGGCCCAGCTCGGCCAAGCGCCGGCTGTCGACGCTCATCCT GCACGGCGGCGGCACCGTGTGTCGGGTGCAGGAACCCGGAGCCGTGCTTCTCGCCCAGCCCGGGGAGGCG CTGGCCGAGGCTTCGGGCGACTTCATCTCCACGCAGTACATCCTAGACTGCGTGGATCGCAACGAGAAGC TGGACCTGGAGGCCTATCGGCTGGGCCTGACGGAGCAGGCGTCCGATCCGAAGCCCGGGGCTTCCACCGA GGGCTCCACGGAACCGGAGCCGCAGCCCCTGACCGGGCGCATCGCCTACACCGACGCGGAAGATGTGGCC ATCCTGACCTACGTGAAGGAGAACGCCCGTTCGCCCAGCTCGGTCACAGGCAATGCCTTGTGGAAAGCGA TGGAGAAGAGCTCGCTCACGCAGCACTCCTGGCAGTCGCTCAAGGACCGCTACCTCAAGCACCTACGGGG TCAGGAGCACAAGTACCTGCTCGGGAACGCCCCGGTCAGCCCGTCCTCCCAGAAGCTCAAACGGAAGGCG GAGCAGGACCCCGAGGCCGCGGATAGCGGAGAGCCACAGAACAAGAGAGCGCCAGACTTGCCTGAGGAGG AGTGTGTGAAAGGAGAGATCAAGGAGAATGGAGAGGCAGACAACAAGCTGTTTGAGGAAGCCGCTCCGGA GTTCGGAGAAGCCGTGGTGGATGAGAGCCCTGACTTTGAAATACATATAACGATGTGTGATGGTGATCCA CCCACACCCGAGGAAGACTCAGAAACACAGCCAGACGAGGAGGAAGAAGAACCAAAAGTTTCTACGCAAG AAGTGGGAACTGCCATTAAGGTGATCCGGCAGCTAATGGAGAAGTTCAACTTGGATCTATCAACAGTTAC ACAGGCCTTGCTGAAGAACAGTGGTGAGCTGGAGGCCACGTCCTCCTTCTTAGAGTCGGGGCGGAGACCC GACGGTTATCCCATTTGGTGCAGACAAGATGACTTAGATTTGCAGAAGGACGATGACGACACGAAAAATG CACTGGTCAAAAAGTTTGGAGCTCAGAACGTTGCTCGGAGGATTGAATTCCGAAAGAAATAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_020584 |
| Insert Size | 1182 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_020584.2, NP_065609.2 |
| RefSeq Size | 3599 bp |
| RefSeq ORF | 1182 bp |
| Locus ID | 57321 |
| UniProt ID | Q91VL8 |
| Gene Summary | Acts both as a regulator of telomere function and as a transcription regulator. Involved in the regulation of telomere length and protection as a component of the shelterin complex (telosome). In contrast to other components of the shelterin complex, it is dispensible for telomere capping and does not participate in the protection of telomeres against non-homologous end-joining (NHEJ)-mediated repair. Instead, it is required to negatively regulate telomere recombination and is essential for repressing homology-directed repair (HDR), which can affect telomere length. Does not bind DNA directly: recruited to telomeric double-stranded 5'-TTAGGG-3' repeats via its interaction with TERF2. Independently of its function in telomeres, also acts as a transcription regulator: recruited to extratelomeric 5'-TTAGGG-3' sites via its association with TERF2 or other factors, and regulates gene expression. When cytoplasmic, associates with the I-kappa-B-kinase (IKK) complex and acts as a regulator of the NF-kappa-B signaling by promoting IKK-mediated phosphorylation of RELA/p65, leading to activate expression of NF-kappa-B target genes.[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MR206137 | Terf2ip (Myc-DDK-tagged) - Mouse telomeric repeat binding factor 2, interacting protein (Terf2ip) |
CNY 5,488.00 |
|
| MR206137L3 | Lenti ORF clone of Terf2ip (Myc-DDK-tagged) - Mouse telomeric repeat binding factor 2, interacting protein (Terf2ip) |
CNY 5,890.00 |
|
| MR206137L4 | Lenti ORF clone of Terf2ip (mGFP-tagged) - Mouse telomeric repeat binding factor 2, interacting protein (Terf2ip) |
CNY 5,890.00 |
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