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Mme (BC034092) Mouse Untagged Clone
CAT＃: MC206432
Mme (untagged) - Mouse membrane metallo endopeptidase (cDNA clone MGC:31469 IMAGE:4483558), (10ug)
CNY 8,248.00
货期*
现货
规格
| Cited in 1 publication. |
Product images
经常一起买 (2)
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | NEP, CD10, CALLA, 6030454K05Rik |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC034092
GTGACCGAGAGCAGCGCTGCCAAATTGCACCGGGGTTCATTTGGGGGCTGGGAATTGGCCATTCCGCTGT ACAGACACTGTTTTTATTTTAAAAAACAAGATTTTAGGTGATGGGAAGATCAGAAAGTCAGATGGATATA ACTGATATCAATGCTCCAAAGCCAAAGAAGAAACAGCGATGGACTCCCCTGGAGATCAGCCTCTCTGTGC TTGTCTTGCTCCTGACTATCATAGCGGTGACAATGATCGCTCTCTATGCAACCTATGATGATGGCATTTG CAAATCATCAGACTGCATAAAATCAGCTGCTCGACTGATTCAGAATATGGATGCCTCTGTTGAGCCATGT ACAGACTTCTTCAAGTATGCTTGTGGAGGCTGGTTGAAACGCAACGTCATTCCCGAGACCAGTTCCCGAT ACAGTAATTTTGACATTTTAAGAGATGAGCTAGAAGTCATTTTGAAAGATGTCCTTCAAGAACCCAAAAC TGAAGACATAGTAGCAGTGCAGAAAGCAAAAACCTTGTACAGATCGTGTATAAATGAGTCTGCTATTGAT AGCAGAGGCGGACAACCTCTACTCAAACTGTTACCAGATATATATGGGTGGCCAGTAGCATCAGATAACT GGGATCAAACATATGGCACTTCTTGGACAGCTGAGAAATCCATTGCACAACTGAATTCTAAATATGGGAA AAAGGTCCTCATTAATTTTTTTGTTGGCACTGATGATAAGAATTCTACCCAGCATATAATTCATTTTGAC CAGCCTCGACTTGGCCTCCCTTCCAGAGACTACTATGAGTGCACTGGAATATATAAAGAGGCTTGCACAG CATATGTGGATTTTATGATTTCTGTGGCCAGACTGATTCGTCAGGAACAAAGTTTGCCTATTGATGAAAA CCAGCTCTCTTTGGAAATGAATAAAGTTATGGAATTGGAAAAAGAAATTGCCAATGCTACAACTAAACCA GAAGACCGAAATGACCCAATGCTGCTTTATAACAAAATGACATTGGCCAAGCTGCAGAACAACTTTTCCC TGGAGGTCAATGGGAAGTCATTCAGCTGGTCAAATTTCACAAATGAAATCATGTCAACTGTGAATATTAA TATTCAAAATGAGGAAGAAGTTGTTGTCTATGCTCCAGAATATTTAACCAAACTTAAGCCTATTCTTACC AAATATTCTCCCAGAGATCTTCAAAATTTAATGTCCTGGAGGTTCATAATGGATCTTGTAAGCAGCCTCA GCCGAAACTACAAGGAGTCCAGAAATGCTTTCCGCAAGGCCCTTTATGGGACTACATCAGAAACTGCAAC ATGGAGACGGTGTGCTAACTACGTCAATGGGAATATGGAGAATGCTGTGGGGAGGCTTTATGTGGAAGCG GCTTTTGCTGGAGAGAGCAAGCACGTGGTTGAAGACTTGATTGCACAAATCCGGGAAGTTTTTATTCAGA CTTTGGATGACCTTACTTGGATGGATGCTGAGACAAAAAAGAAAGCTGAAGAAAAGGCCTTGGCAATTAA AGAAAGGATTGGCTATCCTGATGACATCATTTCCAATGAGAACAAACTGAATAATGAGTATCTTGAGTTG AACTACAGGGAAGATGAATACTTTGAGAACATAATTCAAAATTTGAAATTCAGCCAAAGCAAGCAGCTAA AGAAGCTCCGAGAAAAAGTGGACAAAGATGAGTGGATAAGTGGAGCAGCTGTAGTCAATGCATTTTATTC CTCAGGCCGAAATCAGATAGTCTTCCCCGCTGGCATTTTGCAGCCCCCATTCTTCAGTGCTCAGCAATCC AACTCATTGAACTATGGGGGCATCGGCATGGTCATTGGACATGAAATCACACATGGATTTGATGACAATG GAAGAAATTTCAATAAAGATGGAGACCTCGTTGACTGGTGGACGCAGCAGTCGGCAAATAATTTTAAAGA CCAATCCCAGTGTATGGTATACCAGTATGGAAACTTTTCCTGGGACCTAGCAGGTGGACAGCATCTCAAT GGAATTAATACACTAGGAGAAAACATTGCTGATAATGGAGGTATTGGCCAAGCATACAGAGCCTATCAGA ATTATGTTAAAAAGAATGGTGAAGAAAAATTACTCCCTGGACTTGACCTCAATCACAAACAACTATTTTT CCTGAACTTTGCCCAGGTGTGGTGTGGGACCTACCGGCCAGAGTATGCAGTCAATTCTATTAAAACAGAT GTACACAGTCCTGGAAATTTCAGGATCATTGGGACTTTGCAGAACTCTGCCGAGTTTGCAGATGCCTTTC ATTGCCGCAAGAATTCATACATGAATCCAGAAAGGAAATGTCGGGTTTGGTGATCTTCACAAGATACTGA ACATCCACGGCAAGATTTGCCAAAGCCACGGAAACAGGAACTCTTCCCTCAGAGAAACTGGGCCCCGGAA GTTTCTTCAGCTTCCTGGGGGGCAATTCACAGAGACGAGCATGAGCTAACATAAATGAAATTAGATTATT AAATCTGCTGTGAATGAAAGGGGAGGGAGCCTACGATCTAGCAAATCAATCACTTCACTGTGTAAATAAT GATTACTTTCCAACGGTAGTACTACCGTTCACTTCTGTTTCTCACACAGACTGCAGCTTTCATGTTGTCT GTAGAGAGGAGTGTTAACACTTAAAGCAGACTATGACTTCTGATCAAAAAGAGGACGATGCTCAGTACAG CAGGGCACCAAAGCACAGATTTGCCCCTCAGCACTCACTTTTGTTTGCAACATTCATGCTCCTTCCAAAC TCTCCCAAAGAACTCCCATACAGACTGTGGCCTTCAGGCTCGTGCAGTTTTGAACTCATTTTACCATACA TAAGTTATTCATTCATTCCACATCAATTTAGTTTGAACACTCTTAGAGCTTAAACTAGAGTATCTGAAAC GGTTCCCCTATTTCACCCACTTTAGTGATGTTGAGATTCTTGAACCCCCCTGCAGATCTTTGAGCAATTT CTTGCTCTTGCTGCCCCTCAGACTCAGTCTTTTAAAGGATTTGTAGTAATGTATAAAGAATAATTCTATA TTTAATTATTAACTACATTTATGACTGAATAAACCATTGCTATAGGTAATCATTGAATATTGAAGTTATA TGGCCAAGATAGTTTTGAAGATCTGTAACATGATATACAGACAAAAATTTGAGACTCTTTAAATCTGTAA ATCATATTGATGAAAAGCTTTAAGTACAAACTCTGGGGGTGAGCATTACCATTGGACGGGTGTCTTGAGA TACATAATAGTTGTGGTTTACAAACAGCATTTTCAAGATTAAGTCTGTCCCTAGTGGCTAAGAAAGGGTC TAACTGTATCTGTGTTGCTCCATGAATGCTTAGCCTTCAGGTTTGTCATCAAATGAAAATATTTTGATAA TAAATTGACGTTGTGAGCCCCTTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | RsrII-NotI |
| ACCN | BC034092 |
| Insert Size | 2253 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC034092, AAH34092 |
| RefSeq Size | 3623 bp |
| RefSeq ORF | 2253 bp |
| Locus ID | 17380 |
| Gene Summary | Thermolysin-like specificity, but is almost confined on acting on polypeptides of up to 30 amino acids. Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF) (By similarity). Displays UV-inducible elastase activity toward skin preelastic and elastic fibers (PubMed:20876573).[UniProtKB/Swiss-Prot Function] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Messenger RNA-based therapeutics for brain diseases: An animal study for augmenting clearance of beta-amyloid by intracerebral administration of neprilysin mRNA loaded in polyplex nanomicelles
,Lin, CY;Perche, F;Ikegami, M;Uchida, S;Kataoka, K;Itaka, K;,
J Control Release
,PubMed ID 27282413
[Mme]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG210456 | Mme (tGFP-tagged) - Mouse membrane metallo endopeptidase (cDNA clone MGC:31469 IMAGE:4483558) |
CNY 9,840.00 |
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