Rcn3 (BC025602) Mouse Untagged Clone
CAT#: MC206293
Rcn3 (untagged) - Mouse reticulocalbin 3, EF-hand calcium binding domain (cDNA clone MGC:36253 IMAGE:5250505), (10ug)
CNY 2,400.00
货期*
现货
规格
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经常一起买 (3)
Specifications
Product Data | |
Type | Mouse Untagged Clone |
Tag | Tag Free |
Synonyms | 6030455P07Rik; D7Ertd671e; D530026G20Rik; RLP49 |
Vector | PCMV6-Kan/Neo |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>BC025602
CCACGCGTCCGCATCTTTGTGCGAAAGCAGAGCTCAGCGTAGGGAGCTAACTCAGGCCGGGTAACAGAGG AACCGATGATGTGGCGATGGTCGTTTCTGTTGCTTCTCTTACTGCTGAGGCACTGGGCCCTCGGGAAGCC ATCCCCTGATGCAGGACCTCATGGCCAGGATAGGGTCCATCATGGAACCCCCCTGAGCGAGGCCCCCCAC GATGACGCCCACGGGAATTTCCAGTACGACCATGAGGCGTTCCTGGGACGAGACGTGGCCAAGGAATTTG ACAAACTCAGCCCAGAGGAAAGCCAGGCCCGACTTGGGCGGATCGTAGACCGCATGGATCTTGCTGGGGA CAGCGACGGCTGGGTGTCCTTAGCTGAGCTCCGCGCGTGGATCGCGCACACACAGCAGCGGCACATCCGT GACTCGGTGAGCGCAGCCTGGCACACCTACGACACGGACCGCGACGGGCGCGTGGGTTGGGAGGAGTTGC GCAATGCCACCTATGGCCATTATGAGCCCGGAGAGGAGTTTCATGATGTGGAGGATGCCGAGACCTACAA GAAGATGCTGGCTCGGGATGAGCGGCGATTCCGGGTAGCCGACCAAGATGGCGACTCCATGGCTACTCGG GAAGAGCTGACGGCCTTTCTGCATCCGGAGGAGTTCCCTCACATGCGGGACATCGTGGTAGCAGAGACCC TGGAGGACCTTGACAAGAACAAAGATGGCTACGTGCAGGTGGAAGAGTATATCGCGGACCTGTACTCCGA GGAGCCTGGGGAGGAGGAACCTGCCTGGGTGCAGACAGAGCGGCAGCAGTTCCGAGAGTTCCGGGATCTG AACAAGGACGGGCAACTGGATGGCAGTGAAGTCGGTTACTGGGTGCTGCCTCCATCCCAGGACCAGCCCC TGGTGGAGGCCAACCACCTGCTGCATGAGAGCGACACGGACAAGGATGGCCGGCTGAGCAAAGCTGAGAT CTTGAGCAACTGGAACATGTTTGTGGGCAGCCAGGCCACCAACTACGGTGAGGACCTGACAAGGCACCAT GATGAGCTCTGATCCCCATGTCTCTCAGACTTCCGACCACATGACCACATGGGGGACAACCGCGGGGCCA CTGCAGCCAGCCCCGCCCCCAGGACACAGACTCAGCTCTGGTGTTCCTGGTTCTTGGGCCCTCAGTCACC TTCTCTCCCTGAGACCCCTGTCACCAACCCTGGGACCCCCCAACCTGCCCAGGATACTCAGGCACTCAAA GATAAGTGACACCCACTGATAGCATCCCAGCACTGACGCGGGGCCACATCCTGACCTAACCGCAATTTGA ACTCTGAATGTCAACAGCACAAGCTAACCTGTCCTGCCTAGGAGCAATAAAAGCTGTTGCTGGGGTCCCC TGCTCAAAAAAAAAAAAAAAA |
Restriction Sites | EcoRI-NotI |
ACCN | BC025602 |
Insert Size | 987 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | BC025602, AAH25602 |
RefSeq Size | 1421 bp |
RefSeq ORF | 987 bp |
Locus ID | 52377 |
Gene Summary | Probable molecular chaperone assisting protein biosynthesis and transport in the endoplasmic reticulum (PubMed:26252542). Required for the proper biosynthesis and transport of pulmonary surfactant-associated protein A/SP-A, pulmonary surfactant-associated protein D/SP-D and the lipid transporter ABCA3 (PubMed:26252542). By regulating both the proper expression and the degradation through the endoplasmic reticulum-associated protein degradation pathway of these proteins plays a crucial role in pulmonary surfactant homeostasis (PubMed:26252542). Has an anti-fibrotic activity by negatively regulating the secretion of type I and type III collagens (By similarity). This calcium-binding protein also transiently associates with immature PCSK6 and regulates its secretion (By similarity).[UniProtKB/Swiss-Prot Function] |
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