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Ncoa1 (BC068177) Mouse Untagged Clone
CAT＃: MC206201
Ncoa1 (untagged) - Mouse nuclear receptor coactivator 1 (cDNA clone MGC:92937 IMAGE:30628581), (10ug)
CNY 9,624.00
货期*
现货
规格
| Cited in 1 publication. |
Product images
经常一起买 (3)
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | SRC1, SRC-1 |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC068177
CAGGTGTGAAGTTCATCAACATGAGTGGCCTTGGGGACAGTTCATCAGACCCTGCAAACCCAGACTCTCA TAAGAGAAAAGGATCGCCATGTGACACGCTGGCATCAAGTACTGAGAAGAGGCGCAGGGAGCAAGAAAAT AAGTATTTAGAAGAACTAGCTGAACTACTGTCTGCCAACATCAGTGACATTGACAGCTTGAGTGTAAAAC CAGATAAATGCAAGATTTTGAAGAAGACAGTAGATCAGATACAGCTAATGAAGAGAATGGAGCAAGAGAA ATCCACGACTGATGATGACGTGCAGAAGTCCGACATCTCCTCGAGCAGCCAAGGAGTGATAGAGAAGGAG TCGCTGGGCCCTCTTCTTCTGGAGGCTTTGGATGGATTTTTCTTTGTTGTGAACTGTGAAGGAAGAATTG TATTTGTATCAGAAAATGTGACCAGCTACTTGGGTTACAATCAGGAAGAATTAATGAATACCAGCGTCTA CAGCATACTGCATGTGGGAGATCATGCAGAATTTGTCAAGAATCTGCTACCAAAATCACTAGTAAATGGA GTTCCTTGGCCTCAAGAGGCAACACGCCGAAATAGCCATACATTTAACTGCAGGATGCTAATTCACCCTC CAGAGGACCCAGGTACTGAGAACCAAGAAGCTTGCCAGCGCTATGAAGTAATGCAGTGTTTCACAGTGTC ACAGCCAAAATCCATCCAAGAAGATGGTGAAGATTTCCAGTCATGTCTGATTTGTATTGCTCGACGATTA CCTCGGCCTCCAGCCATTACAGGTGTAGAATCCTTTATGACCAAGCAAGATACTACAGGCAAAATCATCT CTATTGACACTAGCTCCCTGAGGGCTGCTGGCAGGACTGGCTGGGAAGACCTAGTAAGGAAGTGCATCTA TGCTTTCTTCCAACCTCAGGGCAGAGAGCCATCTTACGCCCGGCAGCTGTTTCAAGAAGTGATGACTCGT GGCACTGCCTCCAGCCCATCCTATAGATTCATATTGAATGATGGGACAATGCTTAGCGCCCACACCAAGT GTAAACTTTGCTACCCTCAAAGTCCTGACATGCAGCCTTTCATCATGGGAATTCATATCATCGACAGGGA GCACAGTGGGCTTTCTCCTCAAGATGACAGTAATTCTGGAATGTCAATTCCCCGAATAAATCCCTCAGTC AATCCTGGTATCTCTCCAGCCCATGGTGTGACCCGTTCATCCACGTTGCCACCATCCAACAACAACATGG TCTCTGCCAGAGTAAACCGCCAACAGAGCTCAGACCTCAACAGCAGCAGCAGTCATACTAACTCTAGCAA CAACCAAGGGAACTTTGGATGTTCACCTGGAAATCAGATTGTAGCCAATGTTGCCTTAAACCAGGGACAG GCAGGTTCCCAGAGCAGCAATCCCTCTTTAAACCTCAATAATTCTCCTATGGAAGGTACAGGAATTGCCC TCTCACAGTTCATGTCTCCGAGGAGACAAGCTAATTCTGGCTTGGCAACAAGGGCCAGGATGTCAAACAA TTCATTTCCTCCAAATATTCCAACATTAAGCTCCCCAGTTGGCATTACTAGTGGTGCCTGTAATAATAAT AATCGATCCTATTCAAATATCCCAGTAACATCTTTACAAGGTATGAATGAAGGACCCAATAACTCTGTTG GCTTCTCTGCTGGGTCTCCAGTCCTTCGGCAGATGAGCTCACAGAATTCACCTAGCAGATTAAGTATGCA ACCAGCAAAGGCTGAGTCCAAAGACAGCAAAGAGATTGCATCCATTTTAAATGAAATGATTCAGTCCGAC AACAGCGACAACAGTGCTAACGAAGGCAAGCCTCTGGACTCAGGACTTCTGCATAACAATGACAGACTCT CAGAAGGAGACAGTAAATACTCTCAAACTAGTCACAAGCTAGTACAGCTATTGACTACGACCGCAGAGCA GCAGTTACGGCATGCCGACATAGACACAAGCTGCAAAGATGTACTGTCTTGCACTGGTACTTCCAGCTCT GCCTCCTCTAACCCCTCAGGAGGTACTTGTCCCTCTTCTCACAGCTCTCTGACTGAGCGGCATAAAATTC TGCACCGGCTTTTACAGGAGGGCAGCCCCTCAGACATCACCACTTTGTCTGTGGAACCCGAGAAGAAGGA CAGTGTGCCAGCCTCTACTGCTGTGTCAGTGTCTGGACAATCCCAGGGGAGTGCCAGCATAAAACTGGAA CTGGATGCTGCAAAGAAAAAAGAGTCAAAAGACCATCAGCTCCTACGCTACCTTTTAGACAAAGATGAGA AAGATTTAAGGTCCACTCCAAACCTGTGCCTGGATGACGTAAAGGTCAAAGTGGAGAAGAAAGAACAGAT GGATCCTTGTAACACAAACCCAACCCCAATGACCAAACCTGCTCCTGAGGAAGTTAAACTGGAGTCCCAG AGCCAGTTTACAGCTGACCTTGACCAGTTTGATCAGTTATTGCCCACCCTGGAGAAGGCAGCACAGTTGC CGAGCTTGTGCGAGACAGACAGGATGGATGGTGCGGTCACCGGTGTCAGCATCAAGGCGGAGGTCCTGCC AGCGTCACTCCAGCCCACCACTGCCAGAGCTGCCCCCAGGCTGAGCAGATTGCCTGAACTAGAATTAGAA GCGATCGATAACCAGTTTGGACAACCAGGAGCGGGGGATCAGATTCCATGGGCAAATAATACTTTGACAA CAATAAATCAGAATAAACCAGAAGACCAATGTATTAGCTCACAGCTGGATGAGCTCCTCTGTCCACCAAC AACAGTAGAAGGAAGAAACGATGAGAAGGCCCTTCTGGAACAACTGGTGTCTTTCCTCAGTGGCAAAGAT GAAACGGAGCTGGCTGAGCTAGACCGGGCACTGGGGATCGACAAGCTCGTCCAGGGAGGCGGATTAGATG TATTATCTGAGCGATTTCCACCACAGCAAGCAACACCACCTTTGATGATGGAAGACAGACCCACCCTCTA TTCCCAGCCATACTCATCTCCTTCTCCCACCGCTGGTCTCTCTGGCCCTTTCCAAGGCATGGTCCGGCAG AAGCCTTCACTGGGGGCTATGCCGGTTCAAGTAACACCTCCTCGAGGAACCTTTTCACCCAACATGGGCA TGCAGCCCCGGCAGACTCTCAATAGACCTCCAGCTGCACCCAACCAGCTTCGGCTGCAGCTGCAGCAGCG GCTACAGGGGCAGCAGCAGTTGATGCACCAAAACCGGCAAGCCATCTTGAACCAGTTTGCAGCAAATGCT CCTGTTGGCATGAACATGAGGTCAGGCATGCAGCAGCAGATCACACCTCAGCCACCCTTGAATGCTCAGA TGTTGGCCCAGCGCCAGCGGGAGTTGTACAGTCAGCAGCATCGACAGAGGCAAATTATACAGCAGCAGAG AGCCATGCTCATGAGGCACCAAAGTTTTGGGAACAACATCCCTCCTTCATCTGGACTCCCAGTTCAAATG GGGACTCCCCGTCTTCCTCAGGGTGCTCCCCAGCAGTTCCCCTACCCACCAAACTATGGTACAAACCCAG GAACCCCACCTGCCTCCACCAGCCCTTTCTCTCAACTGGCAGCAAACCCTGAGGCCTCCTTGGCCACCCG CAGCAGCATGGTGAACAGAGGCATGGCAGGGAACATGGGAGGACAGTTTGGCGCTGGCATCAGTCCTCAG ATGCAGCAGAATGTCTTCCAATATCCAGGACCAGGACTAGTTCCCCAAGGTGAGGCCACCTTTGCCCCAT CTCTAAGCCCTGGGAGCTCCATGGTGCCGATGCCAGTCCCTCCTCCTCAAAGCTCTCTGCTCCAGCAAAC TCCACCTACTTCTGGGTACCAGTCACCAGACATGAAGGCCTGGCAGCAAGGAACAATGGGAAACAACAAT GTGTTCAGTCAAGCTGTCCAGAGCCAGCCTGCACCTGCACAGCCAGGAGTGTACAACAACATGAGCATCA CCGTGTCCATGGCAGGTGGAAACGCAAACATTCAGAACATGAATCCAATGATGGGCCAGATGCAAATGAG CTCTCTGCAGATGCCAGGGATGAATACTGTGTGCTCTGAGCAGATGAATGATCCAGCACTGAGACACACA GGCCTCTACTGCAACCAGCTCTCGTCCACTGACCTTCTCAAAACAGACGCAGATGGAAACCAGGACAAGA AGACAGAAGAGTTCTTCTCTGTGGTGACTACAGACTAGAGGAGCTCTACAGGTGCAGCAGGTTCAGGTGT TTGCTGACGTCCAGTGTACAGTGAATCTGGTAGGCGGGGACCCTTACCTGAACCAGCCTGGTCCACTGGG AACTCAAAAGCCCACGTCAGGACCACAGACCCCCCAGGCCCAGCAGAAGAGCCTCCTTCAGCAGCTACTG ACTGAATAACCACTTTTAAAGGAATGTGAAATTTAAATAATAGACATGCAGAGTTATACAAATATATTAT ATATTTTTCTGAGATTTTTGATATCTCAATCTGCAGCCATTCTTCAGATCGTAGCATTTGGAGCAAAAAA AAAAAAAAAAAAAAA |
| Restriction Sites | AscI-NotI |
| ACCN | BC068177 |
| Insert Size | 4218 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC068177, AAH68177 |
| RefSeq Size | 4565 bp |
| RefSeq ORF | 4218 bp |
| Locus ID | 17977 |
| Gene Summary | Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Involved in the coactivation of different nuclear receptors, such as for steroids (PGR, GR and ER), retinoids (RXRs), thyroid hormone (TRs) and prostanoids (PPARs). Also involved in coactivation mediated by STAT3, STAT5A, STAT5B and STAT6 transcription factors. Displays histone acetyltransferase activity toward H3 and H4; the relevance of such activity remains however unclear. Plays a central role in creating multisubunit coactivator complexes that act via remodeling of chromatin, and possibly acts by participating in both chromatin remodeling and recruitment of general transcription factors. Required with NCOA2 to control energy balance between white and brown adipose tissues. Required for mediating steroid hormone response. Isoform 2 has a higher thyroid hormone-dependent transactivation activity than isoform 1 and isoform 3.[UniProtKB/Swiss-Prot Function] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
MicroRNA-223-3p inhibits human bladder cancer cell migration and invasion.
,null,
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine
,PubMed ID 28222670
[Ncoa1]
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