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Ulk1 (BC057121) Mouse Untagged Clone
CAT＃: MC206168
Ulk1 (untagged) - Mouse Unc-51 like kinase 1 (C. elegans) (cDNA clone MGC:63344 IMAGE:6834534), (10ug)
CNY 7,328.00
货期*
现货
规格
Product images
经常一起买 (3)
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | Unc51.1, mKIAA0722 |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC057121
CCGAGGCCCGGGTGCCGCGGATCTTTTGTTTCCCTGCGGGGCTCCGAGCCGCATCGTCAGTCAGGCCCGG ACTTGGAGCTGGAGTGTGTCAGAGCTGAGTCCCGAGTCGGACCGGGTCCCGACTGTCAGCGCCGGGAGGG TACCGAGGAGGACGCCGAGGGAGCGCGCCCCTCCGTCCGCCGGCCTGTGGGACTGGGACCCGGCTCAGGC CTGCCCGATGGGGCACGGGGCCCTGGCGATGAGCCCGCGCCTCCGTCCCCGCGTACGCGGCCCGCCGGCC TCCGCCTGAGCCCAGCGCACCCCGTAGCGCCGCCCCGGGGCCCGAGCCCGGGCTCGCGCCCCCGGCCCGC GCGCGCTATGGAGCCGGGCCGCGGCGGCGTCGAGACCGTGGGCAAGTTCGAGTTCTCTCGCAAGGACCTG ATTGGACACGGCGCCTTCGCGGTGGTCTTCAAGGGTCGACACCGCGAGAAGCACGACCTGGAGGTGGCCG TCAAATGCATTAACAAGAAGAACCTTGCCAAGTCCCAAACACTGCTGGGAAAGGAAATCAAAATCCTGAA GGAACTAAAGCACGAAAACATCGTGGCGCTGTATGACTTCCAGGAAATGGCTAATTCTGTCTACCTGGTC ATGGAGTATTGTAATGGTGGAGACCTGGCTGACTACCTGCACACTATGCGCACACTGAGTGAAGACACTG TCAGGCTTTTCCTACAGCAGATCGCTGGCGCCATGCGGCTGCTGCACAGCAAGGGCATCATCCACCGGGA CCTGAAGCCCCAAAACATCCTGCTGTCCAACCCTGGGGGCCGCCGGGCCAACCCCAGCAACATCCGAGTC AAGATTGCTGACTTTGGATTCGCTCGGTACCTCCAGAGCAACATGATGGCGGCCACACTCTGTGGTTCTC CTATGTACATGGCTCCTGAGGTCATTATGTCCCAGCACTACGATGGAAAGGCTGACCTGTGGAGCATTGG CACCATTGTCTACCAGTGTCTGACAGGGAAGGCCCCTTTTCAGGCCAGCAGCCCTCAGGATTTGCGCCTG TTTTATGAGAAGAACAAGACACTAGTTCCTGCCATCCCCCGGGAGACATCAGCTCCCCTGCGGCAGCTGC TCCTGGCTCTGTTGCAGCGGAACCACAAGGACCGCATGGACTTTGATGAATTTTTCCACCACCCTTTCTT GGATGCCAGCACCCCCATCAAGAAATCCCCACCTGTGCCTGTGCCCTCATATCCAAGCTCAGGGTCTGGC AGCAGCTCCAGCAGCAGCTCTGCCTCCCACCTGGCCTCTCCACCGTCCCTGGGGGAGATGCCACAGCTAC AGAAGACCCTTACCTCCCCAGCCGATGCTGCTGGCTTTCTTCAGGGCTCCCGGGACTCTGGTGGCAGCAG CAAAGACTCCTGTGACACAGATGACTTTGTCATGGTCCCAGCCCAGTTTCCAGGTGATCTAGTTGCTGAG GCAGCCAGTGCCAAGCCCCCACCTGATAGCCTGCTGTGTAGTGGGAGCTCATTGGTGGCCTCTGCTGGCC TAGAGAGCCACGGCCGTACCCCCTCTCCCTCTCCGACCTGCAGCAGCTCTCCCAGCCCCTCTGGCCGGCC TGGCCCCTTCTCCAGCAACAGGTACGGTGCCTCGGTCCCCATTCCTGTCCCCACTCAGGTGCACAATTAC CAGCGCATCGAGCAAAACCTGCAATCGCCCACTCAACAGCAGACAGCCAGGTCCTCTGCCATCCGAAGGT CAGGGAGCACCAGCCCCCTGGGCTTTGGCCGGGCCAGCCCATCACCCCCCTCCCACACCGATGGAGCCAT GCTGGCCAGGAAGCTGTCACTTGGAGGTGGCCGTCCCTACACACCTTCTCCCCAAGTGGGAACCATCCCA GAGCGACCCAGCTGGAGCAGAGTGCCCTCCCCACAAGGAGCTGATGTGCGGGTTGGCAGGTCACCACGAC CCGGTTCCTCTGTGCCTGAGCACTCTCCAAGAACCACTGGGCTGGGCTGCCGCCTGCACAGTGCCCCTAA CCTGTCCGACTTCCATGTTGTGCGTCCCAAGCTGCCTAAGCCCCCAACAGACCCACTGGGAGCCACCTTT AGCCCACCCCAGACCAGCGCACCCCAGCCATGCCCAGGGCTACAGTCTTGCCGGCCACTGCGTGGCTCAC CTAAGCTGCCTGACTTCCTACAGCGGAGTCCCCTACCCCCCATCCTAGGCTCTCCTACCAAGGCCGGGCC CTCCTTTGACTTCCCCAAAACCCCCAGCTCTCAGAATTTGCTGACCCTGTTGGCTAGGCAGGGGGTAGTA ATGACACCACCTCGGAACCGTACACTGCCTGACCTCTCCGAGGCCAGTCCTTTCCATGGCCAGCAGCTGG GCTCTGGCCTTCGGCCCGCTGAAGACACCCGGGGTCCCTTTGGACGGTCCTTCAGCACCAGCCGCATTAC GGACCTGCTGCTTAAGGCTGCATTTGGGACTCAGGCCTCTGACTCAGGCAGCACAGACAGCCTACAGGAG AAACCTATGGAGATTGCTCCCTCTGCTGGCTTTGGAGGGACTCTGCATCCAGGAGCTCGTGGTGGAGGGG CCAGCAGCCCAGCACCTGTGGTATTTACTGTAGGCTCCCCACCCAGTGGTGCCACCCCACCCCAGAGTAC CCGTACCAGAATGTTCTCAGTGGGCTCTTCCAGCTCCCTGGGCTCTACTGGCTCCTCCTCTGCCCGCCAC TTAGTGCCTGGGGCCTGTGGAGAGGCCCCGGAGCTTTCTGCCCCAGGCCACTGCTGTAGCCTTGCTGACC CCCTTGCTGCCAACTTGGAGGGGGCTGTGACCTTCGAGGCTCCTGACCTCCCAGAGGAGACCCTCATGGA GCAAGAGCACACGGAAACCCTACACAGTCTGCGCTTCACACTAGCGTTTGCACAGCAAGTTCTGGAGATT GCAGCCCTGAAGGGAAGTGCCAGTGAGGCCGCCGGTGGCCCTGAGTACCAGCTCCAGGAAAGTGTGGTGG CTGACCAGATCAGTCAGTTGAGCCGAGAGTGGGGCTTTGCAGAGCAACTGGTTCTGTACTTGAAGGTGGC TGAGCTGCTGTCCTCAGGCCTACAGACTGCCATTGACCAGATTCGAGCTGGCAAACTCTGCCTTTCATCT ACTGTGAAGCAGGTGGTACGCAGACTAAATGAGCTGTACAAGGCCAGCGTGGTATCCTGCCAGGGCCTCA GCTTGCGACTTCAGCGCTTCTTTCTGGACAAACAACGGCTGCTGGACGGGATCCATGGTGTCACTGCAGA GCGGCTCATCCTCAGCCATGCTGTGCAAATGGTACAATCAGCTGCCCTTGATGAGATGTTCCAGCACCGA GAGGGCTGTGTACCGAGATATCACAAAGCCCTGCTATTGCTGGAGGGGTTGCAGCACACTCTCACGGACC AGGCAGACATTGAGAACATTGCCAAATGCAAGCTGTGCATTGAGAGGAGACTCTCGGCCCTGCTGAGTGG TGTCTATGCCTGACTACCTGCTGCCAACCTGCAGGGTAGGGTCTGAGACCTGGCAGACTGTCCTCAACAC TGATCAGATCCGATGGTGCTGAGACTGCTGCCAGCCAACTCCAGCAGGGATGCTCCACAGTGGACCTGTG CAGACTGGTGCAACTCTTGCTTCCTAGACTGCCAGTCTCTGCTGGCAGGTAGACATCAGAGTGCCAGGGG TCCCTTGCCCACTGGGACAGGAGTTTCTGAACATATTCTTCCTAGCTGGCTCCCTGGCAAGCAGGTATGG TGCCGAGAAGTGGCACCTGCCACCTGAAGAGCCCATGGCAGCCCTGTGTCAGGCAAGGGCCTGAGACCGT TGCTGACTCCAAGCCAAAGCAAGCTTTTCCTCACAGTTCACTTGCCCCATTGCTTGTCCAAGAAAAAAGG GTATGGTCTTCTGGCCCCCTGTTCTCTCTAGGAACTTCTCCCTCTGAGACTACTTACCCAGCTTTGTAAG TCACCGGAGCACTTTATGCATACAGAGACTGGAGAACCTAGCCAGCAGTGCAGACTGCTGGGAACCTGCC TCCTGTTCCTGGCTTTCGTCCTCCAAGACGCTGTATAGATGCAGACCACATCTTTGTGTATAAAAAGCCC AGTGTTCACCTCCTCCTGTGTCTGGTCTTTGGAGGAAAGCAACAGGCTTGCCTCCTGAGGGAGAGATAGT CCTCACGTTTAAATGTTCATTAGGGACAGACAGTTCATTGTGTGAAGCACCACCCATGCTTGTTAAAACT CCTCAACTTCCACACTTTACTCCTAAGATGTGTCTCCACCCTCCCAACTCAGTTTTTGTTCATAAAAGGA AACTTCAGATGTTTAAGGATTGAAAGGGCGGAGGCAGGGCAGGCCAGGTATCACACTGGATGTTGTCCTT GTAGGAGACGGTGCCCGCTGTGTGGCTGAGGCTGTAGCATGTGCCAGAGCGAGTGTGCTGCTGGCTATCT CTATTAACTTTCCCTGGAAGGGCGGCAGAAAAGGCAGTGCCCAGGTGCCGTCCTCCCTGTGCAGTGGAGG TGTGGGTGAAGAATAACATATGCAAACATGTCCCCTGTGGAGCTTTCCTGTCAGTCTGGCTCCTGTGCTT GGTGGCCTTCAGGATCTGTGCTGAAGCTCGTCTTCCAGGCTCCAGGGTGGACACATGCTAATACCTTCCC AGCCTCCCTGACCTGCCAGTCCTTTGTCACGGCTCTGTTCATGCATACTTGAAAGTATCTGAGTGTCCAC AAGCTGATGTGGGGTTTCAGAGTTATAGGCCACACACACACACACACACACACGTTTTTCTTTGCAATAC TTGAAATATTGCCACTGTGCTTGGTTGTACAAGAGTTGTACAAGAAAGCAGATCTCTAAGACCAGTCTCT TCCTTAGTCACCCTATGACCTCCCTTGCATGTAACATGTTGTATTTATTGCTTTGTGGCCAACTGGAACC CAGAGCCACCAGGGAGGCTAGTGCAGGGATTCCTGACCCACCACCTGGTTCCTGAAAGGCTCCTGGGTGG CTGTGTGTGTGTGTGGCTGGCTGTGTGTGGTATGAGCCAAACCTGCTCATGAAAGCAGTGCTCAGGCCTG TCAATTTTAAGATGAATTTTGTGAGTCTCCCCCTTTTGTGTTTCACTGTGTCATATCAGTTTAAGAAAAT AAAAATTGGAATTATTAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | AscI-NotI |
| ACCN | BC057121 |
| Insert Size | 3156 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC057121, AAH57121 |
| RefSeq Size | 5215 bp |
| RefSeq ORF | 3156 bp |
| Locus ID | 22241 |
| Gene Summary | Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of regulatory feedback loops in autophagy: acts both as a downstream effector and negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR. Activated via phosphorylation by AMPK and also acts as a regulator of AMPK by mediating phosphorylation of AMPK subunits PRKAA1, PRKAB2 and PRKAG1, leading to negatively regulate AMPK activity. May phosphorylate ATG13/KIAA0652 and RPTOR; however such data need additional evidences. Plays a role early in neuronal differentiation and is required for granule cell axon formation. May also phosphorylate SESN2 and SQSTM1 to regulate autophagy (PubMed:25040165).[UniProtKB/Swiss-Prot Function] |
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