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Neil3 (NM_146208) Mouse Untagged Clone
CAT＃: MC206012
Neil3 (untagged) - Mouse nei like 3 (E. coli) (Neil3), (10ug)
CNY 4,520.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | AI449477; BC034753; C85903 |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC024921
GCGGGCTACAGAGATGGTGGAAGGGCCAGGGTGTACACTGAATGGAGAGAAGATCCGGGCACGAGTGCTA CCGGGGCAGGCGGTGACTGGCGTGCGGGGGACAGCTCTGCAGAGCCTCCTGGGCCCTGCCATGTCCCCTG CCGCCTCCCCGGCTGATGTCGCTACCTCGGCTGCTCCAATGAATGCTAAGGATTCTGGCTGGAAACTCTT GAGACTGTTTAATGGATATGTTTACAGTGGCGTGGAAACCTTAGGGAAGGAGCTGTTTATGTACTTTGGC CACAGAGCTTTACGGATTCATTTCGGAATGAAAGGCTCCATCTTGATTAACCCACGGGAGGGTGAGAACA GAGGTGGGGCTTCTCCAGCCTTGGCGGTGCAGCTCACCAGAGACTTGATCTGCTTCTATGACTCTTCAGT AGAACTCAGAAATTCGGTGGAAAGCCAACAGAGAGTCAGAGAGATGGAAGAGTTGGATATATGTTCACCA AAGTTCAGTTTCTCAAGAGCAGAGAGTGAAGTGAAAAAGCAGGGAGATCGGATGCTGTGTGATGTGTTGC TGGATCAGAGGGTGTTGCCTGGCGTGGGCAACATCATCAAAAATGAAGCACTCTTTGACAGTGGTCTTCA TCCGGCTGTTAAGGTGTGTCAACTATCAGACAAACAGGCCCGTCACCTTGTGAAGATGACTCGGGATTTC AGCATTCTCTTCTACAGGTGCTGTAAAGCAGGATCTGCCATTTCTAAACACTGTAAGGTTTACAAGCGTC CTAACTGTGGTCAGTGCCACAGCAAAATTACTGTGTGTCGCTTTGGGGAGAACAGCAGGATGACATATTT CTGTCCTCACTGTCAGAAAGAAAACCCTCAACGTGTTCAAGTATGCCAGCTGCCAACAAGAAACACTGAA ATCAGCTGGACTCCTAGGGGAGAGGATTGCTTTACGGACTCAGTGGCTCGGAAGTCTGAAGAGCAGTGGT CCTGTGCGGTTTGTACTCTCATAAACAGACCCTCGGCTAAGGCCTGTGATGCTTGCTTGACCACAAGGCC TCTGGATTCAGTGCTCAAGAATAGAGAAAATTCCATTGCCTTCAACAACTTAGTGAAGTACCCTTGTAAT AACTTTGAGAACACACACACTGAAGTAAAGATCAACAGGAAAACTGCGTTTGGAAATACGACCCTTGTTT TGACTGATTTAAGCAATAAATCCAGTGCTTTGGCCAGAAAGAAAAGAGCAAACCACACAATAGATGGGGA ATCTCAAATGTTTCTCCCTACAGACATAGGTTTTAGTGATTCACAGCACCCCTCCAAAGAAGGAATAAAC TATATAACTCAACCATCCAATAAGGTAAACATATCACCTACAGTTTGTGCCCAGTCTAAATTATTTAGTT CAGCACATAAAAAATTCAAACCAGCTCACACTTCTGCAACAGAACTTAAAAGTTACAACTCTGGACTTTC TAACAGTGAACTCCAAACCAATAGGACACGTGGCCATCATTCCAAAAGTGATGGCAGCCCTCTGTGCAAG ATGCACCACCGCCGCTGTGTTCTCCGAGTTGTGAGGAAAGATGGAGAAAACAAGGGGAGGCAGTTTTATG CCTGTTCTCTGCCGAGAGGAGCACAGTGCGGATTTTTTGAATGGGCAGACCTGTCCTTCCCGTTCTGCAA ACATGGCAAGCGCTCCATTATGAAAACTGTGCTGAAGATTGGACCTAATAATGGGAAGAATTTTTTTGTA TGTCCTTTGGAGAAAGAAAAGCAGTGTAATTTTTTCCAGTGGGCCGAAAATGGACCAGGAATGGAAATTG TTCCAGGATGCTAATAGTTTTCTCTTTTTAAAGAATGCCCGTCTCATAAACTCATCAAACTCATAGCATT CAGTCCCCTTTGTTTAATAGAAAACTTATAGAACACCTGTTGTACATACACATTAAGAACCTGTAGTATT TGAGACATTTTTTTTCACTTAACTATGTGATCTTCACAGTTTTTGTTGTAATAATGAACACACTATTTCA CCAGAGGCACAGTCCATTCTCTTTGAAATGCATATTCAATATAGTTAATAATGATGTCAATAAAGTACTC TTAGAATGTTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | RsrII-NotI |
| ACCN | NM_146208 |
| Insert Size | 1821 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC024921, AAH24921 |
| RefSeq Size | 2191 bp |
| RefSeq ORF | 1821 bp |
| Locus ID | 234258 |
| UniProt ID | Q8K203 |
| Gene Summary | DNA glycosylase which prefers single-stranded DNA (ssDNA), or partially ssDNA structures such as bubble and fork structures, to double-stranded DNA (dsDNA). In vitro, displays strong glycosylase activity towards the hydantoin lesions spiroiminodihydantoin (Sp) and guanidinohydantoin (Gh) in both ssDNA and dsDNA; also recognizes FapyA, FapyG, 5-OHU, 5-OHC, 5-OHMH, Tg and 8-oxoA lesions in ssDNA. No activity on 8-oxoG detected. Also shows weak DNA-(apurinic or apyrimidinic site) lyase activity. In vivo, appears to be the primary enzyme involved in removing Sp and Gh from ssDNA in neonatal tissues. Seems to be an important facilitator of cell proliferation in certain populations, for example neural stem/progenitor cells and tumor cells, suggesting a role in replication-associated DNA repair.[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG209359 | Neil3 (tGFP-tagged) - Mouse nei like 3 (E. coli) (Neil3) |
CNY 5,890.00 |
|
| MR209359 | Neil3 (Myc-DDK-tagged) - Mouse nei like 3 (E. coli) (Neil3) |
CNY 4,520.00 |
|
| MR209359L3 | Lenti ORF clone of Neil3 (Myc-DDK-tagged) - Mouse nei like 3 (E. coli) (Neil3) |
CNY 7,220.00 |
|
| MR209359L4 | Lenti ORF clone of Neil3 (mGFP-tagged) - Mouse nei like 3 (E. coli) (Neil3) |
CNY 7,220.00 |
