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Gna13 (NM_010303) Mouse Untagged Clone
CAT＃: MC205559
Gna13 (untagged) - Mouse guanine nucleotide binding protein, alpha 13 (Gna13), (10ug)
CNY 3,656.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | AU024132; AU043124; Galpha13 |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC057665
CGCAGGGGCCCGCCGAGGCGGCGGCGGCGGCAAGATGGCGGACTTCCTGCCGTCGCGCTCCGTGCTGTCC GTGTGCTTCCCGGGCTGCGTGCTGACGAACGGCGAGGCCGAGCAGCAGCGCAAGTCCAAGGAGATCGACA AATGCCTGTCGCGGGAGAAGACCTACGTGAAGCGGCTGGTGAAGATCCCGCTGCTGGGCGCGGGCGAGAG CGGCAAGTCCACCTTCCTGAAGCAGATGCGGATCATCCACGGCCAGGACTTCGACCAGCGCGCGCGCGAG GAGTTCCGCCCCACCATCTACAGCAACGTGATCAAAGGTATGAGGGTGCTGGTAGATGCCCGAGAGAAGC TTCATATTCCCTGGGGAGATAACAAAAACCAGCTCCATGGAGACAAGTTGATGGCATTTGATACCCGCGC CCCCATGGCTGCCCAGGGGATGGTGGAGACTCGAGTGTTCCTGCAGTATCTTCCTGCTATCAGAGCCTTA TGGGAGGACAGTGGTATACAGAATGCCTACGATCGGCGCCGGGAATTCCAGCTGGGTGAGTCTGTAAAGT ATTTCTTGGATAACTTGGATAAACTTGGAGTACCGGATTACATTCCATCACAGCAAGATATCCTGCTTGC CAGAAGGCCCACCAAAGGCATCCATGAGTACGACTTTGAAATTAAAAATGTTCCTTTCAAAATGGTTGAT GTAGGTGGCCAGAGATCAGAACGGAAACGCTGGTTTGAATGCTTTGACAGTGTGACGTCGATACTTTTCC TTGTCTCTTCAAGTGAATTTGACCAGGTGCTTATGGAGGACCGCCAGACCAATCGCCTTACAGAATCTCT GAACATTTTTGAAACAATTGTCAACAATCGGGTTTTCAGCAACGTCTCCATAATCCTCTTCTTAAACAAG ACAGACTTGCTCGAGGAGAAAGTGCAAGTTGTTAGCATCAAAGACTATTTCCTAGAATTTGAAGGGGACC CCCACTGCTTAAGAGACGTCCAAAAGTTTCTGGTGGAATGCTTCCGGGGGAAACGCCGGGACCAGCAGCA GAGGCCGTTGTACCACCACTTCACCACCGCGATCAACACAGAGAACATCCGCCTCGTGTTCCGGGACGTG AAGGACACGATCCTTCATGACAACCTGAAGCAGCTCATGCTGCAGTGATGACAAGACTGGCTGTTTTAAT ACCTTGTTGTGATTTTGATTGTTTTCTGTTTGTCTTGTTTTTCTCTTTAAATGGCAGTTTACAACAGCAG TTAGAAGAATCTCAGTTGTGTGTGTCTAACTTCTTGGAGAACTTAGTTCATCTGTGGCCTTTAGTTTGTG GCTGACAGCTGCTGAATTAACCCATTGCCAATATCTGCTAGAATTTGGGCTTTGATTGGTTTCACTGTGG CTTACCTTCAAGTCCAATTATAACTTCCTGGCAACCTTACACTAGGTGTTTTTCAGGCCTTGAATTCTCA TAACTGTCCTGCAGTTCTAAGAATAGGCAGTATCTTTAAGAACTTGTAGGGATGAGAGTATGAAAATTCA GCTCTAAAGAGAGAGTGCCTTACCCAGCAATGACATGCCTCGCTATGTGAGCCCTGGTCTGGAAGGGCTG TTAGAGAAAAGTTTTAGGGAGGAGTCTCGGCCCACAGAGGCTTGGCCCCCTACACACACAGCAGTAGTTT GTTTTTCTCAATCTCTTTACTTTCTGAAGGTAATGTCTTACTGCTTAAGTTTACAAGATGGATCTCAGCC TGATGCTGATGCGGTCACAAATGGTACATGTGCTATGTTGATCTGAGATGAGCAGTGACACGCAGTTTCC TTTGCCATACATGCTGTCACTAACTTAATGTGCCATGTTACAACATCTGGAGAGGGCAAGCACCCTGGTG ACGGACATCACCATAGCAGCCCCAGAGTGTGACTTTCTGGTCCTGTCTCCTTGGACTTTGTGCCTTGCTG GAGGGAACCACTGTTGGGTCTTCTTCCTTTTGCCCCACTGTCTCAACCTCAGCAGCTCTGAACTGTGGTG CTCTCGGGCTTCTCTTGTCCCCGAGAGCTTGGTGGGCAGCATTTCCCTGTGAACTGTTCAAAAAGGCATC CTTTCAGTACCCTGTCCCTGGTTAGTGTCTCTCTGTGACAGAGTTTGTATGTGTTGTGTGTGTCATCGTG TGTGAGACACAGCTTCATTGAGGTACATTCAAATGTCTTAAGGATGCATCTAAGGATAAGCAATTTTTTT TTTGGCCCATACTTAAGGAGGTTTGCCTTCACACACACACACACACACACACACACATACCATTGCTAAC TTAAACCATGCCCATGAGGTAGCTTGTGATAAAATACAGTGGCTGGTGTACAAAACCATTTGGCATGTTC CAACTGGCCTGGGAGTTTGTAGAACCTGAGCTTGTCCCTGCTGTCCCTGGAGAGCGCAAGAGGGCAGTGA AGCCTGTTTTATTGTGTGACTATTCTCAGGCAAGAAATTGCGCCCTGAAAGACTGGCTGACTATGAGGCC CAAAAGCAGTGGCTTTCTTCTTTTCTTGCTGGAGGGTGCCAGAGCTGGGCCCTAGTGTATGTATACTTGA GAGACCTGACTTGTCCTGGATTTGAGCTTTCACTGTCATTCTGGTTATAAAGTCCAGTGCTTTCTTGCCT TGGTAATATCATGAGCTTAAGACATGTATGTCAGTATCACAGTGCAGGTGTTGTTAGCATAATTCACCAT AATTCATGGTTCTACATCTGGTCCTTTTTCTGTCAAAAAAAAAAAAAAA |
| Restriction Sites | RsrII-NotI |
| ACCN | NM_010303 |
| Insert Size | 1134 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC057665, AAH57665 |
| RefSeq Size | 2779 bp |
| RefSeq ORF | 1134 bp |
| Locus ID | 14674 |
| UniProt ID | P27601 |
| Gene Summary | Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems (PubMed:21212405, PubMed:19151758, PubMed:16388592). Activates effector molecule RhoA by binding and activating RhoGEFs (ARHGEF1/p115RhoGEF, ARHGEF11/PDZ-RhoGEF and ARHGEF12/LARG) (PubMed:16388592). GNA13-dependent Rho signaling subsequently regulates transcription factor AP-1 (activating protein-1) (PubMed:19151758, PubMed:21212405). Promotes tumor cell invasion and metastasis by activating Rho/ROCK signaling pathway (By similarity). Inhibits CDH1-mediated cell adhesion in process independent from Rho activation (By similarity).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant 1 represents the longer transcript and encodes the longer isoform (1). |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG205863 | Gna13 (tGFP-tagged) - Mouse guanine nucleotide binding protein, alpha 13 (Gna13) |
CNY 5,256.00 |
|
| MR205863 | Gna13 (Myc-DDK-tagged) - Mouse guanine nucleotide binding protein, alpha 13 (Gna13) |
CNY 2,850.00 |
|
| MR205863L3 | Lenti ORF clone of Gna13 (Myc-DDK-tagged) - Mouse guanine nucleotide binding protein, alpha 13 (Gna13) |
CNY 4,750.00 |
|
| MR205863L4 | Lenti ORF clone of Gna13 (mGFP-tagged) - Mouse guanine nucleotide binding protein, alpha 13 (Gna13) |
CNY 4,750.00 |
