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Azin1 (NM_018745) Mouse Untagged Clone
CAT＃: MC205517
Azin1 (untagged) - Mouse antizyme inhibitor 1 (Azin1), transcript variant 2, (10ug)
CNY 3,656.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 1700085L02Rik; AZI; O; Oazi; Oazin |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC019412
GGCTCAACTCTCGCCGCGGTGTTTCCGTTTTTCTCTCTGGTTGTCTCCTGCTCTGCTCTTCTCATCCTTC TCGCTCTGCTGCTCTGCGGAGTGACGAGGCTGAATCCTCTCCCCACCCAGTTCGCGCCTTTCTTCTTTTT CTCGCGCCGCTCCATTTCTCCAGTTCGGCTGCCGCCGCCACTGCTGCTCAGCTGGTGTCGGTGCCGCGCG TTTCCCCCACGTCGTCCCCGCAGCCTATGGCCCAGGCCGCCTTGGGTATTTCTGCTCAAGGTAACCACAT CCCTCTTTAAAAATTCCGCCGAAAAAGAGAAGACGCTTTACCCGACTCTTTGGGCCGTTATCTCACGGCG AACTTTCTGACCGAGTATACAACTACCCAGAAGGCCTAGGAGAAGTGCTGTATAGAGAGCAGTTCGACTT CAACGCTGAGCCACCTTGGGAACCTAGCTGATGATAGGGGGTTCCATCTCCTAACTTGTCCATTTTGTTG CATATTCTAAGGACCCAGACATAGGCTTGGTGGCCCGTCTCTTGTTTTTCCTGGTTTATGACTTTCGGCT TTGTGGAATACGGCTGAGATGAAAGGATTTATTGACGATGCGAACTACTCCGTTGGCCTGTTGGATGAAG GAACAAACCTTGGAAATGTTATTGATAACTATGTTTATGAACATACCCTGACAGAGAAAAATGCATTTTT TGTGGGGGATCTTGGGAAGATCGTGAAGAAGCACAGTCAGTGGCAGACCGTGGTGGCTCAGATAAAGCCG TTTTACACGGTGAAGTGCAACTCCACTCCAGCCGTGCTTGAGATCTTGGCAGCTCTTGGAACTGGGTTTG CTTGTTCCAGCAAAAATGAAATGGCTTTAGTGCAAGAATTGGGTGTATCTCCAGAAAACATCATTTTCAC AAGTCCTTGTAAGCAAGTGTCTCAGATAAAGTATGCAGCAAAAGTTGGAGTAAATATTATGACATGTGAC AATGAGATTGAATTAAAGAAAATTGCAAGGAATCACCCAAATGCCAAGGTCTTACTACATATTGCAACAG AAGATAATATTGGAGGTGAAGATGGTAACATGAAGTTTGGCACTACACTGAAGAATTGTAGGCATCTTTT GGAATGTGCCAAGGAACTTGATGTCCAAATAATTGGGGTTAAATTTCATGTTTCAAGTGCTTGCAAAGAA TATCAAGTATATGTACATGCCCTGTCTGATGCTCGATGTGTGTTTGACATGGCTGGAGAGTTTGGCTTTA CAATGAACATGTTAGACATCGGTGGAGGCTTCACAGGAACTGAAATTCAGTTGGAAGAGGTTAATCATGT TATCAGTCCTCTGTTGGATATTTACTTCCCTGAAGGATCTGGCATTCAGATAATTTCAGAACCTGGAAGC TACTATGTATCTTCTGCGTTTACACTTGCAGTCAATATTATTGCTAAGAAAGTTGTTGAAAATGATAAAT TTTCCTCTGGAGTAGAAAAAAATGGGAGTGATGAGCCAGCCTTCGTGTATTACATGAATGATGGTGTTTA TGGTTCTTTTGCGAGTAAGCTTTCTGAGGACTTAAATACCATTCCAGAGGTTCACAAGAAATACAAGGAA GATGAGCCTCTGTTTACAAGCAGCCTTTGGGGTCCATCCTGTGATGAGCTTGATCAAATTGTGGAAAGCT GTCTTCTTCCTGAGCTGAATGTGGGAGATTGGCTTATCTTTGATAACATGGGAGCAGATTCTTTCCACGA ACCATCTGCTTTTAATGATTTTCAGAGGCCAGCTATTTATTTCATGATGTCATTCAGTGATTGGTATGAG ATGCAAGATGCTGGAATTACTTCAGATGCAATGATGAAAAACTTCTTCTTTGCACCCTCTTGTATTCAGC TGAGCCAAGAAGACAGCTTTTCCACTGAAGCTTAAACAGGCATTAACGCTTCCTTAGATCTGAAGTCGCA GGTTAAGCTTGTCTGGTCTACATTCCAGTGTGGGGGGAAAAAAATCAATCTTTATTCTGTTAATTTCTTG GAAACAAATTCATAGTAATAGCTATTTGGGACCAGACAAAATCAGCTTTCATCTATAATTCATTGGGGGT AATAGGGGATTTAGATAATGTATCCAGAGTTAAACATACCAGTTTGACCCACCCCTTAAGCGTTTAAAAT AAAATATGCAACAAAATGGATGACTTAGTGGAGATGGAAGCCCATTAACTGGGTTCCCCATCAAATCGTT TACATACAAGTACACAGTTTTTATAAGGATTCCTGTTAAAAGTCTTGTAAAGTTGATGTCTTTCACCCAG ATATATCACATGTGAGTGGAAGACCAGTGTGACTTCATTAGATACGTTTAGTGTATTTAGGATGTGTAAA TTTGTGCTTTTGAACTGTAGTTTAATAAATGTAAAATTGCATCATAGTATTTGTTGTATTTGACCTAATG TAACCCTTGTATGATTGCAATAAAACTTTGTGTAGATCTTAAAAAAAAAAAAAAAAA |
| Restriction Sites | RsrII-NotI |
| ACCN | NM_018745 |
| Insert Size | 1347 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC019412, AAH19412 |
| RefSeq Size | 2507 bp |
| RefSeq ORF | 1347 bp |
| Locus ID | 54375 |
| UniProt ID | O35484 |
| Gene Summary | The protein encoded by this gene belongs to the antizyme inhibitor family, which plays a role in cell growth and proliferation by maintaining polyamine homeostasis within the cell. Antizyme inhibitors are homologs of ornithine decarboxylase (ODC, the key enzyme in polyamine biosynthesis) that have lost the ability to decarboxylase ornithine; however, retain the ability to bind to antizymes. Antizymes negatively regulate intracellular polyamine levels by binding to ODC and targeting it for degradation, as well as by inhibiting polyamine uptake. Antizyme inhibitors function as positive regulators of polyamine levels by sequestering antizymes and neutralizing their effect. This gene encodes antizyme inhibitor 1, the first member of this gene family that is ubiquitously expressed, and is localized in the nucleus and cytoplasm. Overexpression of antizyme inhibitor 1 gene has been associated with increased proliferation, cellular transformation and tumorigenesis. Gene knockout studies showed that homozygous mutant mice lacking functional antizyme inhibitor 1 gene died at birth with abnormal liver morphology. RNA editing of this gene, predominantly in the liver tissue, has been linked to the progression of hepatocellular carcinoma. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Sep 2014] Transcript Variant: This variant (2) lacks an internal 5' non-coding exon, thus has a shorter 5' UTR compared to variant 1. Variants 1 and 2 encode the same isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG207146 | Azin1 (tGFP-tagged) - Mouse antizyme inhibitor 1 (Azin1) |
CNY 3,710.00 |
|
| MG221901 | Azin1 (tGFP-tagged) - Mouse antizyme inhibitor 1 (Azin1) transcript variant 2, (10ug) |
CNY 3,710.00 |
|
| MR221901 | Azin1 (Myc-DDK-tagged) - Mouse antizyme inhibitor 1 (Azin1), transcript variant 2 |
CNY 3,656.00 |
|
| MR221901L3 | Lenti ORF clone of Azin1 (Myc-DDK-tagged) - Mouse antizyme inhibitor 1 (Azin1), transcript variant 2 |
CNY 5,230.00 |
|
| MR221901L4 | Lenti ORF clone of Azin1 (mGFP-tagged) - Mouse antizyme inhibitor 1 (Azin1), transcript variant 2 |
CNY 5,230.00 |
