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Thbd (NM_009378) Mouse Untagged Clone
CAT＃: MC205512
Thbd (untagged) - Mouse thrombomodulin (Thbd), (10ug)
CNY 4,304.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | AI385582; CD141; TM |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC019154
CCACGCGTCCGGCAGGGACTAGGAGCCTGGGCTAGAAACGTCTAGGTTGTGATAGAGGCTAGCTGCTGTC GCCGCAGGCATACGGAAACCCCTCTGCCTGGACTGGGTGTCTGCACCAGCGCAGGGCTAGCTTTTCTCGG AACTTGCACGGTGCACCCCTGGACAGCATGCTTGGGATTTTCTTTCTGGGTGTGCTGGCTCCAGCTAGCC TGGGGCTCTCCGCACTAGCCAAGCTGCAGCCCACAGGCAGTCAATGCGTGGAGCATGAGTGCTTCGCGCT TTTCCAGGGCCCCGCGACCTTCCTCGATGCCAGCCAGGCCTGCCAGCGCCTGCAAGGACATTTGATGACA GTGCGCTCCTCAGTGGCTGCCGATGTCATCTCCCTTCTGCTGAGCCAGAGCAGTATGGATTTAGGGCCCT GGATCGGTTTACAGCTCCCGCAGGGCTGTGACGACCCGGTGCATCTCGGGCCCCTGCGCGGCTTCCAGTG GGTTACTGGCGATAACCACACCAGTTACAGCAGGTGGGCGCGGCCCAACGACCAGACGGCTCCACTCTGC GGCCCTCTGTGCGTCACGGTCTCGACAGCAACTGAAGCTGCACCCGGCGAGCCGGCCTGGGAAGAGAAGC CATGCGAGACTGAGACCCAGGGTTTCCTCTGTGAGTTTTACTTCACAGCTTCCTGCAGGCCTCTGACGGT GAATACTCGCGATCCTGAGGCTGCCCACATCTCTAGTACCTACAACACCCCGTTCGGGGTCAGTGGTGCG GACTTTCAAACGCTGCCGGTAGGCAGTTCCGCCGCGGTGGAGCCCCTTGGCTTGGAGCTGGTGTGCAGGG CCCCGCCCGGAACTTCAGAGGGACACTGGGCTTGGGAAGCGACAGGAGCCTGGAATTGCAGCGTGGAGAA TGGTGGCTGTGAGTACTTGTGCAATAGGAGCACGAATGAACCCAGATGCCTCTGCCCCAGAGACATGGAC CTGCAGGCCGATGGACGTTCGTGTGCAAGACCTGTGGTTCAATCGTGCAACGAACTCTGCGAGCATTTTT GTGTCAGCAACGCTGAAGTGCCAGGCTCTTACTCCTGTATGTGTGAGACAGGCTACCAGTTGGCTGCAGA CGGACACCGGTGTGAGGACGTGGATGACTGTAAGCAGGGGCCCAATCCATGTCCCCAGCTCTGTGTTAAC ACCAAGGGCGGCTTCGAATGCTTCTGCTATGATGGCTATGAGTTGGTGGATGGAGAGTGCGTGGAGCTTC TGGATCCGTGTTTCGGATCTAACTGCGAGTTTCAGTGCCAGCCAGTGAGCCCCACCGACTACCGATGCAT CTGCGCTCCGGGCTTCGCACCCAAGCCGGATGAACCGCACAAGTGCGAAATGTTCTGCAATGAAACTTCG TGCCCAGCAGACTGTGACCCTAACTCTCCTACTGTTTGTGAATGCCCTGAAGGCTTCATCCTGGACGAGG GTTCCGTATGCACGGACATTGATGAGTGCAGTCAAGGTGAATGCTTCACCAGTGAATGTCGAAACTTCCC TGGCTCCTATGAGTGTATCTGCGGGCCTGACACAGCCCTTGCTGGTCAGATTAGCAAAGACTGTGACCCC ATCCCTGTTAGGGAAGACACCAAGGAAGAGGAGGGCTCTGGGGAGCCTCCAGTCAGCCCTACGCCAGGCT CTCCGACAGGTCCCCCTTCTGCAAGGCCAGTGCACTCTGGCGTGCTCATTGGCATCTCCATTGCCAGCCT GTCCCTGGTGGTGGCGCTTTTGGCGCTTCTCTGTCACCTGCGCAAGAAGCAGGGCGCTGCTCGCGCAGAG CTGGAGTACAAGTGCGCATCTTCCGCCAAGGAGGTAGTGCTGCAGCACGTCAGGACTGATCGGACGCTGC AGAAGTTCTGAGGGATTTGCTCCAGAGACCCAGGTGGCCTTTGTCTTTCCGGGCTCTGTACCTCTCCTCT CCTCTCTCTCTCTTCAGCCTCCCAGCTGTGTTCTCTGGCAACTTAAAAGCATCCTGGCTGGTATAATAAC CAGAGAAGAGCCCATCCTCTCAGGACAAGCGAGGGTAGGGAGGACTGGAAGCAGGACAGCCCAGTTTCTT CCAAGTAGATACTGGACAACTGGGCGGAGGTGGCAAATACAGCGGAGATCCCAGAGTACCCCAGTCCCTC ACCTCACCTCCTAGTGCTGCTGATCTGTAGGCTTGAAGGCAAACCTTGACCCCATGGGCTGGAGATGACC CAGATATTTATTTTTTTTAAAAGTATTTAGTATTTTCTTCCCTCCAGTTTTCTTCTGCTTGTAAGTCTCC AGCCCCCCACCGCTTTCTCAGTCCCTCCATTCCCCCCTCCTGTCATTCTCCTCCCCAAACCTGATCATAA CTTTGCCCTTACCGTTGTTTCCAAACTCTTATGTGAAACAGAAAATAACACTAAAAGCAGAAAACGTTCT TTTTCACTGGCTTTGGGTATTTAGTCAGAAATTTCAGGTAACCAAAGCAAAAGAATTTTAACAAAAGCTA AAATATTTCAGCTGAACACTAACTAGTCAATAGTGCTGGAATGTCACAGAAAATAAACTTAAGGAAGTAG GGTTTTTTTTTTGAAATCTTTGTTTTTGAAAAGGGTGAGCCTGGGTTTTATGATTGTTGCTGTTGTTTTG AATGGGAATGACAAAAGAGGTCATTATTGTTAAGATTTTTATGCAGGCTCTACAGTGTTATTAATTTTTG ACAGTGTTCAAAATGTGCAGAGGATCCTTTGTCCAACCCTTTGACATGACAATAGGACATTGCTATCTTC AGACATACTGGGCCACATTCATAGCTTTCCAAGGATGTATGTGGTCCTGCCTCAACATATCAGAGACTGA CAGATGGAAGCATCTTCCAGTAAAGCATGAGTTGTGTGCTTCGTGCCGAGCTGACTCTCAACTGTGCTTG TCCCTTGTAGTCCCGAAATACAAGCAATGTGCTGCTTAGGGAAACATGGAAACTTGGGAATGGAGTCTGG GGGTGCCTAGATGGGGCTTTCTTTTAATGAGACTCTTGAACAATATCTCGTAATTCAGAGGGATCTTCTA GCCCTGGCCACTGGCCTGTACACAAGAATTGGGACCTCGCTTGGGATCTGGCTAGAATTGCAAAATCCTA GCCCCCACCCCTGCCCCACCCCAGTGTGCCAGTTCATAAGAATCTGCATTTTGACAACATCCACAGGGAC ATTGTCCAGTCATTTCAGGACAACTGGTCTTAAGAGTTTCCAACCTTTGTAGAACATTTAAATGTCGGTT AATAATAAGTAGCAGGCCATGTTAAGGCCATTTATTATCAAGAAACTGAGGAATTTTCTCTGCATAGCTT TGCTTTCTGGATACAATAAAATGAGAAGGTACACACCTCTAGATAGTGCCACACAGAGTCCAGAAGGGTT TTGTTTTAAGTAAGCTAGGAATGAGTTCATATGTTAGTGTAAGGAACAAATGTATTATATGTGTATCTTT TGTAAAGAAAGGTTTTTCTTTACGGTTTTGTAAGCTCAGCATATTTGTACATATTTATTTATTGGAGTTT CGCTAGAACACAAGCAAAGCCTTTGCTTATGACGTCACATGTACAAAATAAATAGATGACAGTGTAAAAA AAAAAAAAAA |
| Restriction Sites | RsrII-NotI |
| ACCN | NM_009378 |
| Insert Size | 1734 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC019154, AAH19154 |
| RefSeq Size | 3650 bp |
| RefSeq ORF | 1734 bp |
| Locus ID | 21824 |
| UniProt ID | P15306 |
| Gene Summary | Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.[UniProtKB/Swiss-Prot Function] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Dual targeting of therapeutics to endothelial cells: collaborative enhancement of delivery and effect
,Greineder, CF;Brenza, JB;Carnemolla, R;Zaitsev, S;Hood, ED;Pan, DC;Ding, BS;Esmon, CT;Chacko, AM;Muzykantov, VR;,
FASEB J.
,PubMed ID 25953848
[THBD]
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Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG209049 | Thbd (tGFP-tagged) - Mouse thrombomodulin (Thbd) |
CNY 5,510.00 |
|
| MR209049 | Thbd (Myc-DDK-tagged) - Mouse thrombomodulin (Thbd) |
CNY 4,304.00 |
|
| MR209049L3 | Lenti ORF clone of Thbd (Myc-DDK-tagged) - Mouse thrombomodulin (Thbd) |
CNY 6,940.00 |
|
| MR209049L4 | Lenti ORF clone of Thbd (mGFP-tagged) - Mouse thrombomodulin (Thbd) |
CNY 6,940.00 |
