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Lgals8 (NM_018886) Mouse Untagged Clone
CAT＃: MC205397
Lgals8 (untagged) - Mouse lectin, galactose binding, soluble 8 (Lgals8), transcript variant 2, (10ug)
CNY 2,400.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 1200015E08Rik; AI326142; D13Ertd524e; Lgals-8 |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC040243
CACTGTTCCCGGACCGGAATCCGAGTGTGGACACGGCATCCCGCCGTCTCCTCCGTGACACATGCACGGG GCACCGGACACCGGGAGCGATCGTGGGTTGAGGCTTGTACTGGGACCGTAGTGTCGGGACAACGCTGACT GCTGCGGACAAGTTTTTACTTTGAGTAATCCTTAAATGAAGAGTGGGTAAAGTGTGTATACGGAAGAGAG ACTCCAATCAACAATATCAATAAGTTGAAAAAGAAAAATGTTGTCCTTAAATAACCTACAAAATATCATC TATAACCCGATAATCCCCTATGTTGGCACCATTACTGAGCAATTGAAGCCTGGCTCTCTGATTGTAATCC GTGGGCATGTCCCTAAAGATTCAGAAAGATTCCAGGTTGACTTTCAGCTGGGCAACAGCCTGAAGCCAAG AGCAGACGTGGCCTTCCACTTTAACCCTCGGTTCAAAAGGTCTAGCTGCATTGTTTGTAACACACTGACA CAGGAGAAGTGGGGCTGGGAGGAGATCACCTACGACATGCCCTTCAGAAAAGAAAAGTCCTTTGAGATCG TGTTCATGGTGCTCAAGAACAAATTCCAGGTGGCTGTGAACGGAAGGCATGTTCTGCTGTACGCCCACAG GATCAGCCCGGAGCAGATCGACACAGTGGGCATCTACGGCAAAGTGAACATCCACTCCATCGGGTTCAGA TTCAGCTCGGATTTACAGAGTATGGAAACATCTGCTCTGGGACTGACACAGATAAACAGAGAGAATATAC AAAAGCCAGGCAAGCTCCAGCTGAGCCTGCCATTTGAAGCAAGGTTGAATGCCTCCATGGGTCCTGGACG AACCGTTGTCATTAAAGGGGAAGTGAACACCAATGCCCGAAGCTTTAATGTTGACCTAGTGGCAGGAAAA ACAAGGGATATCGCTCTGCACTTGAACCCACGCCTCAATGTGAAAGCATTTGTAAGAAATTCCTTTCTTC AGGATGCCTGGGGAGAAGAGGAGAGAAATATTACCTGCTTCCCATTTAGTTCTGGGATGTACTTTGAGAT GATAATCTACTGTGATGTCCGGGAATTCAAGGTTGCTATAAATGGTGTGCACAGCCTGGAGTACAAACAC AGATTTAAAGACCTAAGCAGTATTGATACACTATCAGTCGATGGTGATATCCGTTTGCTGGATGTAAGGA GCTGGTAGCTACCATGACTGCCAAAACCCCCGAAATACAAAATGGCTTATCCGGTACTGGCCATGTCAAA TGCATCTCGCTTTCACCATATTGTTTATATTGCTAAGTTGAGCTCCTCCAACATCAAGTCCTACTGGTGT TGTCAGGTCTGGCCATGCAGTACATTCAGAGGAACAGAGCCGGGGCAATCACAGCTCACTGCCAGAGAGG CTCTGCACACTGGGTCCCTCTTATAAACCACACTCAGCAAATATTTAAGTGCCTAATATACTACATATAC TAGCTAATAGGGATGGCAAGCATACTTCCTTTGTATATTCTCTGAGCCGGGCACAGACATGGCAGGGCCC AGAACTTGTGTGGTCCATGTTTTCTAGCACTTCGTACCAGTTTCTGGCCTCCTAATGTAGGGTCTTCTTG CTGGCATTGCATTAACCCCACTAGGGGCCTTTGCAGTTAAGGTCAGAAAAATATACTAATGGATGGCAAA CACTACTTCCCCAGCAACCCTTTTCATAATCAGCATTCTATCATATCTCATAATTGAAGACTGCATAGCA TTTACTTAGCTCTCACCGCTTTAAACTTTATAAAATGTATGATGCTGAACACAGCAGAAAAACTGAGGCC AAAACCCTGAATTATGACAAAACAAGTGTTCTGCTCCAAGCAGATTTCTGCTGGTTGATTGGCGCTCAAG TCCAGGGTGTGTGGGTACCTGTGGCAAAGTAAGGCAGAAGTTGGATAAACCGTGTGTGTAAAACCCTCTT GGACGTATATATAAAACAAGCACTATCAAAGCAAACCCAGGGGCGTAGTGTGAAAGGCTTAGTTGGTGTG GAGACTAGCCCTCGTGCCTTTGGGTCTGAAGATGTCGGTCTGCAGCAGCAGCGAGGTCAGGCACATTAAA CCACAGGACAGAATTCTGCTGGGGTTTAGGAGTATTCAGCCAATCTGCTTAGATATATGCACTTGTGCAT ATGAAATAATACCATCAGCAGTCTTACTCAAGGCAGCAACTGCTAGTCCTTCATTTTCATGCAAATTTAT TATGTTCACTCTTCAATATGGGGTGGTGGGTGGAACTGGGTAATTTGTACGGAGGCCAGGAGGCTCTAGA ATTCTCCAGAGTTATGTCTTCATAAAGAATGAGTCTTCATAAAGAATGCACTACTGAGATATTGGGGGCT CAAAGGCACTCAGGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | RsrII-NotI |
| ACCN | NM_018886 |
| Insert Size | 951 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC040243, AAH40243 |
| RefSeq Size | 2441 bp |
| RefSeq ORF | 951 bp |
| Locus ID | 56048 |
| UniProt ID | Q9JL15 |
| Gene Summary | Beta-galactoside-binding lectin that acts as a sensor of membrane damage caused by infection and restricts the proliferation of infecting pathogens by targeting them for autophagy. Detects membrane rupture by binding beta-galactoside ligands located on the lumenal side of the endosome membrane; these ligands becoming exposed to the cytoplasm following rupture. Restricts infection by initiating autophagy via interaction with CALCOCO2/NDP52. Required to restrict infection of bacterial invasion such as S.typhimurium. Also required to restrict infection of Picornaviridae viruses. Has a marked preference for 3'-O-sialylated and 3'-O-sulfated glycans.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) differs in the 5' UTR and uses an alternate in-frame splice site in the 5' coding region, compared to variant 3. Variants 1 and 2 encode the same isoform (1), which is shorter than isoform 2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG204541 | Lgals8 (tGFP-tagged) - Mouse lectin, galactose binding, soluble 8 (Lgals8) |
CNY 2,850.00 |
|
| MR204541 | Lgals8 (Myc-DDK-tagged) - Mouse lectin, galactose binding, soluble 8 (Lgals8), transcript variant 2 |
CNY 2,400.00 |
|
| MR204541L3 | Lenti ORF clone of Lgals8 (Myc-DDK-tagged) - Mouse lectin, galactose binding, soluble 8 (Lgals8), transcript variant 2 |
CNY 4,750.00 |
|
| MR204541L4 | Lenti ORF clone of Lgals8 (mGFP-tagged) - Mouse lectin, galactose binding, soluble 8 (Lgals8), transcript variant 2 |
CNY 4,750.00 |
