United States
Germany
Japan
United Kingdom
China
Pde9a (NM_008804) Mouse Untagged Clone
CAT＃: MC204906
Pde9a (untagged) - Mouse phosphodiesterase 9A (Pde9a), transcript variant 1, (10ug)
CNY 3,984.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | PDE9A1 |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC061163
AAGGTGAAAAAGTCCAAGTGCAGCTGCGGGCGCGATGGGGGCCGGCTCCTCAAGCTACCGGCCCAAGGCC ATCTACCTAGACATCGATGGACGCATCCAGAAGGTGGTTTTCAGCAAGTACTGCAACTCCAGTGACATCA TGGACCTGTTCTGTATCGCCACCGGCCTGCCTCGGAACACCACCATCTCCCTTTTAACCACAGACGACGC CATGGTCTCCATCGATCCCACCATGCCTGCGAATTCAGAGCGCACTCCCTACAAGGTGAGACCTGTGGCT GTGAAGCAAGTGTCTGAACGAGAAGAACTTATCCAGGGCGTGCTGGCCCAGGTGGCGGAACAATTTTCCA GAGCGTTTAAGATCAACGAGCTGAAAGCCGAAGTTGCAAATCACCTGGCCGTGCTGGAGAAACGGGTGGA ATTGGAAGGACTTAAAGTGGTGGAGATCGAAAAATGCAAGAGTGACATTAAAAAGATGCGGGAGGAGTTG GCAGCTAGGAACAGCAGGACCAACTGTCCATGTAAATACAGTTTTTTGGATAACAAGAAGTTGACACCTC GACGTGATGTCCCCACTTACCCCAAGTACCTGCTCTCCCCAGAGACCATCGAAGCCCTACGGAAGCCCAC CTTTGATGTCTGGCTTTGGGAACCCAACGAGATGCTGAGCTGTTTAGAACATATGTACCACGACCTTGGT CTGGTCAGGGACTTCAGCATCAACCCAATCACGCTCCGCAGGTGGCTGCTCTGTGTGCATGACAACTACA GGAACAACCCCTTCCACAACTTCCGGCACTGCTTCTGTGTGACACAGATGATGTACAGTATGGTCTGGCT CTGTGGCCTCCAGGAGAAGTTTTCCCAGATGGACATCTTGGTCCTGATGACTGCAGCCATCTGCCATGAC CTGGACCACCCAGGGTACAACAATACATACCAGATCAATGCCCGCACGGAACTCGCTGTGCGCTACAACG ACATCTCACCGCTGGAGAACCACCACTGCGCCATTGCCTTCCAGATCCTGGCAAGACCTGAGTGCAACAT CTTCGCCAGTGTGCCACCCGAGGGCTTCAGGCAGATCAGGCAGGGGATGATCACATTGATCCTGGCTACC GACATGGCAAGGCATGCTGAAATTATGGATTCTTTCAAAGAAAAGATGGAGAATTTTGACTACAGCAACG AGGAGCACCTGACCCTGCTGAAGATGATTCTCATAAAATGCTGTGATATCTCCAATGAAGTCCGTCCCAT GGAGGTGGCAGAACCGTGGGTGGACTGTTTACTGGAAGAATATTTTATGCAGAGTGACCGTGAGAAGTCC GAAGGCCTTCCTGTGGCCCCATTCATGGACCGAGACAAAGTGACCAAAGCAACAGCCCAAATTGGGTTCA TCAAGTTTGTCCTGATCCCAATGTTTGAAACAGTGACCAAGCTCTTCCCCGTTGTTGAGGAGACCATGCT GCGGCCGCTCTGGGAGTCCCGAGAACACTACGAGGAGCTGAAGCAGCTGGACGATGCCATGAAGGAGTTG CAGAAGAAGACAGAGAGCTTAACATCTGGGGCCCCGGAAAACACCACAGAGAAGAACAGAGATGCAAAAG ACAGTGAAGGCCATTCTCCTCCAAACTGATGGACATCTCAATGTGTGCAACTGTACCAGTTAGAGCAGAT GAATTGTGGCCTGTGAGTGGACAGAGCCAAGCGAGGCTTCCCAGGATCTTCCACACAAGGATGGTCACGC CCAGACGACCCCTGATGACCTGCTACAGACCATGTTTTCTAAGAACCATTTTGTTCACTGATATAAAAAC AGGAATTCACAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | SfiI-SfiI |
| ACCN | NM_008804 |
| Insert Size | 1605 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC061163, AAH61163 |
| RefSeq Size | 1860 bp |
| RefSeq ORF | 1605 bp |
| Locus ID | 18585 |
| UniProt ID | O70628 |
| Gene Summary | Specifically hydrolyzes the second messenger cGMP, which is a key regulator of many important physiological processes (PubMed:9624145). Highly specific: compared to other members of the cyclic nucleotide phosphodiesterase family, has the highest affinity and selectivity for cGMP. Specifically regulates natriuretic-peptide-dependent cGMP signaling in heart, acting as a regulator of cardiac hypertrophy in myocytes and muscle. Does not regulate nitric oxide-dependent cGMP in heart (PubMed:25799991). Additional experiments are required to confirm whether its ability to hydrolyze natriuretic-peptide-dependent cGMP is specific to heart or is a general feature of the protein (Probable). In brain, involved in cognitive function, such as learning and long-term memory (PubMed:22328573, PubMed:24746365).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG208559 | Pde9a (tGFP-tagged) - Mouse phosphodiesterase 9A (Pde9a) |
CNY 5,040.00 |
|
| MR208559 | Pde9a (Myc-DDK-tagged) - Mouse phosphodiesterase 9A (Pde9a), transcript variant 1 |
CNY 3,976.00 |
|
| MR208559L3 | Lenti ORF clone of Pde9a (Myc-DDK-tagged) - Mouse phosphodiesterase 9A (Pde9a), transcript variant 1 |
CNY 6,460.00 |
|
| MR208559L4 | Lenti ORF clone of Pde9a (mGFP-tagged) - Mouse phosphodiesterase 9A (Pde9a), transcript variant 1 |
CNY 6,460.00 |
