United States
Germany
Japan
United Kingdom
China
Sema4a (NM_013658) Mouse Untagged Clone
CAT＃: MC204159
Sema4a (untagged) - Mouse sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A (Sema4a), transcript variant 1, (10ug)
CNY 5,576.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | AI132332; Semab; SemB |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC025800
GTGCCTGGAGGGCCGCGCGCCCGTTCCAGCCAGGCTGAGCCTGCTTGCCTTGCCTGGACCCCCTTCTTTG CCTCGGATGGCACCCTGATTCAGGGTTTGAACACAGGACTTCTCAGTGTGGCTGGCTCAAGGAACCATCT GGTGACCATCTCAGGCTGACCATGGCCCTACCATCCCTGGGCCAGGACTCATGGAGTCTCCTGCGTGTTT TTTTCTTCCAACTCTTCCTGCTGCCATCACTGCCACCTGCTTCTGGGACTGGTGGTCAGGGGCCCATGCC CAGAGTCAAATACCATGCTGGAGACGGGCACAGGGCCCTCAGCTTCTTCCAACAAAAAGGCCTCCGAGAC TTTGACACGCTGCTCCTGAGTGACGATGGCAACACTCTCTATGTGGGGGCTCGAGAGGCCGTCCTGGCCT TGAATATCCAGAACCCAGGAATCCCAAGGCTAAAGAACATGATACCCTGGCCAGCCAGTGAGAGAAAAAA GACCGAATGTGCCTTTAAGAAGAAGAGCAATGAGACACAGTGTTTCAACTTCATTCGAGTCCTGGTCTCT TACAATGCTACTCACCTCTATGCCTGTGGGACCTTTGCCTTCAGCCCTGCCTGTACCTTCATTGAACTCC AAGATTCCCTCCTGTTGCCCATCTTGATAGACAAGGTCATGGACGGGAAGGGCCAAAGCCCCTTTGACCC TGTTCACAAGCACACAGCTGTCTTGGTCGATGGGATGCTTTATTCCGGCACCATGAACAACTTCCTGGGC AGCGAGCCCATCCTGATGCGGACACTGGGATCCCAGCCTGTTCTCAAGACTGACATCTTCTTACGCTGGC TGCACGCGGATGCCTCCTTCGTGGCAGCCATTCCATCCACCCAGGTCGTCTATTTCTTCTTTGAGGAGAC AGCCAGCGAGTTTGACTTCTTTGAAGAGCTGTATATATCCAGGGTGGCTCAAGTCTGCAAGAACGACGTG GGCGGTGAAAAGCTGCTGCAGAAGAAGTGGACCACCTTCCTCAAAGCCCAGTTGCTCTGCGCTCAGCCAG GGCAGCTGCCATTCAACATCATCCGCCACGCGGTCCTGCTGCCCGCCGATTCTCCCTCTGTTTCCCGCAT CTACGCAGTCTTTACCTCCCAGTGGCAGGTTGGCGGGACCAGGAGCTCAGCAGTCTGTGCCTTCTCTCTC ACGGACATTGAGCGAGTCTTTAAAGGGAAGTACAAGGAGCTGAACAAGGAGACCTCCCGCTGGACCACTT ACCGGGGCTCAGAGGTCAGCCCGAGGCCAGGCAGTTGCTCCATGGGCCCCTCCTCTGACAAAGCCTTGAC CTTCATGAAGGACCATTTTCTGATGGATGAGCACGTGGTAGGAACACCCCTGCTGGTGAAGTCTGGTGTG GAGTACACACGGCTTGCTGTGGAGTCAGCTCGGGGCCTTGATGGGAGCAGCCATGTGGTCATGTATCTGG GTACCTCCACGGGGTCCCTGCACAAGGCTGTGGTGCCTCAGGACAGCAGTGCTTATCTCGTGGAGGAGAT TCAGCTGAGCCCTGACTCTGAGCCTGTTCGAAACCTGCAGCTGGCCCCCGCCCAGGGTGCAGTGTTTGCA GGCTTCTCTGGAGGCATCTGGAGAGTTCCCAGGGCCAATTGCAGTGTCTACGAGAGCTGTGTGGACTGTG TGCTTGCCAGGGACCCTCACTGTGCCTGGGACCCTGAATCAAGACTCTGCAGCCTTCTGTCTGGCTCTAC CAAGCCTTGGAAGCAGGACATGGAACGCGGCAACCCGGAGTGGGTATGCACCCGTGGCCCCATGGCCAGG AGCCCCCGGCGTCAGAGCCCCCCTCAACTAATTAAAGAAGTCCTGACAGTCCCCAACTCCATCCTGGAGC TGCCCTGCCCCCACCTGTCAGCACTGGCCTCTTACCACTGGAGTCATGGCCGAGCCAAAATCTCAGAAGC CTCTGCTACCGTCTACAATGGCTCCCTCTTGCTGCTGCCGCAGGATGGTGTCGGGGGCCTCTACCAGTGT GTGGCGACTGAGAACGGCTACTCATACCCTGTGGTCTCCTATTGGGTAGACAGCCAGGACCAGCCCCTGG CGCTGGACCCTGAGCTGGCGGGCGTTCCCCGTGAGCGTGTGCAGGTCCCGCTGACCAGGGTCGGAGGCGG AGCTTCCATGGCTGCCCAGCGGTCCTACTGGCCCCATTTTCTCATCGTTACCGTCCTCCTGGCCATCGTG CTCCTGGGAGTGCTCACTCTCCTCCTCGCTTCCCCACTGGGGGCGCTGCGGGCTCGGGGTAAGGTTCAGG GCTGTGGGATGCTGCCCCCCAGGGGAAAGGCTCCACTGAGCAGGGACCAGCACCTCCAGCCCTCCAAGGA CCACAGGACCTCTGCCAGTGACGTAGATGCCGACAACAACCATCTGGGCGCCGAAGTGGCTTAAACAGGG ACACAGATCCGCAGCTGAGCAGAGCAAGCCACTGGCCTTGTTGGCTATGCCAGGCACAGTGCCACTCTGA CCAGGGTAGGAGGCTCTCCTGCTAACGTGTGTCACCTACAGCACCCAGTAGGTCCTCCCCTGTGGGACTC TCTTCTGCAAGCACATTGGGCTGTCTCCATACCTGTACTTGTGCTGTGACAGGAAGAGCCAGACAGGTTT CTTTGATTTTGATTGACCCAAGAGCCCTCCTGTAACAAACGTGCTCCAGGAGACCATGAAAGGTGTGGCT GTCTGGGATTCTGTGGTGACAAACCTAAGCATCCGAGCAAGCTGGGGCTATTCCTGCAAACTCCATCCTG AACGCTGTCACTCTAGAAGCAGCTGCTGCTTTGAACACCAGCCCACCCTCCTTCCCAAGAGTCTCTATGG AGTTGGCCCCTTGTGTTTCCTTTACCAGTCATGCCATACTGTTTGGGAAGTCATCTCTGAAGTCTAACCA CCTTCCTTCTTGCTTCAGTTTGGACAGATTGTTATTATTGTCTCTGCCCTGGCTAGAATGGGGGGCATAA TCTGAGCCTTGTTCCCTTGTCCAGTGTGGCTGACCCTTGACCTCTTCCTTCCTCCTCCCTTTGTTTTGGG ATTCAGAAAACTGCTTGTCACAGACAATTTATTTTTTATTAAAAAAGATATAAGCTTTAAAGAAAAAAAA AAAAAAAAA |
| Restriction Sites | RsrII-NotI |
| ACCN | NM_013658 |
| Insert Size | 2283 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC025800, AAH25800 |
| RefSeq Size | 3159 bp |
| RefSeq ORF | 2283 bp |
| Locus ID | 20351 |
| UniProt ID | Q62178 |
| Gene Summary | Cell surface receptor for PLXNB1, PLXNB2, PLXNB3 and PLXND1 that plays an important role in cell-cell signaling (PubMed:20043131, PubMed:17318185). Regulates glutamatergic and GABAergic synapse development (PubMed:29981480). Promotes the development of inhibitory synapses in a PLXNB1-dependent manner and promotes the development of excitatory synapses in a PLXNB2-dependent manner (PubMed:29981480). Plays a role in priming antigen-specific T-cells, promotes differentiation of Th1 T-helper cells, and thereby contributes to adaptive immunity (PubMed:15780988). Promotes phosphorylation of TIMD2 (PubMed:12374982). Inhibits angiogenesis (PubMed:17318185). Promotes axon growth cone collapse (PubMed:20043131). Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons (PubMed:20043131).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longest transcript. All four variants encode the same protein. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG210512 | Sema4a (tGFP-tagged) - Mouse sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A (Sema4a) |
CNY 9,952.00 |
|
| MG217855 | Sema4a (tGFP-tagged) - Mouse sema domain immunoglobulin domain (Ig) transmembrane domain (TM) and short cytoplasmic domain (semaphorin) 4A (Sema4a) transcript variant 1, (10ug) |
CNY 6,370.00 |
|
| MR217855 | Sema4a (Myc-DDK-tagged) - Mouse sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A (Sema4a), transcript variant 1 |
CNY 5,568.00 |
|
| MR217855L3 | Lenti ORF clone of Sema4a (Myc-DDK-tagged) - Mouse sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A (Sema4a), transcript variant 1 |
CNY 7,700.00 |
|
| MR217855L4 | Lenti ORF clone of Sema4a (mGFP-tagged) - Mouse sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A (Sema4a), transcript variant 1 |
CNY 7,700.00 |
