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Dclk2 (NM_027539) Mouse Untagged Clone
CAT＃: MC203532
Dclk2 (untagged) - Mouse doublecortin-like kinase 2 (Dclk2), transcript variant 2, (10ug)
CNY 2,000.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 6330415M09Rik; AU044875; CL2; Clic; Click-II; CLICK2; Dcamk; Dcamkl2 |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC056921
TCCCTCTCGGTGTGGTTTGTGGTGTCCCTGAAGGGACAGAGGGTGTCCTCCGGGGTCCAGGCCCTGACAG GCGGCCGAGAGCGCGGATGCCCGTGGGCGTGCGTGCGTGGGAGGCGGCTGCACTCTTCCCGCAGGGGCCC AGCGCCTCTAGAGGATCCCCGGCCAGGGACGCGCACCGGCCGTGGACTGGGCCTGGGCGCGCGCGACGCG GCGGCGGGAACCCGGGACCCCAGGCCGCGCCGGGCAGCCCCGAGGCGCCTCGCCCACGCTCGCGCCCCTC CCCCCTCCGCTTCCTTCCTCCACTCAGCGCGCCCGAGAGCGCAGGCCGGATGCGAACCCGGGCCAGCCTA GGGTCGTTCAACTTGGCGGCTCCCGGCCTGCTGCCCGCGCGCTACTTGTGAGGCGTGGCCCGGCGAAGGA GGCGCTTGGGGGGCGTGGGGCTCCTCAGCTGGCGGCGGCGACCGAGGGCGCGCGGGACAATGAGCTGGGC TGCTGCGCGCTGCGGCCGCCTTTAGCTGGCTGAGCGGCTCCACCTGCGAGCATGGCCCGAATGCCCGCGC CAGGTGTCCCGCTGCTTTAAGACGGGACGGAGCGCCTAGATCGCGGCGCGCTGCGGCCGGGGCGGTTGGG ACGTCCTTTTATTAATTAATTAATTTGTGGAGAGCTCTCCCGAGCAGCCGCGATGGCCAGCACAAGGAGC ATTGAGCTGGAACATTTTGAAGAACGGGACAAAAGGCCGCGGCCAGGGTCACGGAGAGGGGCTCCCAGCT CCTCCGGGGGCAGCAGCATCTCTGGCCCCAAGGGCAACGGGCTCATCCCCAGCCCGGCGCACAGTGCTCA CTGCAGCTTCTACCGCACGCGGACCTTGCAGGCCCTCAGCTCGGAGAAGAAGGCCAAGAAGGCGCGGTTC TACCGGAATGGGGACCGCTATTTCAAAGGCCTGGTCTTTGCCATCTCCAACGACCGTTTCCGTTCCTTCG ATGCGCTCCTCATAGAGCTCACCCGCTCACTGTCTGACAATGTGAACCTGCCCCAGGGCGTCCGCACCAT CTACACCATAGACGGCAGCCGGAAGGTCACCAGCCTGGACGAGCTGCTGGAAGGTGAAAGTTACGTGTGT GCCTCCAACGAACCATTTCGTAAAGTTGATTACACCAAAAACGTTAATCCGAACTGGTCTGTGAACATCA AGGGCGGAACCACCCGCACCCTGGCCGTGGCCTCTGCGAAGAGTGAGGTGAAAGAAAGCAAAGACTTCAT TAAACCCAAGTTAGTGACTGTGATTCGAAGCGGAGTGAAGCCTAGAAAGGCCGTGCGGATCCTTCTGAAT AAAAAGACTGCCCATTCCTTTGAGCAGGTCTTAACAGATATCACCGAAGCCATTAAACTAGACTCAGGCG TGGTCAAGAGGCTGTGCACCCTGGATGGAAAGCAGGTTACTTGTCTGCAAGACTTTTTTGGAGACGATGA TGTTTTTATTGCATGTGGACCTGAAAAATATCGTTATGCCCAAGATGACTTTGTCCTGGATCATAGCGAA TGCCGTGTCCTGAAATCGTCCTACTCTCGAGCCTCAGCTGCGAAGTATTCTGGATCCAGAAGCCCAGGGT TCTCCCGCCGCAGCAAGTCACCAGCTTCAGTGAATGGAACTCCCAGTAGCCAGCTTTCCACTCCGAAGTC CACCAAGTCCTCCAGCTCCTCTCCAACCAGCCCGGGAAGTTTCAGAGGATTGAAGCAGATTTCTGCTCAG GGCAGATCTTCTTCCAACGTAAACGGTGGGCCTGAACTTGACCGTTGCCTGAGCCCTGAAGGTGTGAATG GAAACCGGTGCTCCGAGTCGTTCCCCCTTCTGGAGAAATACAGAATAGGGAAGGTCATCGGGGACGGCAA CTTCGCGGTAGTTAAGGAGTGCGTGGACAGGTACACTGGAAAAGAGTTTGCATTAAAGATTATAGACAAA GCCAAATGCTGTGGAAAGGAGCATCTGATTGAGAACGAAGTGTCAATCCTGCGCCGAGTGAAGCACCCCA ACATCATCATGTTGGTTGAAGAGATGGAAACAGCAACTGACCTCTTTCTAGTGATGGAACTGGTCAAAGG TGGAGATCTCTTTGATGCGATTACCTCTTCAACCAAGTACACTGAGAGAGATGGAAGCGCCATGGTGTAC AACCTAGCCAATGCCCTCCGGTACCTGCACAGCCTCAGCATCGTCCACAGGGACATCAAGCCTGAGAATC TGCTGGTGTGCGAATACCCAGATGGAACCAAGTCTTTGAAGCTGGGAGACTTTGGGCTGGCGACGGTGGT TGAAGGCCCGTTGTACACGGTCTGTGGCACGCCAACTTATGTGGCACCAGAGATCATAGCTGAAACAGGT TATGGCCTGAAGGTGGATGTTTGGGCAGCTGGTGTGATTACATACATACTTCTCTGTGGATTCCCACCAT TCCGGAGTGAGAACAATCTCCAGGAAGATCTCTTTGACCAGATCTTGGCTGGAAAGCTGGAATTCCCAGC CCCCTACTGGGACAACATTACAGACTCTGCCAAGGAGTTAATCAGTCAAATGCTTCAGGTAAACGTTGAA GCTCGCTGTACTGCGGGAGAAATTCTGAGTCACCCCTGGGTGTCAGATGATGCATCCCAGGAGAACAATA TGCAAGCCGAGGTTACAGGTAAACTAAAACAGCACTTTAATAATGCGCTCCCCAAACAGAACAGCACCAC CACCGGGGTCTCCGTTATCATGAACACGGCTCTAGATAAAGAGGGGCAGATTTTCTGCAGCAAGCTCTGT CAAGACAGCAGCAGACCATCCAGGGAGCAGACCTCGCCAGTCCCTCCCTCAGCCCAGGAGGCCCCTCCCC CACTGGAGTCTCCCAGGCCCCCTGGTCCTCCAGCCACCTCTGGCTGTGATCTGGCAGGGACCTGGCGCCG CCACCGAGACTGAACCCTGTGTACACAGGCCAAAGCCGCTCACCGTGCCAGGCAGGCCGCTCTTCAGCGG GCCTCATCAACTCCTTGCTGAAAGAGCCTCTCTCTCCTGGCTGCTGCTTTGACAGTTTGTTGGCATGTTC TGTCACTGCCTGAGAACAGAACTGGGGCATCCTGGAGCCCGTGTGCAGCATGGCCTCATGCACTTTGGGC TCTGCCCTCTCTAGTTCCTGGCCATGTCAAGCAAGCCATGTCAGTTGTGGAGACATATTTGGAGTGACTC ATTTTAAATCATCTGTGTTTTTAGTTCAGTAGACACTTGGCCGCTTTCCCCAGAGAATGTGCAACTTTTA TCTGGAATTACATCGTTTTTACAGAAATGCATTGGACGAATTAGGATTCTCCTTATTGAAGGACACTCCA AGTGCTCCCTTCTCAGGACACAGCTATGGTTCCTTTGTTCTGTGAGAGGCAACATGGCCTCTTCGTCTTC ATAGGGCGCTGAGGCACCTGGCTTCTGACTAGGAGTGTCATTCTGACTTGAGAGGGTCATTTGCCTCCTG ACTTTGGGAAGTGCATTCTGAAGCCCCAGGAAGCAGATCCCGACCATCCGTCCGTCCGTCTGTCCGCTGG GCTGGGGTGCTGGGCTCGCAGACCTAGCTGACTCACCCTTGGTTTCCCGACTCTCCTTGTGTGTGTTTTA GGAAATGCTTATGAAGCTGGCCCGTGGGCTTCCCAGTGGGACGTGCAGCAGTTCTTGGCAGAGCAGGGCC AGCTCTGCTGTGTCATCTCCAGGGTCTCCCATCACCTCTGCTCTTTGCCATGGCAGGTCTGCTGAGACCC CGCGGGGACGGGGGCATGGTGCTCCCTGATTGGCCTGTGACCAACCTTCTGGAAGGCTGCTGGCAGTTTT CCCTGTTTTCCACCACCCCACTCTTTTTAATAATTGTATATAACTGTACTTGTTCTACTTGCTTGTCTTT AAAACAGGGGCCCCCACAGTTCACTCTCACTGTTAGATTTTGCCTTTTCCAGGTATCCCCAACCTGCAAT AAACTCTTCCCTCTTCAGAAAAAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | AscI-NotI |
| ACCN | NM_027539 |
| Insert Size | 2271 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | BC056921, AAH56921 |
| RefSeq Size | 4032 bp |
| RefSeq ORF | 2271 bp |
| Locus ID | 70762 |
| UniProt ID | Q6PGN3 |
| Gene Summary | This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmoduline-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. This gene and the DCX gene, another family member, share function in the establishment of hippocampal organization and their absence results in a severe epileptic phenotype and lethality, as described in human patients with lissencephaly. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Sep 2010] Transcript Variant: This variant (2) is an exon-5-lacking transcript (PMIDs:15611072 and 18075264). It lacks an in-frame coding exon and has an additional 3 nts at an alternate splice site, as compared to variant 1. The resulting isoform (2) is shorter; it lacks an internal segment but has a downstream extra aa, as compared to isoform 1. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG210491 | Dclk2 (tGFP-tagged) - Mouse doublecortin and CaM kinase-like 2 (Dcamkl2) |
CNY 8,270.00 |
|
| MG226381 | Dclk2 (tGFP-tagged) - Mouse doublecortin-like kinase 2 (Dclk2) transcript variant 2, (10ug) |
CNY 8,270.00 |
|
| MR226381 | Dclk2 (Myc-DDK-tagged) - Mouse doublecortin-like kinase 2 (Dclk2), transcript variant 2 |
CNY 7,510.00 |
|
| MR226381L3 | Lenti ORF clone of Dclk2 (Myc-DDK-tagged) - Mouse doublecortin-like kinase 2 (Dclk2), transcript variant 2 |
CNY 9,410.00 |
|
| MR226381L4 | Lenti ORF clone of Dclk2 (mGFP-tagged) - Mouse doublecortin-like kinase 2 (Dclk2), transcript variant 2 |
CNY 9,410.00 |
