Grk6 (NM_001038018) Mouse Untagged Clone
CAT#: MC203384
Grk6 (untagged) - Mouse G protein-coupled receptor kinase 6 (Grk6), transcript variant 1, (10ug)
CNY 4,392.00
Product images
![](https://cdn.origene.com/img/defaults-img.jpg)
Specifications
Product Data | |
Type | Mouse Untagged Clone |
Tag | Tag Free |
Synonyms | Gprk6 |
Vector | PCMV6-Kan/Neo |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>BC075719
CCCACGCGTCCGCCCACGCGTCCGGGCGCGGCCTGGCGGGCCGGGCGGCGCTGCAGCCCATGGAGCTCGA GAACATCGTAGCGAACACGGTGCTACTCAAGGCCCGGGAAGGTGGTGGCGGGAATCGCAAAGGCAAGAGC AAGAAATGGCGCCAGATGCTGCAGTTCCCCCATATCAGCCAGTGTGAGGAGCTTCGACTCAGCCTTGAGC GTGACTACCACAGCCTATGTGAGCGCCAGCCCATTGGGCGCCTGTTATTTCGTGAGTTCTGTGCTACGAG ACCTGAGCTGACCCGGTGTACTGCCTTCCTGGATGGGGTGTCTGAATATGAGGTGACCCCTGATGAGAAG CGGAAAGCATGTGGGCGCCGACTAATGCAGAACTTTCTGAGCCACACGGGTCCTGACCTCATCCCTGAAG TTCCACGGCAGCTGGTGAGTAACTGTGCCCAGCGGCTAGAGCAGGGACCCTGCAAAGACCTCTTCCAGGA GCTGACCCGGCTGACCCACGAGTACCTGAGCACGGCCCCTTTTGCCGACTACCTCGACAGCATCTACTTC AACCGTTTTCTGCAGTGGAAGTGGCTGGAAAGGCAACCAGTGACCAAAAACACCTTCAGGCAGTACCGAG TCCTGGGCAAAGGTGGCTTTGGGGAGGTATGTGCCTGCCAGGTGCGGGCAACAGGCAAGATGTACGCATG CAAGAAACTGGAAAAGAAGCGGATAAAGAAGCGAAAGGGGGAGGCCATGGCTCTCAACGAGAAACAGATC TTGGAGAAAGTGAACAGTAGGTTTGTAGTGAGCTTAGCCTACGCCTATGAGACCAAGGATGCACTGTGCC TGGTGCTGACATTGATGAATGGAGGTGACCTAAAGTTCCACATCTACCACATGGGCCAGGCTGGCTTTCC TGAAGCACGTGCTGTCTTCTATGCTGCTGAGATCTGCTGTGGCCTGGAAGACCTGCACCGGGAACGCATT GTGTACAGGGATCTAAAGCCAGAGAATATCCTTCTGGATGACCATGGCCACATTCGGATCTCGGACCTGG GACTGGCCGTGCATGTGCCTGAGGGCCAGACCATCAAAGGCCGTGTGGGCACTGTGGGCTACATGGCTCC AGAGGTGGTGAGGAATGAGCGCTACACGTTCAGTCCTGACTGGTGGGCGCTAGGCTGCCTCCTGTACGAG ATGATCGCAGGTCAGTCGCCCTTCCAGCAGAGGAAGAAGAAGATAAAGCGCGAAGAGGTGGAGCGGCTGG TCAAGGAAGTGGCCGAGGAGTACACAGACCGCTTTTCCTCACAGGCGCGCTCACTCTGTTCTCAGCTTCT TAGCAAGGACCCTGCTGAGCGCCTGGGGTGTCGTGGAGGTGGCGCCCGTGAGGTAAAGGAGCACCCCCTT TTCAAGAAACTGAATTTCAAGCGGCTGGGAGCTGGCATGCTAGAGCCACCTTTTAAGCCTGATCCCCAGG CTATTTATTGCAAGGATGTCCTGGACATTGAACAGTTCTCTACAGTTAAAGGTGTGGATCTGGAGCCCAC AGACCAAGACTTCTACCAGAAGTTTGCCACAGGCAGTGTGTCCATCCCCTGGCAGAATGAGATGGTGGAG ACCGAGTGCTTCCAGGAACTCAATGTCTTTGGGCTGGATGGGTCTGTTCCCCCAGACCTGGACTGGAAGG GCCAGCCCACTGCACCCCCCAAGAAGGGATTGCTACAGAGACTCTTCAGTCGCCAAAGGATTGCTGTGGG AACTGCAGCGACAGTGAGGAAGAGCTCCCCACCCGCCTCTAGCCCCCAGGCCGAGGCCCCCACCGGCGGT TGGCGGTAGCAGCTACTCTCGGTGACGTTTACAGTTTTGCACAGTGGTGTTCCCCATTTTCCACGCAAGC CGTGGATTGTGGAACACAGCCGGAACTGTCCCCAGTGTCCTCCGTTCCTCAGCCACTAGCCTAGCTGAGT TTGACAAGGCCTGGGCCATCTTGGGACAAAGGTGCGTCCCTTCAGCTCTCTGTGGAGCTCGGGGCTTTAT GTATTTATGTATTTGTATGAATGTATATAGCTACTAGAGCGTTCTTAATTCCACCCTGGACCTGGACACT CCAGGGCAATTAGCCCTGGCCAGGAAAGCCAGGAGCTGGCAAGAGGAGCCAGTGCCAAACTCCAGGCTTC TAGGGCCCAGTGGAGATGAGCAAGCAGAGAGTGGGCCAGGTCAGACCTCTGCCCACAGCACTGCACTGGC CACCACCAACCTCCAAGTGAGACTTGTGCCTGCCTGTTGTGGACTGAGGCCACCACCTTCTGGTTGCCTA ATGCTTTCCCTCTTTCTCAGCATTTGTCAGGGTTGGAGCTGGGGTCTTTGTATCCTCTAGGACTGGGACA TAGTTTAACCCCAGACTTAGCTGAGTGTGACCCATCAAACCACTGCCCGAGATGGGTCGCTTTCTGCCTT CCAGCTCCCAGAGCACAGTAGTCCTTATTCTGGGTCATATCCTGAAGACACCTTTTTCAGAAATGCCCCA GTCCAGGCCATAGGAGGAGTTAGAATTAGCCCTCCAACATTCCAGAATCCCTCATAAAAGTAGACACATG CCCAGCAATAATCCACCCTTCCCTGTGTGTGCCTGGTGGGGGTGGGGGTGAGTGTATATCATTGTGTGAA AAGAGTAGGGTAAGGCTGTGCCTAAGCCCCCGGACCCTAGCCCTGGCCTGTCCCAGACTGTGATGGCTGT CCTGATGCTAGTTAGGACAGCATGGGACCATAAGGCCCTGGCTTTTCCATATTTAAAGCCAATGTAAGCT GCCATGTGTCTCTATGTGACCAATGTGAGCTGCCACGTGTCTGTGCGAATACATTCTGAGCACACGGCTG GCCAGCCACCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA |
Restriction Sites | RsrII-NotI |
ACCN | NM_001038018 |
Insert Size | 1770 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | BC075719, AAH75719 |
RefSeq Size | 2924 bp |
RefSeq ORF | 1770 bp |
Locus ID | 26385 |
UniProt ID | O70293 |
Gene Summary | Specifically phosphorylates the activated forms of G protein-coupled receptors. Such receptor phosphorylation initiates beta-arrestin-mediated receptor desensitization, internalization, and signaling events leading to their desensitization. Seems to be involved in the desensitization of D2-like dopamine receptors in striatum and chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis (By similarity). Phosphorylates rhodopsin (RHO) (in vitro) and a non G-protein-coupled receptor, LRP6 during Wnt signaling (in vitro) (By similarity).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a). |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MG220063 | Grk6 (tGFP-tagged) - Mouse G protein-coupled receptor kinase 6 (Grk6) transcript variant 1, (10ug) |
CNY 6,460.00 |
|
MR220063 | Grk6 (Myc-DDK-tagged) - Mouse G protein-coupled receptor kinase 6 (Grk6), transcript variant 1 |
CNY 5,890.00 |
|
MR220063L3 | Lenti ORF clone of Grk6 (Myc-DDK-tagged) - Mouse G protein-coupled receptor kinase 6 (Grk6), transcript variant 1 |
CNY 7,790.00 |
|
MR220063L4 | Lenti ORF clone of Grk6 (mGFP-tagged) - Mouse G protein-coupled receptor kinase 6 (Grk6), transcript variant 1 |
CNY 7,790.00 |