Fgf1 (NM_010197) Mouse Untagged Clone

CAT#: MC203263

Fgf1 (untagged) - Mouse fibroblast growth factor 1 (Fgf1), (10ug)



  "NM_010197" in other vectors (4)

CNY 1,200.00

CNY 2,000.00


货期*
现货

规格
    • 10 ug

Product images

经常一起买 (3)
TurboFectin Transfection Reagent (1 mL in 1 vial)
    • 1 ml in 1 vial

CNY 4,090.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00


Forward sequencing primer VP1.5, Reverse sequencing primer XL39, 100pmoles each
    • 100 pmol

CNY 480.00

Specifications

Product Data
Type Mouse Untagged Clone
Tag Tag Free
Synonyms Dffrx; Fam; Fgf-1; Fgfa
Vector PCMV6-Kan/Neo
E. coli Selection Kanamycin (25 ug/mL)
Mammalian Cell Selection Neomycin
Sequence Data
>BC037601
CCACGCGTCCGCCCACGCGTCCGGGCGTGGGAGAAGCAAGGCCTGGGCTTCCAGCGCGCTGTAGCAAGGT GTTGGTGCTTCCCACAGCAGTAGGAATGCATTGGAGGGGTGTGACAATGGAACTCAGGTGACACTGCTGA TGAAGGAGCCCAAAGAACCAATATCTGACCTGTGCTGAGCCTACCACCGCTGCTTGCTGCCGAGCCATGG CTGAAGGGGAGATCACAACCTTCGCAGCCCTGACCGAGAGGTTCAACCTGCCTCTAGGAAACTACAAAAA GCCCAAACTGCTCTACTGCAGCAACGGGGGCCACTTCTTGAGGATCCTTCCTGATGGCACCGTGGATGGG ACAAGGGACAGGAGCGACCAGCACATTCAGCTGCAGCTCAGTGCGGAAAGTGCGGGCGAAGTGTATATAA AGGGTACGGAGACCGGCCAGTACTTGGCCATGGACACCGAAGGGCTTTTATACGGCTCGCAGACACCAAA TGAGGAATGTCTGTTCCTGGAAAGGCTGGAAGAAAACCATTATAACACTTACACCTCCAAGAAGCATGCG GAGAAGAACTGGTTTGTGGGCCTCAAGAAGAACGGGAGCTGTAAGCGCGGTCCTCGGACTCACTATGGCC AGAAAGCCATCTTGTTTCTGCCCCTCCCGGTGTCTTCTGACTAGAGGAGTCTGTTCTGAGTGTTCTCTAT TTTGGTTGACCCTACCATGTTCCCTTGACCATTGGCTGCGCTAACCCTCAGGCCACAGAGCCTGAATTTG TAAGCAGTGCTTCTAAAATAGCCAGTTCACTTTTCTGCTGAGCCCTTCCCCACCACCCCAGCACAATTTG GAACACAGGGACCAAATTGCTTCAAGAGGACAACTGGCTGGCCAGTCTAGGTCTGGGTTTGGATATCCGG ATGCCTCAGGGCACCTGCTACAAGCTGGACCTGGTGATGCAAAGTTGGGGGCCATACGAAGCATTCAAAG GGGTCTAAGAAGTGGGTTCTTAGAAAGATACCCACTGCATGCTCTTTCCCCTTCTGAGCAATCCCTGGTT TTAAGCACCCCAGGCAATTAGCATGACTACCCTTCCCCCTACCAGAACCGCACAAATATCAGTAAAGCAA CCGGTAGTGAGGCTGAAGGAATTTCATGGTAGAGAGAAACCCCCCCCCCCCAGCCCCCACATATGGACAA GACTTAAAACCAAAAGGGAGTGTGGCGTTTCCGGGACAGCCTAGAAGCATGGGATCTCGGAACAGAGTAA GAAGGCAAGAGTCAGCCACAGGGAGTCAGGATGAGCCCACAGCCCAGCAGTTATCACCAAGTTACCAAGG AAACGTCCACAGTCAGGGAAAGAGCCCCGGAAATGGTTTCTTAGTAATGGCAAGCACAGAGATCTGGGGT CTGAAGAGTGGGCGTAGGAGCAAGGAGACAGGATGTCTTCAGCCGTGGATGTTAGCCTCTAAAAAGGAAG ATGTTAGACGGGAGGAGGAGGAGAGAAAAAGTAATATCACGTCACTGTGTGCTTGGCCACCACGAAACTG GGGTTGTGGGGGTCCCAGTACGATGGCCCCAAATAGCCCATACATTCAGATCATCTGTATTCAGATTCAT TTGTATGACTGTGAAACCTGATTTGGTGGGGCTGGTGTGGGGGAGGTCTGTGTCTTGAAAGGCCCGCAAG TCCCATAGATGCTGCTGGCTTCCCCACCATGCTTTCAAGAGCAGCCCCAGAGAATGCTGTTCAAATGAAG GTTGCTCAGACTTCACCCTCTTTTACCTCCAGTGCCCGGGTTTTCCTGAGTATCCATCCAGGCAGTGTCC ATAGTTAGTGAAGCATGGTTTCAAGGCACCTTGGCCCAGTGCCTATAAAATGCCCACTCAGAAATCACTG AAACCGTACTTCAAAAAAAAATGTTGAACCTCACCAAAAGCTTTCTCCCAAGAGACCATTTCTGTTACCA TTAATTCTTCAAACTGGCTTCCTCCTTAAAGTAAACCTGGCCCAAGTGCCCAGCAAATTAGAAACACTAT TCATCTCTGACATAGGACACAAACGCCATGAGAAGGCCTTTCATACGCCAATTTAATATACTGTGAGACT TATCTTCTCGTTGCTTCTTATATAGCTTGAAGGCATTAAATAGATTCACAATCAGCCACAGAGGATAATA ACAGCCTAGAATGTAAAAGCTACTTAGTTATCTAACATGCTACATTCATTCATGAGGCCTTTCCTCTTTG TCTTCCACTGTGCTTTAAGAATGGGTATCTAGGGGCTGGTGAGATGGGACAGGAGTTCAGTTCCTAGCAT TCACAGTGTGATGCTCAGACCCAATTCTAACTCCAACTCCAGGGGTACTGCATACACATGTACAAACCCA CACTTTTTCAGAAATATAAACCAATAATATGGTTGTGGATTAAAAAAAAAAAAAAAAAAA
Restriction Sites RsrII-NotI     
ACCN NM_010197
Insert Size 468 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Reference Data
RefSeq BC037601, AAH37601
RefSeq Size 2440 bp
RefSeq ORF 468 bp
Locus ID 14164
UniProt ID P61148
Gene Summary Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrin ITGAV:ITGB3. Its binding to integrin, subsequent ternary complex formation with integrin and FGFR1, and the recruitment of PTPN11 to the complex are essential for FGF1 signaling. Induces the phosphorylation and activation of FGFR1, FRS2, MAPK3/ERK1, MAPK1/ERK2 and AKT1. Can induce angiogenesis.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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