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Icosl (NM_015790) Mouse Untagged Clone
CAT＃: MC202216
Icosl (untagged) - Mouse icos ligand (Icosl), (10ug)
CNY 2,400.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | AU044799; B7-H2; B7h; B7RP-1; BG071784; GI50; GL50; GL50-B; ICOS-L; Icoslg; LICOS; Ly115l |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC029227 sequence for NM_015790
AGCGGGTCTCCTGCCGCCAAAGCCTCAAGAACCCCAGATTTCAGCGCCCCAAGCCTGGAAGCTCCCCAGT TCTTCGTGGCCCCCAACAGCTCCGGAACCCCAGCCGCTGCAACTCTCCGCGTCCGAAATCCAGCACCCCG CAGTCTGCGCTCGCACCATGCAGCTAAAGTGTCCCTGTTTTGTGTCCTTGGGAACCAGGCAGCCTGTTTG GAAGAAGCTCCATGTTTCTAGCGGGTTCTTTTCTGGTCTTGGTCTGTTCTTGCTGCTGTTGAGCAGCCTC TGTGCTGCCTCTGCAGAGACTGAAGTCGGTGCAATGGTGGGCAGCAATGTGGTGCTCAGCTGCATTGACC CCCACAGACGCCATTTCAACTTGAGTGGTCTGTATGTCTATTGGCAAATCGAAAACCCAGAAGTTTCGGT GACTTACTACCTGCCTTACAAGTCTCCAGGGATCAATGTGGACAGTTCCTACAAGAACAGGGGCCATCTG TCCCTGGACTCCATGAAGCAGGGTAACTTCTCTCTGTACCTGAAGAATGTCACCCCTCAGGATACCCAGG AGTTCACATGCCGGGTATTTATGAATACAGCCACAGAGTTAGTCAAGATCTTGGAAGAGGTGGTCAGGCT GCGTGTGGCAGCAAACTTCAGTACACCTGTCATCAGCACCTCTGATAGCTCCAACCCGGGCCAGGAACGT ACCTACACCTGCATGTCCAAGAATGGCTACCCAGAGCCCAACCTGTATTGGATCAACACAACGGACAATA GCCTAATAGACACGGCTCTGCAGAATAACACTGTCTACTTGAACAAGTTGGGCCTGTATGATGTAATCAG CACATTAAGGCTCCCTTGGACATCTCGTGGGGATGTTCTGTGCTGCGTAGAGAATGTGGCTCTCCACCAG AACATCACTAGCATTAGCCAGGCAGAAAGTTTCACTGGAAATAACACAAAGAACCCACAGGAAACCCACA ATAATGAGTTAAAAGTCCTTGTCCCCGTCCTTGCTGTACTGGCGGCAGCGGCATTCGTTTCCTTCATCAT ATACAGACGCACGCGTCCCCACCGAAGCTATACAGGACCCAAGACTGTACAGCTTGAACTTACAGACCAC GCCTGACAGGACTCTGCCCAGGATATGGACAGGGTTTCTGTGAGTTGCCACCAGGTGGATGTCAGACACA ACTTCAGAGTGGACCCCCACAGGCCTGGTGACAGAGGACAACGAGCTGTCTGCTTATGGGCTGTGATGGA GGCCAGGAATCCCTGGCTTTACGAGGCACAGAGACTTCATCCCAGAAACCCCGAGGGAGATCTCTCCAGT GGGCAGCAGCAACATCATCGGAATATGGAGCCTCCGGTGAGCTGTCGGCACAGAGAGCAGCAGCTTGTGA GAAGATCCTTCCTTGGCACGTTACTACTCAGGCCTAGGAGCTTTATAAAAGAGCGTTTGAGCCACTCTGA AAGCCCTACAGAGTCTACTGGAGACTTTCCCTGCAGGACCTTCAGTTGGGGAGGAAGCCTGACTTTATTT AGGTCTCAGGCTACTTGGGCCTCTTCGAGGATATGTGGGATTTTGTCTACTGCAAACCTGTTTCTGGCTG ACAATGGTTGGGCTCAGAGGCACTCAGCTTCACAACATCAATGGGACACGCCTCATCCTTGACTTCCTGT GGCTACAGAAGCTTTCCGAAAGCCTTGAGCTCTTTCAGACTGAACAGCTCTGCCCAGTCTCAGCAGCCCA TGAAGATCTCAACTCCAGCTTCCTGGGTCTCCGTGTTGCTGGCCAGAATAGAGCTAGCTCTTTTGTTTCA AGATGGTTCTGCAAAGTTGGCTGCTTGGAAACCTAGGGATGTATGTACAAGCTCCAGGCTGATGCAGTAG GGGGCACGGACTCCCCGATGGAACACAGTATCTGACCCTAGGTGAGGGCAAGCTCCTTCCCACGCAGAGG ACTGGAAATTCTGGACCGTCAAGGCCTGTCTGCTATGTGGCTGGGGCTCAGTGCTGATGGATGTGTGAGA TCTCAGGAATGAGGAGTGAGAACCCTGGGCTCAGGACTAGGAAGACCTGTCCATTTTTTTTTTTTTTTAA TGCCCACATGGACTTTTTATTCTTCACACCGATGTATTCAATGAGTGTAGAGAGAACTACTTAAGTCCTT CCCGAGTACAAAGCATTACCTACCTGCAGAATAGCAACTGTTGTTATGGGTCTTGAGTTGGCAGCTACAG CAAACAAGCACAAGGAGCAGTTGGGGTGCAAGAAGATGGGGTGCAGCGCCCCCAAGGACAGACATTTGGG AATTAGTGGTCTCCCTGATGCCCATAGTTCCCCAGGAACTCAGGTGGGTCTGCGGCAGCACAGTAGGAGT ATTCCTCCTACTTTAACTTTTCTTGTCAGACGTAGTTTAGGTTCAGAAAGAGGTCAACTCAGCAAGCCAG CTAGCCGCCTTGGGGCACCAGACACACTGCCCCCCACCCCCTGCTTATGTAGGCATTGGGAACCCTTCAC AGACCACTGGCTGTACAGTCACCATCACCTGCTGATTCCAGCAGGCCCCCACCTTCTTGTGGAATCCTGG GAGCACTCCCCTCTTACCCCTCACTGCCCCCCACCCCCTGCACATCAGCATTCATTAGATTTGCCCTGTA ACGTCTGATTCCTCCTTTATCTGGGTTGTAGATGGGGCATAGTGACTTTTAGAAACCTAACAAGGGAATA AATGTAAGATGTGCTTTCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAA |
| Restriction Sites | RsrII-NotI |
| ACCN | NM_015790 |
| Insert Size | 969 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC029227, AAH29227 |
| RefSeq Size | 2803 bp |
| RefSeq ORF | 969 bp |
| Locus ID | 50723 |
| UniProt ID | Q9JHJ8 |
| Gene Summary | Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function. During pregnancy, may function to skew the cytokine of maternal T-cells toward immunoprotective Th2 phenotype.[UniProtKB/Swiss-Prot Function] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Role of endocytosis and trans-endocytosis in ICOS costimulator-induced downmodulation of the ICOS Ligand
,Aragoneses-Fenoll, L;Montes-Casado, M;Ojeda, G;García-Paredes, L;Arimura, Y;Yagi, J;Dianzani, U;Portolés, P;Rojo, JM;,
Journal of leukocyte biology
,PubMed ID 33527556
[ICOSL]
|
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG204667 | Icosl (tGFP-tagged) - Mouse icos ligand (Icosl) |
CNY 2,850.00 |
|
| MR204667 | Icosl (Myc-DDK-tagged) - Mouse icos ligand (Icosl) |
CNY 2,400.00 |
|
| MR204667L3 | Lenti ORF clone of Icosl (Myc-DDK-tagged) - Mouse icos ligand (Icosl) |
CNY 4,750.00 |
|
| MR204667L4 | Lenti ORF clone of Icosl (mGFP-tagged) - Mouse icos ligand (Icosl) |
CNY 4,800.00 |
