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Wdr4 (NM_021322) Mouse Untagged Clone
CAT＃: MC201825
Wdr4 (untagged) - Mouse WD repeat domain 4 (Wdr4), (10ug)
CNY 3,656.00
| Cited in 1 publication. |
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Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | AI415180; AI448349; D530049K22Rik; Wh |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC039272 sequence for NM_021322
CCCACGCGTCCGCGGAGGCGGCGGGCGGGCCCATGGCGAGCTCTGCGGGGCTGGCACTGTGCGCCCAGAC GCTGGTGGTGCGAGGAGGCAGCCGGTTCCTAGCCTTCTCCACTACGGGCAGTGATGATGACTGTGTCTTC ACATACGACTGCAGTACTGCAGAGAAGAAGGCCACGCCAGAAGATAAAGGGGAGGACGGACAGCCCGCAG ACACAGGGAGTGACTCGATTCTGGCGTCCACCTTCTCCAAGTCTGGCCGCTATTTTGCTTTAACAGATGA CAGTAAGCGTCTGATTCTTTTCCGTACAAAACCATGGCAATGTCTGAGTGTCAGGATGGTGGTGCGGAGG TGCACCGCCCTGACCTTCACAGCCTCAGAGGACCGAGTCTTGGTGGCTGACAAGTCTGGAGACGTCTACT CCTTTTCGGTGCTGGAGCCAGATGGATGTGGCAGGCTGGAGCTTGGGCACCTCTCCATGCTGCTAGACGT GGCTGTGAGTCCTGATGACCAGTTTGTGCTTACTGCAGACCGGGATGAGAAGATCCGGGTCAGCTGGGCT GCTGCCCCGCATAGCATCGAGTCTTTCTGCCTGGGACACACTGAGTTTGTGAGCCGCATCCTTGTAGTGC CCAGTCATCCTGAACTGCTGCTTTCTTCCTCTGGGGATGGCACCCTGAGACTCTGGGAGTACAGAAGCGG TAGGCAGCTGCAGTGCTGTGACCTGGCCGGCCTACAGGAGCCTGGAGAGCAGCCAGGCCACAAGGGGTTG GCCGCGTCCAGGATTGCATTCTGGGGACAGGAGAGCTATGTGGTGCTTCTGTGTGAGTGCGTTCCCGTGG TCTTCGTCTTCCAGCTTGATGCCAGCAGACAGCAGCTGGTGTTCAGACAGCGGCTGACTTTCCCTCACCG AGTGTGGGATGTTGTGTTTGAGGAGGCCCGGGGGCTGTGGGTTCTACAGGACTGCCGTGATGCCCCCCTG GTGCTCTGGAGGCCTGTGGGTGGTGAGTGGCAGGCTGCTCCAGACGGTGCTGTGTCCCCGAGACTCTGCA GCCATCTCCGTGAGAGCTGGGCCATGCTGGAAGGTTCTGTTGGTACAGATGACAGCTTCCGCAGCCTGTA CAAGGCCACCTTTGACAACATGACCTCTTACCTGAAGAAAAAGGAAGAGAGACTGCAGCAGCAGCTGAAG AAGAAGCGGCAAAGGAGCCCCTTCCCAGGGTCCCCGGAACAGACCAAAAAGGCGTGCCCGGGCCAGTCAG CCCTTAGTTGCTGACCTTGGACATGGCCACAGCTCTCATTCCTGAGGCCCTGTGGGCAGCTCTCTCCCTC CTCCTCCCTGGTTCATCCCTAGGGAGGGAGATCACGGCAGCTCAGTCCCTACCACTAGCTCAACAGTCCC TGATCTCCAGAGTCTGCCTTTGTCACTGAGAACAGGCTCCTGCCGGGTTGCAGGGAAGGCAGGTGGTGTT AGCTTAGCTAAGAGTCTAGAGCTGTGTGGAAGCACCTTCACATTGAAGGATACACTGGCCCACAGCACCA CGCATGTCTGTCGGGGCCCACAGTGTCGTCCCTGGGGAGCTCTAGGGAGACCTGCAGGACAGGACCTGCC TTCACATCATTGCCGGGGGCTCTCCAGGTGGAGCTCTGTATGGCTCTGTAGCTGCTTGCTGTTTTGAGGC AGATTCAGTTGGTGCTGTTCGCACTCCTGGGCTGGGCTGAGCAGACTGAGCAAGCTTTGGGGCTCTGAGG GTGTGACCTTGCCAGGCCAGCCTTGTTTTACAGGGAATGATGGTGACCTCGTGGTTCTGTTGCTCTGAAC TCTGCATACACTGCAGAACAGAAGGAAATGAACAGAAATCACAGCATCAATAAAGACAAACTTTGCATAG CTTTCTGGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | RsrII-NotI |
| ACCN | NM_021322 |
| Insert Size | 1242 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC039272, AAH39272 |
| RefSeq Size | 2054 bp |
| RefSeq ORF | 1242 bp |
| Locus ID | 57773 |
| UniProt ID | Q9EP82 |
| Gene Summary | Non-catalytic component of a methyltransferase complex required for the formation of N(7)-methylguanine in a subset of RNA species, such as tRNAs, mRNAs and microRNAs (miRNAs) (PubMed:29983320). In the methyltransferase complex, it is required to stabilize and induce conformational changes of the catalytic subunit (By similarity). Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (PubMed:29983320). Also required for the formation of N(7)-methylguanine at internal sites in a subset of mRNAs (By similarity). Also required for methylation of a specific subset of miRNAs, such as let-7 (By similarity). Acts as a regulator of embryonic stem cell self-renewal and differentiation (PubMed:29983320). Independently of METTL1, also plays a role in genome stability: localizes at the DNA replication site and regulates endonucleolytic activities of FEN1 (PubMed:29574139).[UniProtKB/Swiss-Prot Function] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Wdr4 promotes cerebellar development and locomotion through Arhgap17-mediated Rac1 activation
,null,
Cell Death & Disease
,PubMed ID 36681682
[Wdr4]
|
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Other Versions
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| MG216848 | Wdr4 (tGFP-tagged) - Mouse WD repeat domain 4 (Wdr4), (10ug) |
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| MR216848 | Wdr4 (Myc-DDK-tagged) - Mouse WD repeat domain 4 (Wdr4) |
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| MR216848L3 | Lenti ORF clone of Wdr4 (Myc-DDK-tagged) - Mouse WD repeat domain 4 (Wdr4) |
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| MR216848L4 | Lenti ORF clone of Wdr4 (mGFP-tagged) - Mouse WD repeat domain 4 (Wdr4) |
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