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Brd8 (NM_030147) Mouse Untagged Clone
CAT＃: MC201594
Brd8 (untagged) - Mouse bromodomain containing 8 (Brd8), (10ug)
CNY 10,120.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 2610007E11Rik; 4432404P07Rik; SMAP |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC025644 sequence for NM_030147
CCACGCGTCCGCCCACGCGTCCGCCCACGCGTCCGCCCACGCGTCCGCCAAGATGGCGACCGGGACAGGC AAGCACAAGCTGCTGAGTACTGGCCCAACAGAGCCATGGTCCATCCGAGAGAAGTTGTGTTTAGCATCTT CTGTCATGAGGAGTGGGGATCAGAACTGGGTATCAGTTAGCAGAGCAATCAAGCCCTTTGCAGAACCTGG CCGGCCTCCAGACTGGTTCTCTCAAAAACATTGTGCTTCTCAGTATTCTGAGCTCTTAGAGACTACTGAG ACTCCAAAACGGAAACGGGGTGAAAAAGGAGAAGTGGTAGAAACTGTTGAAGATGTTATTGTTCGCAAAC TGACTGCTGAGAGAGTTGAAGAACTGAAGAAAGTCATAAAGGAGACACAGGAGAGATACAGGCGTCTGAA AAGAGATGCAGAACTAATCCAAGCCGGGCACATGGACAGCAGACTGGATGAGCTCTGCAATGACATTGCA ATGAAAAAGAAATTGGAAGAGGAAGAGGCTGAAGTAAAAAGGAAGGCCACCGATGCTGCGTACCAGGCGC GACAAGCAGTGAAAACGCCTCCTCGAAGGTTACCGACTGTGATGGTCCGCTCTCCTGTAGACTCTGCCTC CCCAGGAGGTGATTACCCACTTGGAGACTTGACTCCAACCACTATGGAAGAGGCTACCTCTGGGGTAACC CCTGGGACTTTGCCGAGTACCCCAGTCACCTCGTTTCCTGGGATTCCTGACACCCTTCCTCCAGGCTCTG CACCCTTAGAAGCCCCCATGACCCCAATAACAGATGATTCACCCCAGAAAAAGATGCTTGGACAGAAAGC AACTCCACCCCCCTCCCCTCTGCTGTCAGAGCTCTTGAAGAAGGGCAGCCTCCTGCCTACTAGCCCCAGA CTGGTGAATGAGAGTGAAATGCCTGTACCCCCTGGCCATCTGAACAGCACAGGGGTTCTCTTGGAGGTAG GAGGGGTTCTTCCCATGATACATGGTGGGGAGATACAGCCAACAACCAGTGCTGTGGCGGCCTCCCCGGC TGCCTCAGGTGCTCCCACTCTTTCCCGGCTTTTAGAAGCTGGGCCCACACAGTTCACCACTCCTCTTCCT TCCTTCACTACTGTTGCCAGTGAGCCGCCAGTTAAGCTTGTGCCACCCCCTGTAGAGTCTGTGTCCCAGG CTACCATTGTCATGATGCCCGCGCTGCCAGCACCATCCTCTGCTGCGGCTGTCTCCACTTCTGAAAGTGG AGCTCCAGTGAGCCAGCCTGAGCCCTGTGTACCCCTGGAAGCTGTGGGGGATCCACATACTGTGACTGTT TCCATGGATAGCAATGAAATCTCCATGATCATTAATTCCATCAAAGAAGAGTGTTTCCGCTCAGGGGTAG CAGAGGCTCCTGGTGGATCAAAGGCTCCAAGCATAGATGGGAAGGAAGACTTGGATCTAGCGGAGAAGAT GGATATTGCTGTGTCTTACACAGGTGAAGAGTTGGACTTTGAAACAGTTGGAGACATCATTGCCATCATT GAGGACAAGGTGGATGATCACCCTGAAGTGCTGGATGTGGCAGCGGTAGAAGCGGCGTTATCGTTCTGTG AAGAGAATGATGACCCTCAGTCCCTGCCTGGCCCCTGGGAGCACCCTATCCAGCAGGAGCGCGACAAGCC AGTACCTCTGCCAGCACCAGAGATGACAGTCAAACAAGAGAGGCTAGACTTCGAGGAATCAGAAAACAAA GGGCTCCATGACCTGGTGGACATCAGGGATTCCGGTGTTGAGATTAAGGTGGAACCCACAGAGCCAGAGC CAGGCATGTCTGGGGCTGAGATAGTAGCTGGAGTTGGTCCAGTTCCAAGTATGGAGCCACCAGAACTCAG GAGTCAAGACTCAGATGAAGAACCTAGAAGTTCTGCAGCTGGAGACATTGGTGAGGCAGATGGTTCCAGT GGGAAAGGCGATGAGAGGCCACTTTCAGCTGTGAAGACAGAGGCATCCCCTGAGAGCATGTTGTCTCCAT CACATGGCTCAAATCTTATTGAAGATCCTTTAGAGGCAGAGACTCAACACAAGTTTGAAATGTCAGACTC ATTGAAAGAAGAATCAGGGACTATTTTTGGAAGCCAGATAAAGGATGCCCCAGGTGACGATGAGGAAGAA GATGGAGTCAGTGAAGCAGCTAGCCTAGAGGAGCCTAAGGAAGAGGATCAAGGAGAAGGCTATTTGTCTG AGATGGATAATGAGCCCCCTGTGAGTGAGAGTGATGATGGCTTTAGTATACATAACGCCACACTGCAGTC ACACACTCTGGCAGACTCCATCCCAAGCAGCCCTGCCTCCTCCCAGTTTTCCGTGTGCAGTGAAGATCAA GAAGCAATTCAGGCTCAGAAAATATGGAAGAAAGCCATCATGCTTGTATGGAGGGCTGCAGCAAATCATA GGTATGCCAATGTGTTCCTGCAACCTGTTACAGATGACATAGCTCCTGGTTACCATAGCATTGTACAGAG GCCTATGGATTTGTCAACTATAAAGAAAAACATTGAAAATGGACTGATCCGAAGCACAGCTGAGTTTCAG CGTGACATCATGCTGATGTTTCAGAATGCTGTTATGTACAATAGCTCAGACCATGATGTCTATCACATGG CAGTAGAGATGCAGAGAGATGTCTTGGAACAGATCCAGCAATTCTTGGCCACACAGTTGATTATGCAAAC ATCTGAGTCTGGAATCAGTGCTAAAAGTCTCCGGGGGAGAGACTCTACCCGAAAACAAGATGCTTCAGAG AAGGACAGTGTCCCCATGGGCTCTCCTGCCTTCCTTCTCTCTCTCTTTGATGGGGGAACCAGGGGACGCC GCTGTGCCATTGAAGCAGATATGAAGATGAAGAAGTGAATGCCCTCTTTGAGCTGAGCCTGAAATAGAAA TAAGCAAGATACTTTAGCTTGGGCTTGTGGGCTCAGTTCCACACTTGATCTTAGTCAAAAGGCTGAGAAG CAGGGAGTCCAGAAGTGGAATTACAGAAGAGGAGGTGCCTGGGCCAAATGACATGAGTTGAGAAAATCTC TTTTCAGAGAGTTGGAGTAGCACAGATGCCTGTTTTAGGGCAGAAATCATGGGCTCTGTTAATGCCCTAA TGTGTAACTAGCAGATTGTAGCTAATTTGTACTGTCTTGTGAAGTGTACAGATTTTTTAAATAATAATAA TAATAAACCTGTGAAGTGTGTATATATAACAATCAGAAGGAAAAAAAAAAAAAAAAA |
| Restriction Sites | RsrII-NotI |
| ACCN | NM_030147 |
| Insert Size | 2763 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | BC025644, AAH25644 |
| RefSeq Size | 3277 bp |
| RefSeq ORF | 2763 bp |
| Locus ID | 78656 |
| UniProt ID | Q8R3B7 |
| Gene Summary | May act as a coactivator during transcriptional activation by hormone-activated nuclear receptors (NR). Stimulates transcriptional activation by AR/DHTR, ESR1/NR3A1, RXRA/NR2B1 and THRB/ERBA2. Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AFZ from the nucleosome.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longest transcript. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG223690 | Brd8 (tGFP-tagged) - Mouse bromodomain containing 8 (Brd8), (10ug) |
CNY 10,450.00 |
|
| MR223690 | Brd8 (Myc-DDK-tagged) - Mouse bromodomain containing 8 (Brd8) |
CNY 10,448.00 |
|
| MR223690L3 | Lenti ORF clone of Brd8 (Myc-DDK-tagged) - Mouse bromodomain containing 8 (Brd8) |
CNY 11,400.00 |
|
| MR223690L4 | Lenti ORF clone of Brd8 (mGFP-tagged) - Mouse bromodomain containing 8 (Brd8) |
CNY 11,400.00 |
