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Cmtm6 (NM_026036) Mouse Untagged Clone
CAT＃: MC201503
Cmtm6 (untagged) - Mouse CKLF-like MARVEL transmembrane domain containing 6 (Cmtm6), (10ug)
CNY 2,400.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 2810051A14Rik; AA536733; Cklfsf6 |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC027248 sequence for NM_026036
GGGCGATGGAGAACGGAGCGGTCTACAGTCCCACCACCGAGGCGGCCCCGGGCACTGGCAGGGGTGCGCG CAGCGGCCTGGCCGCCTACTTCGTCCTGGGCAGGCTCCCTTGGCATCGGCGCATCCTCAAAGGCTTGCAG CTGCTGCTGTCTCTCCTGGCCTTCATCTGTGAAGAGGTTGTGTCCGAGTGTGGGTTGTGTGGAGGCCTCT ACTTCTTTGAATTTGTGAGCTGTAGCGCCTTTCTCCTGAGCCTCCTCCTGCTGATCGTGTACTGCACCCC AGTGCACGACAGAGTGGATACTGGAAAAGTCAAGTCATCGGATTTTTACATCACCCTGGGAACTGGGTGT GTGTTCCTGCTGGCATCTATCATTTTTGTCTCCACCCATTCTGGGACCTCAGCTGAAATTGCTGCAATTG TGTTTGGCTTCTTGGCAAGCTCCATGTTCCTACTGGACTTCGTTGTCATGCTGTGTGAGAAGCTGCGGGA GAGCCCGCTGAGAAAGCCCGAGAACAACGCAAAGGTGGAAGCCCTCACCGAACCACTGAACGCTTAAAGA CACAGAGCCGGGGTGTGGACCCAAAGAGAGGCTCCCTCTGTGTGACCTGTGTCGTGTGTGCACCTTTTGG AGAGAAGGGAAGGGACAGGAGAGCAGCTTTACAGCGCTGGGCTGGGTGGCAGTGCTGGGCTGGGTGGCAG CCCCAGCAGGAAGCTCAGAGGGTTTGTAATAATGCTTGGAACCTGTCGCGAGTGGAGGAGGATTGTTTGT TTTGTTTTGTTTTGTTTGTTTGTTTTGTTTTGTTTTTAGAGATGAGGACTGCTGTCCTTTGAATTGCATG TCTGTCATTTTGCTATAGGACGCCCCTCACCACGCTTACCTTCCAGACTGTGCCTTTTCCGTCCTTTCAG GAACCGGTTAACTTCTGTTGTTGCCGGAGATTTAATGAGTGTTTAAGATGCTGGTGTAGGCGTCTTTCCT TAATGTTATGATCCTTTACTGTATCTTACTCAGCCTTACACTTAATGTGCTAACCTCTTAAAGCAATTAT TCTTAATTCCTTCTGAGCCATGCATTGCCTAACAGAAAGCGTGTGGGCTGGTGCTGTTTATGTGTGTGAA AGCAACCGTGTAGCAGCCTTGTGGAGGCTTTTACATTGCACTGTGATTGCTGAGATTAAGTTTAGAAGAA AATGAAGTTATGTAACACTGGAAAGTGAGGGAGCTGATAGTCTATCTAAAGACCAAAGAGAGAAGAGACT GTCCCGCACCGCGGGTGTAATCACATGGCTAGGCCTTTGCAACTCGGCAGAGATGTGAGGGTCGGTGCTG TGTTCACCCGTGCAAACAGGGTTGATGGCGTCAAACTAGAGACTTGTGGGTCTCCCTCCGGGCAGATGGT TTCTGCTCAAGCGAGCACAGCTCCGCAGGCTTCTCTGCAGAGCCTAGGCTGGGATCTCTGGCCCGCCAGA TTCTCCTTCCTGACTTTCTCTAGAATGGTCCCGTGCCCTGCCGTGTGCCGTCTGTGAAGGCCAGTGCTCG CTCTTCCTCTCTGTTCTCTTCCCATTGTCAGCCGTCTCCAGGCCATCCAGAGGTGTGTCCCTTCTCACCA GGAGTCTGAGGCAGAGGTGTCAGGTCCGTGTTCCCTCCCACAGGCCTCTGCTTGGGTTTCTTTCTCTCCA GGGGAGAGGTCTTGAAGATGTAAACCCCTGAAGCCCTGCTAGTGAGTACTGCTGGTGGTGTGGGGAGGCC GCAGGCCTCCTGGGACTCTGGAAGGATCGCTTGCTGCTGGAGGGCTGTCTTAGAACCACTGGGCGCCCTT CCGACCCGGGGGACCCTTCTTCCCTTCTTGCCTTCTTCCTAGAGCTTGAGCGAGATCCAGCACGTCCAGG CCTTCTGTGCACTGGCCAAGGTTTCCCAGGCTGGGCTTTCTCTTTGGAGTGGTGCGATGGATCGTGTTTC CGGGGATTCACTGTAAAGTCCCCGTCCTTTCCAGTGTCTTGCGTGCCTGGTGTGTGGAAGGAGATGGTTT CAGTTTCCTAGTGAGGCTGTGGCAGTTCTTGGAAGTGGATGAATCTGGGCACACAGCTTCTGCCCTGTCC CTGCCTCACTGCCTGATCTGCTGTCCTCAAGGTTTACATACTGGTGATGTCACCATAGCTGCTCTGGAGA TCATGAAACTGATCCTTAACATTGCCTTACTGGACATGCCATTCCAGAGAGGGGACAGTAGGCTCTTGAA ACCAAGAATAGAGAAGTTCAAAAGTAACCAGTCTATTGCAGACAATTTTAGAGTTTTATATCAAGCTGTG CTGTAAATATCATTTAGACCTATTGAGAATTAACAGCAAATCTGAGCTACTTTAGTGTTACCAACTATTA GTCTGCTGACTGTTTCTATAACAAAATACCTGAGACAATCAACTTAAAAAGAGGAAGGGTTGGGGAAAAG GTTAATCTTGGCTTGCAGTTTTGTAGGCTTTGGCCCTTAGTCAGACCTGCTGTTTTAGACAGCAACACAT CACTTGGGGAGTTTGTTGTAGATCTGGAAGCAAGGAAAGAAGGGCGGTGGCTTGAGGTCCTGAGGTCACT TAAGGGCACACCCTCTCTGACCTAAGACCTCACTAGGCCCCGCCTCTAAAGGTTTCTGACCTCAATAGTG CCTTCCTGGAGAACTAGTTTCTAACTCTCAGGCCCTTGGGGACATTGCATCTCAGTAGTAGGTGCCTCTC TACCTGTGTTTGGCTTGTTCATGATTGGCAGACACTCTGCCTGGCTCTGCACAGCAGCGGCTCAGCATCA GCATCCAGCTGCTTGCTGTGTGTTAGTTGTCTCACAGCTGAGGGCTCTGCCTCGGCTACTTCAGGCTTTC CGGTTAGGAAGATAATTTGGTCACTTGTGTCTGTGGCCACTCTTAGAATTTTCTCTTTTGAGGGAACCTG TGACTGGTTGGCTTTTGCATTCTATGGAGGGAGATGGGGTTAAAGACTGTGGCAACACACACCCTCCAGA AGAGCTGGGACCAGAGACTGTCAGCACAGAAAGGACAATGTCTTTTTTAGTAGCTGTGGCAGACTTGAGT TGCTGTAATTTATACAAATTGTTTAGAATGGTTTTTAAGACTAAGAAGGGAAATATACTTATTGCACAAG ACTTTTATAATTACTATACTTAAATTATGCTCTATGTGGGGACTGAGAAGTGTATTTCTACGTTGCTTAT ATCTGATCACTTTTGTATTTGTTGATTTAAAGCCTGTGGGTCTTTTTTTTTAATCACTCTTAATATCAAC TTTTATAATCTTTTAAAATAAATCCTCTTAATTCCAAAAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | RsrII-NotI |
| ACCN | NM_026036 |
| Insert Size | 552 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC027248, AAH27248 |
| RefSeq Size | 3347 bp |
| RefSeq ORF | 552 bp |
| Locus ID | 67213 |
| UniProt ID | Q9CZ69 |
| Gene Summary | Master regulator of recycling and plasma membrane expression of PD-L1/CD274, an immune inhibitory ligand critical for immune tolerance to self and antitumor immunity. Associates with both constitutive and IFNG-induced PD-L1/CD274 at recycling endosomes, where it protects PD-L1/CD274 from being targeted for lysosomal degradation, likely by preventing its ubiquitination. May stabilize PD-L1/CD274 expression on antigen presenting cells and potentiates inhibitory signaling by PDCD1/CD279, its receptor on T-cells, ultimately triggering T-cell anergy.[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG201673 | Cmtm6 (tGFP-tagged) - Mouse CKLF-like MARVEL transmembrane domain containing 6 (Cmtm6) |
CNY 2,850.00 |
|
| MR201673 | Cmtm6 (Myc-DDK-tagged) - Mouse CKLF-like MARVEL transmembrane domain containing 6 (Cmtm6) |
CNY 2,400.00 |
|
| MR201673L3 | Lenti ORF clone of Cmtm6 (Myc-DDK-tagged) - Mouse CKLF-like MARVEL transmembrane domain containing 6 (Cmtm6) |
CNY 4,750.00 |
|
| MR201673L4 | Lenti ORF clone of Cmtm6 (mGFP-tagged) - Mouse CKLF-like MARVEL transmembrane domain containing 6 (Cmtm6) |
CNY 4,750.00 |
